Beyond amyloid: Getting real about nonamyloid targets in Alzheimer's disease

By Karl Herrup, Maria C. Carrillo, Dale Schenk, Angela Cacace, Susan DeSanti, Robert Fremeau, Ratan Bhat, Marcie Glicksman, Patrick May, Russell Swerdlow, Linda J. Van Eldik, Lisa J. Bain, Samantha Budd Abstract: For decades, researchers have focused primarily on a pathway initiated by amyloid beta aggregation, amyloid deposition, and accumulation in the brain as the key mechanism underlying the disease and the most important treatment target. However, evidence increasingly suggests that amyloid is deposited early during the course of disease, even Read & Research Alzheimer’s More

Leave a Reply