A clinical trial has found that an innovative electromagnetic therapy device significantly reduced memory loss in seven out of the eight participants. Read & Research Alzheimer’s More

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We aimed to refine the hypothesis that dementia has a unique signature of gait impairment reflective of underlying pathology by considering two dementia subtypes, Alzheimer’s disease (AD) and Lewy body disease (LBD), and exploring the role of cognition in disease-specific gait impairments. Read & Research Alzheimer’s More

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A new proof-of-concept study finds that people with Alzheimer’s biomarkers in the brain who exercise frequently experience slower deterioration. Read & Research Alzheimer’s More

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Caring for someone with Alzheimer’s disease can be both challenging and rewarding. Learn about tips to make it easier, as well as when to seek professional help. Read & Research Alzheimer’s More

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A recent study concludes that wearing hearing aids is associated with later onset of dementia and a reduced risk of anxiety, depression, and falls. Read & Research Alzheimer’s More

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New research finds a ‘significant’ association between a history of migraine and various forms of dementia, and Alzheimer’s disease in particular. Read & Research Alzheimer’s More

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Environmental factors are poorly understood in the etiology of Alzheimer’s disease (AD) and related dementias. The importance of environmental factors in gene environment interactions (GxE) is suggested by wide individual differences in cognitive loss, even for carriers of AD-risk genetic variants. Read & Research Alzheimer’s More

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Poor gait has recently emerged as a potential prodromal feature of cognitive decline and dementia. We assessed to what extent various aspects of poor gait are independently associated with cognitive decline and incident dementia. Read & Research Alzheimer’s More

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Individuals with homozygosity for the apolipoprotein E (APOE) ε4 allele are in the highest risk category for late-onset Alzheimer’s disease (LOAD). However, some individuals in this category do not develop LOAD beyond the age of 75 years, despite being at elevated genetic risk. These “resilient” individuals may carry protective genetic factors. Read & Research Alzheimer’s More

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Large longitudinal biomarkers database focusing on middle age is needed for Alzheimer’s disease (AD) prevention. Read & Research Alzheimer’s More

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Raspberry ketones are the compounds that give raspberries their smell. Some people believe that they provide health benefits. Learn about the possible uses and side effects of raspberry ketones here. Read & Research Alzheimer’s More

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It is unclear the degree to which tau pathology in the medial temporal lobe (MTL) measured by 18F-flortaucipir positron emission tomography relates to MTL subregional atrophy and whether this relationship differs between amyloid-β–positive and amyloid-β–negative individuals. Read & Research Alzheimer’s More

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The low mild cognitive impairment (MCI) to cognitively normal (CN) reversion rate in the Alzheimer’s Disease Neuroimaging Initiative (2-3%) suggests the need to examine reversion by other means. We applied comprehensive neuropsychological criteria (NP criteria) to determine the resulting MCI to CN reversion rate. Read & Research Alzheimer’s More

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Plasma proteins have been widely studied as candidate biomarkers to predict brain amyloid deposition to increase recruitment efficiency in secondary prevention clinical trials for Alzheimer’s disease. Most such biomarker studies are targeted to specific proteins or are biased toward high abundant proteins. Read & Research Alzheimer’s More

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There is insufficient understanding of diagnosis of etiologic dementia subtypes and contact with specialized dementia care among older Americans. Read & Research Alzheimer’s More

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Fish oil supplements contain healthful omega-3 fatty acids. These dietary fats are available in fresh fish, as well, but too many may lead to unwanted or even dangerous side effects. Read & Research Alzheimer’s More

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Behavior/Comportment/Personality (BEHAV) and Language (LANG) domains were added to the Clinical Dementia Rating (CDR®) for improving evaluation of patients with frontotemporal lobar degeneration (FTLD) (CDR® plus NACC FTLD). Read & Research Alzheimer’s More

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Large variability among Alzheimer’s disease (AD) cases might impact genetic discoveries and complicate dissection of underlying biological pathways. Read & Research Alzheimer’s More

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Eye tracking tests help to distinguish between two subtypes of mild cognitive impairment and their respective risks of becoming Alzheimer’s. Read & Research Alzheimer’s More

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New research suggests that mindfulness meditation can help boost brain health and improve cognitive reserve in older adults with mild cognitive impairment. Read & Research Alzheimer’s More

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We thank Dr. Mahla for his interest in our work and for highlighting some of the important details of our analysis. While the high risk of developing Alzheimer’s disease (AD) in those with Down syndrome (DS) is well known [1], resulting in DS being the most common genetic cause of Read & Research Alzheimer’s More

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Researchers have found variants of a gene that influence Alzheimer’s disease risk through their effect on a cerebrospinal fluid protein. Read & Research Alzheimer’s More

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A new study asks whether subtle changes to the chemistry of proteins might explain why they build up in the brains of people with Alzheimer’s. Read & Research Alzheimer’s More

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New research suggests that experiencing a stressful life event may detrimentally impact older women’s memories and put them at risk of Alzheimer’s disease. Read & Research Alzheimer’s More

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A new study investigates the importance of fluctuations in blood pressure from mid-age to later life. It asks how these changes relate to dementia risk. Read & Research Alzheimer’s More

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According to a new study, the buildup of toxic tau protein in key areas of the brain leads to major brain cell loss and daytime sleepiness in Alzheimer’s. Read & Research Alzheimer’s More

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Gut microbiota changes before the onset of Alzheimer’s disease (AD) and the alterations could be detected in the stage of mild cognitive impairment (MCI). The findings might offer diagnostic biomarkers before the onset of dementia. Read & Research Alzheimer’s More

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One of the most reliable studies of its kind has tracked participants over a 28-year period and found that greater social activity can lower dementia risk. Read & Research Alzheimer’s More

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Brain function and memory naturally decline slightly as a person ages, but there are many techniques people can use to improve memory and prevent its loss. Learn about them here. Read & Research Alzheimer’s More

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We classified individuals based on their baseline performance on cognitive measures and investigated the association between cognitive classifications and neuropathological findings ∼7 years later, as an external validator. Read & Research Alzheimer’s More

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