The influence of insulin infusion on the metabolism of amyloid β peptides in plasma

By Monika Karczewska-Kupczewska, Natalia Lelental, Agnieszka Adamska, Agnieszka Nikołajuk, Irina Kowalska, Maria Górska, Rüdiger Zimmermann, Johannes Kornhuber, Marek Strączkowski, Piotr Lewczuk Abstract: Background: Accumulating body of evidence suggests pathophysiologic links between Alzheimer’s disease and diabetes mellitus (DM). For example, the two crucial peptides playing a role in both degenerative disorders, amyloid β (Aβ) and insulin, are metabolized by the same enzyme, insulin degrading enzyme. Euglycemic hyperinsulinemic clamp is a method of Read & Research Alzheimer’s More

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