Long-term anticholinergic use and the aging brain

By Xueya Cai, Noll Campbell, Babar Khan, Christopher Callahan, Malaz Boustani Abstract: Background: Older Americans are facing an epidemic of chronic diseases and are thus exposed to anticholinergics (ACs) that might negatively affect their risk of developing mild cognitive impairment (MCI) or dementia.Objective: To investigate the association between impairment in cognitive function and previous AC exposure.Design: A retrospective cohort study.Setting: Primary Read & Research Alzheimer’s More

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