Archive for June, 2013

Robo-Pets Help Dementia Patients"> Robo-Pets Help Dementia Patients

Posted June 27, 2013 By FuckAlzheimers

A new study has revealed that therapeutic robot companions can provide a better quality of life for people living with dementia. The researchers found that “PARO”, a large, fluffy robotic harp seal, helped mid-to late-stage sufferers of dementia become less anxious, aggressive and lonely… Read & Research Alzheimer’s More

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Researchers in Berlin and Munich, Germany and Oxford, United Kingdom, have revealed that a protein well known for its role in Alzheimer’s disease controls spindle development in muscle and leads to impaired movement in mice when the protein is absent or treated with inhibitors… Read & Research Alzheimer’s More

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When working a cold case, smart investigators try something new. By taking a novel approach to nuclear magnetic resonance spectroscopy – a blending of four techniques – scientists have been able to resolve a key interaction between two proteins that could never be observed before. They report on their findings Read & Research Alzheimer’s More

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The motor neuron disease Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s Disease, progresses in a stepwise, sequential pattern which can be classified into four distinct stages, report pathologists with the Perelman School of Medicine at the University of Pennsylvania in the Annals of Neurology… Read & Research Alzheimer’s More

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Posted June 21, 2013 By FuckAlzheimers

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Posted June 21, 2013 By FuckAlzheimers

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Posted June 21, 2013 By FuckAlzheimers

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GPS tracking devices, technology that allows real time tracking, are being encouraged by experts to lower the costs of finding dementia patients who have gotten lost. Scientists debate whether they can actually reduce the risk of harm or whether they are simply quick fixes to suit caretakers in new reports Read & Research Alzheimer’s More

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Treating patients with dementia can be viewed as a difficult task for doctors, but Penn State College of Medicine researchers say that storytelling may be one way to improve medical students’ perceptions of people affected by the condition. Participation in a creative storytelling program called TimeSlips creates a substantial improvement Read & Research Alzheimer’s More

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Research shows interaction of tau and amyloid-beta in the brain may cause cognitive decline For years, Alzheimer’s researchers have focused on two proteins that accumulate in the brains of people with Alzheimer’s and may contribute to the disease: plaques made up of the protein amyloid-beta, and tangles of another protein, Read & Research Alzheimer’s More

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Many proteins work like Swiss Army knives, fitting multiple functions into their elaborately folded structures. A bit mysteriously, some proteins manage to multitask even with structures that are unfolded and floppy – “intrinsically disordered… Read & Research Alzheimer’s More

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The first experimental drug to boost brain synapses lost in Alzheimer’s disease has been developed by researchers at Sanford-Burnham Medical Research Institute. The drug, called NitroMemantine, combines two FDA-approved medicines to stop the destructive cascade of changes in the brain that destroys the connections between neurons, leading to memory loss Read & Research Alzheimer’s More

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A new study shows that memory pathology in older mice with Alzheimer’s disease can be reversed with treatment… Read & Research Alzheimer’s More

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Although a family history of Alzheimer’s disease is a primary risk factor for the devastating neurological disorder, mutations in only three genes – the amyloid precursor protein and presenilins 1 and 2 – have been established as causative for inherited, early-onset Alzheimer’s, accounting for about half of such cases… Read & Research Alzheimer’s More

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The layout of white matter brain abnormalities in people after traumatic brain injuries (mTBI) are similar to those found in early Alzheimer’s, according to new research… Read & Research Alzheimer’s More

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A structure called “the microtubule network” is a crucial part of our nervous system. It acts as a transportation system within nerve cells, carrying essential proteins and enabling cell-to-cell communications. But in neurodegenerative diseases like Alzheimer’s, ALS, and Parkinson’s, this network breaks down, hindering motor abilities and cognitive function. Now Read & Research Alzheimer’s More

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In current health lore, antioxidants are all the rage, as “everybody knows” that reducing the amount of “reactive oxygen species” — cell-damaging molecules that are byproducts of cellular metabolism — is critical to staying healthy… Read & Research Alzheimer’s More

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Eli Lilly’s Phase II study for an investigational drug for Alzheimer’s disease has been terminated due to abnormal liver biochemical tests. The company says that clinical study investigators have been informed. The compound in question, a beta secretase (BACE) inhibitor called LY2886721, was being tested as a once-daily therapy to Read & Research Alzheimer’s More

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The propensity of proteins to stick together in large clumps – termed “protein aggregation” – is the culprit behind a variety of conditions including Huntington’s, Alzheimer’s, and mad cow diseases. With this notoriety, protein aggregation is considered to be a bad accident of nature that happens when protein structure is Read & Research Alzheimer’s More

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Multiple drug classes commonly prescribed for common medical conditions are capable of influencing the onset and progression of Alzheimer’s disease, according to researchers at The Mount Sinai Medical Center. The findings are published online in the journal PLoS One… Read & Research Alzheimer’s More

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Sleep researchers from University of California campuses in Riverside and San Diego have identified the sleep mechanism that enables the brain to consolidate emotional memory and found that a popular prescription sleep aid heightens the recollection of and response to negative memories… Read & Research Alzheimer’s More

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A study of older adults with diabetes mellitus (DM) suggests a bidirectional association between hypoglycemic (low blood glucose) events and dementia, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication… Read & Research Alzheimer’s More

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One of the biggest hurdles of hybrid positron emission tomography and magnetic resonance (PET/MR) imaging is the prevalence of motion artifacts – blurring and ghostly visual anomalies caused by patient motion on the table during imaging… Read & Research Alzheimer’s More

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Alzheimer’s disease has been linked in many studies to amyloid plaque buildup in the brain, but new research is finding a common thread between amyloid burden and lower energy levels, or metabolism, of neurons in certain areas of the brain associated with Alzheimer’s disease – even for people with no Read & Research Alzheimer’s More

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The accumulation of amyloid-β (Aβ) in the brains of Alzheimer’s disease (AD) patients is known to be associated with memory loss and neuronal degeneration, but the mechanism of Aβ pathogenesis is not fully understood… Read & Research Alzheimer’s More

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Robots could help apathetic dementia sufferers to shake off some of their apathy. A Spanish research team arrived at this conclusion in a pilot study reported on at the 23rd Meeting of the European Neurological Society (ENS) in Barcelona, where 3,000 experts are gathering to discuss current developments in their Read & Research Alzheimer’s More

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“More than a third of Parkinson’s patients suffer from dementia,” Prof Dr Heinz Reichmann told more than 3,000 experts gathered at the 23rd Meeting of the European Neurological Society (ENS) in Barcelona to discuss the latest developments in the field… Read & Research Alzheimer’s More

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“Progress is currently being made in dementia research particularly in diagnosis. Dementia diagnosis rely mainly on clinical information, and few decades ago, definite diagnosis could not come until an autopsy was conducted. With the advances in the genetic field, definite diagnosis is now possible much before death… Read & Research Alzheimer’s More

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Scientists at the Gladstone Institutes have deciphered how a protein called Arc regulates the activity of neurons – providing much-needed clues into the brain’s ability to form long-lasting memories. These findings, reported in Nature Neuroscience, also offer newfound understanding as to what goes on at the molecular level when this Read & Research Alzheimer’s More

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