Archive for October, 2013

Plaques and tangles made of proteins are believed to contribute to the debilitating progression of Alzheimer’s disease. But proteins also play a positive role in important brain functions, like cell-to-cell communication and immunological response… Read & Research Alzheimer’s More

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Scientists have known for some time that a protein called presenilin plays a role in Alzheimer’s disease, and a new study reveals one intriguing way this happens. It has to do with how materials travel up and down brain cells, which are also called neurons… Read & Research Alzheimer’s More

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The U.S. Food and Drug Administration has approved Vizamyl (flutemetamol F 18 injection), a radioactive diagnostic drug for use with positron emission tomography (PET) imaging of the brain in adults being evaluated for Alzheimer’s disease (AD) and dementia. Dementia is associated with diminishing brain functions such as memory, judgment, language Read & Research Alzheimer’s More

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In what promises to be a major breakthrough in our understanding of Alzheimer’s disease, an international group of scientists has discovered 11 previously unknown genes that increase people’s risk of developing this most common cause of dementia… Read & Research Alzheimer’s More

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“Plant sterols are present in various combinations in nuts, seeds and plant oils. As plant sterols are the equivalents of animal cholesterol, they can in principal influence metabolic processes, where cholesterol is involved,” explained Marcus Grimm, Head of the Experimental Neurology Laboratory at Saarland University… Read & Research Alzheimer’s More

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When on a strict diet, it can be very hard to resist a bar of chocolate if it is right under your nose. Are you likely to eat it there and then? Or wait until the end of the week to intensify the satisfying experience? Whatever your answer, researchers now Read & Research Alzheimer’s More

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If Alzheimer’s disease is to be treated in the future it requires an early diagnosis, which is not yet possible. Now researchers at higher education institutions such as Linkoping University have identified six proteins in spinal fluid that can be used as markers for the illness. Alzheimer’s causes great suffering Read & Research Alzheimer’s More

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Diabetes and dementia are rising dramatically in the United States and worldwide. In the last few years, epidemiological data has accrued showing that older people with diabetes are significantly more likely to develop cognitive deterioration and increased susceptibility to onset of dementia related to Alzheimer’s disease… Read & Research Alzheimer’s More

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Scientists have discovered biological mechanisms that may link Parkinson’s disease to Alzheimer’s disease, according to a study published in the journal Acta Neuropathologica. Researchers from the University of Florida say their findings could lead to targets for new treatment that combats both Alzheimer’s and Parkinson’s disease, as well as many Read & Research Alzheimer’s More

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Anavex Life Sciences Corp. (“Anavex” or the “Company”) (OTCQB: AVXL) has announced that the current issue of the peer-reviewed scientific journal PLOS ONE explains that sigma-1 receptor (Sig-1R) activity is involved in cellular survival by regulating and stabilizing a key cell stress sensor… Read & Research Alzheimer’s More

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New research suggests that people with high blood sugar levels, even those who do not have diabetes, may have an increased risk for developing cognitive impairment. This is according to a study published in the journal Neurology… Read & Research Alzheimer’s More

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Inflammation is the common denominator of many chronic age-related diseases such as arthritis, gout, Alzheimer’s, and diabetes. But according to a Yale School of Medicine study, even in the absence of a disease, inflammation can lead to serious loss of function throughout the body, reducing healthspan – that portion of Read & Research Alzheimer’s More

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New research from the Buck Institute in California offers insights into new treatments targeting the interaction between ApoE4 and SirT1 proteins, moving closer to developing preventative treatments for Alzheimer’s among people genetically predisposed to the disease… Read & Research Alzheimer’s More

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A new study suggests that reduced sleep and poor sleep quality may be linked to increased build-up of beta-amyloid plaques in the brains of older adults – a sign of Alzheimer’s disease. This is according to a study published in the journal JAMA Neurology… Read & Research Alzheimer’s More

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A commonly prescribed statin has been found to reduce inflammation in the brains of mice following surgery – a process that can lead to post-operative cognitive dysfuntion and Alzheimer’s disease. This is according to a study published in the journal Annals of Surgery. Researchers from Imperial College London in the Read & Research Alzheimer’s More

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UC Irvine’s trailblazing 90+ Study, launched in 2003 to learn more about the “oldest old,” the fastest-growing age group in the U.S., will continue for at least another five years, thanks to a $9.5 million renewal grant from the National Institute on Aging… Read & Research Alzheimer’s More

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According to a new study, high long-chain omega-3 polyunsaturated fatty acid content in blood may lower the risk of small brain infarcts and other brain abnormalities in the elderly. The study was published in Journal of the American Heart Association… Read & Research Alzheimer’s More

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People who carry a genetic mutation associated with Alzheimer’s disease may develop the disease three years earlier than expected, according to a new study from Keck Medicine of the University of Southern California (USC)… Read & Research Alzheimer’s More

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Johns Hopkins researchers say that by measuring levels of certain proteins in cerebrospinal fluid (CSF), they can predict when people will develop the cognitive impairment associated with Alzheimer’s disease years before the first symptoms of memory loss appear… Read & Research Alzheimer’s More

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Johns Hopkins scientists have developed new drugs that – at least in a laboratory dish – appear to halt the brain-destroying impact of a genetic mutation at work in some forms of two incurable diseases, amyotrophic lateral sclerosis (ALS) and dementia… Read & Research Alzheimer’s More

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A Johns Hopkins-led analysis of data previously gathered on more than 3,000 elderly Americans strongly suggests that taking certain blood pressure medications to control blood pressure may reduce the risk of dementia due to Alzheimer’s disease (AD)… Read & Research Alzheimer’s More

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Scientists in Loughborough and Indonesia have developed a new soy-based flour product they hope will improve memory in older age and reduce the risk of dementia. The flour originates from tempe – a fermented soy-based product similar to tofu used widely in Asian cooking… Read & Research Alzheimer’s More

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Elderly people suffering from hardening of the arteries are more likely to have beta-amyloid plaques in the brain – an indication of Alzheimer’s disease, according to a study published in the journal Neurology. According to the National Institute on Aging, plaques form in the spaces between the brain’s nerve cells Read & Research Alzheimer’s More

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Scientists at Rice University are enhancing the natural antioxidant properties of an element found in a car’s catalytic converter to make it useful for medical applications. Rice chemist Vicki Colvin led a team that created small, uniform spheres of cerium oxide and gave them a thin coating of fatty oleic Read & Research Alzheimer’s More

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New research led by Marco Prado, PhD, of Western University has identified a pathway used by the brain to try to protect itself from toxicity that occurs with Alzheimer’s disease (AD). Prado and his colleagues at the Robarts Research Institute and at the A.C. Camargo Cancer Center in Brazil have Read & Research Alzheimer’s More

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New research illuminates definitive brain alterations in troops with Gulf War Illness (GWI) thought to result from the exposure to neurotoxic chemicals, including sarin gas, during the first Persian Gulf War. “More than 250,000 troops, or approximately 25% of those deployed during the first Persian Gulf War, have been diagnosed Read & Research Alzheimer’s More

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Despite the common fear that those annoying tip-of-the-tongue moments are signals of age-related memory decline, the two phenomena appear to be independent, according to findings published in Psychological Science, a journal of the Association for Psychological Science… Read & Research Alzheimer’s More

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Mayo Clinic researchers have found a surprising occupational hazard for teachers: progressive speech and language disorders. The research, recently published in the American Journal of Alzheimer’s Disease & Other Dementias, found that people with speech and language disorders are about 3.5 times more likely to be teachers than patients with Read & Research Alzheimer’s More

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A protein that is increased by endurance exercise has been isolated and given to non-exercising mice, in which it turned on genes that promote brain health and encourage the growth of new nerves involved in learning and memory, report scientists from Dana-Farber Cancer Institute and Harvard Medical School… Read & Research Alzheimer’s More

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Research has shown that exercise is good for the brain. Now investigators have identified a molecule called irisin that is produced in the brain during endurance exercise and has neuroprotective effects. Researchers were able to artificially increase the levels of irisin in the blood to activate genes involved in learning Read & Research Alzheimer’s More

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