We investigated the relation between self-reported hearing loss and risk of subjective cognitive function (SCF) decline among women. Read & Research Alzheimer’s More

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Prospective studies reporting associations between cognitive performance and subsequent incident dementia have been subject to attrition bias. Furthermore, the extent to which established risk factors account for such associations requires further elucidation. Read & Research Alzheimer’s More

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A new study attributes the link between tau protein clumping and brain damage in Alzheimer’s disease to brain immune cells called microglia. Read & Research Alzheimer’s More

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Acetylcholine is a neurotransmitter that plays a key role in brain and muscle function. Here, we look at what acetylcholine does and describe medical conditions linked with it, including Alzheimer’s and Parkinson’s, and their treatments. Read & Research Alzheimer’s More

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To determine if sleep-disordered breathing (SDB), daytime sleepiness, insomnia, and sleep duration predict seven-year neurocognitive decline in US Hispanics/Latinos (N = 5247). Read & Research Alzheimer’s More

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Although the relationship between APOE and Alzheimer’s disease (AD) is well established in populations of European descent, the effects of APOE and ancestry on AD risk in diverse populations is not well understood. Read & Research Alzheimer’s More

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New research in mice suggests that dabigatran, a blood thinning drug, may help delay the development of Alzheimer’s by maintaining normal brain blood flow. Read & Research Alzheimer’s More

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We examined the influence of enrollment factors demonstrated to differ by race on incident mild cognitive impairment and dementia using Alzheimer’s Disease Center data. Read & Research Alzheimer’s More

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Alzheimer’s disease (AD) is a disabling, common cause of dementia, and agitation is one of the most common and distressing symptoms for patients with AD. Escitalopram for agitation in Alzheimer’s disease (S-CitAD) tests a novel, clinically derived therapeutic approach to treat agitation in patients with AD. Read & Research Alzheimer’s More

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The objective of this study was to assess the usefulness of the appropriate use criteria (AUC) for amyloid imaging in an unselected cohort. Read & Research Alzheimer’s More

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The aim of this study was to investigate the registry-based national time trends in incidence and prevalence rates of dementia from 1996 to 2015. Read & Research Alzheimer’s More

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The associations between self-reported current and past leisure time physical activity (LTPA) and Alzheimer’s disease (AD) incidence were determined using data from the multiethnic Washington/Hamilton Heights-Inwood Columbia Aging Project (WHICAP) study. Read & Research Alzheimer’s More

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A large scale global study from ADI and the London School of Economics and Political Science examines the attitudes of people toward dementia. Read & Research Alzheimer’s More

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The relationship between alcohol consumption and dementia risk in older adults is proving difficult to unpick. A recent study takes a fresh look. Read & Research Alzheimer’s More

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The 2018 National Institute on Aging and the Alzheimer’s Association (NIA-AA) research framework recently redefined Alzheimer’s disease (AD) as a biological construct, based on in vivo biomarkers reflecting key neuropathologic features. Combinations of normal/abnormal levels of three biomarker categories, based on single thresholds, form the AD signature profile that defines the Read & Research Alzheimer’s More

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Neuron damage and death in Alzheimer’s and other neurodegenerative diseases may be preventable by targeting a shared cause of inflammation. Read & Research Alzheimer’s More

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New evidence suggests that managing blood pressure may help slow down the progression of cognitive decline in people with Alzheimer’s disease. Read & Research Alzheimer’s More

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The prevalence, mortality, and healthcare impact of Alaska Native and American Indian (ANAI) people with Alzheimer’s disease and related dementias (ADRD) are unknown. Read & Research Alzheimer’s More

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A new study suggests that people with Lewy body dementia and Alzheimer’s have distinct walking patterns that may match cognitive and disease changes. Read & Research Alzheimer’s More

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Questions remain about whether apolipoprotein E (APOE)-ε4 effects on cognitive decline are similar in men and women and how APOE-ε4 and age interact to influence decline in different cognitive domains. Read & Research Alzheimer’s More

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The Multidomain Alzheimer Preventive Trial (MAPT) assessed the efficacy of omega-3 fatty acid supplementation, a multidomain intervention (MI), or a combination of both on cognition. Impact according to cerebral amyloid status was evaluated by PET scan. Read & Research Alzheimer’s More

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A clinical trial has found that an innovative electromagnetic therapy device significantly reduced memory loss in seven out of the eight participants. Read & Research Alzheimer’s More

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We aimed to refine the hypothesis that dementia has a unique signature of gait impairment reflective of underlying pathology by considering two dementia subtypes, Alzheimer’s disease (AD) and Lewy body disease (LBD), and exploring the role of cognition in disease-specific gait impairments. Read & Research Alzheimer’s More

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A new proof-of-concept study finds that people with Alzheimer’s biomarkers in the brain who exercise frequently experience slower deterioration. Read & Research Alzheimer’s More

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Caring for someone with Alzheimer’s disease can be both challenging and rewarding. Learn about tips to make it easier, as well as when to seek professional help. Read & Research Alzheimer’s More

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A recent study concludes that wearing hearing aids is associated with later onset of dementia and a reduced risk of anxiety, depression, and falls. Read & Research Alzheimer’s More

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New research finds a ‘significant’ association between a history of migraine and various forms of dementia, and Alzheimer’s disease in particular. Read & Research Alzheimer’s More

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Environmental factors are poorly understood in the etiology of Alzheimer’s disease (AD) and related dementias. The importance of environmental factors in gene environment interactions (GxE) is suggested by wide individual differences in cognitive loss, even for carriers of AD-risk genetic variants. Read & Research Alzheimer’s More

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Poor gait has recently emerged as a potential prodromal feature of cognitive decline and dementia. We assessed to what extent various aspects of poor gait are independently associated with cognitive decline and incident dementia. Read & Research Alzheimer’s More

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Individuals with homozygosity for the apolipoprotein E (APOE) ε4 allele are in the highest risk category for late-onset Alzheimer’s disease (LOAD). However, some individuals in this category do not develop LOAD beyond the age of 75 years, despite being at elevated genetic risk. These “resilient” individuals may carry protective genetic factors. Read & Research Alzheimer’s More

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