Archive for January, 2014

Researchers at the Hebrew University of Jerusalem have created a molecule that could potentially lower diabetic patients’ higher risk of developing dementia or Alzheimer’s disease.Recent studies indicate that high levels of sugar in the blood in diabetics and non-diabetics are a risk factor for the development of dementia, impaired cognition, Read & Research Alzheimer’s More

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New research suggests that older women who have both high estrogen levels and diabetes have a significantly higher risk of dementia, compared with older women who do not have these combined conditions. This is according to a study published online in Neurology. Read & Research Alzheimer’s More

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The controversial pesticide DDT was banned in the US in 1972 but is still used in the agricultural industries of some countries. Now, a study published in the Journal of the American Medical Association Neurology has found a link between having levels of a DDT byproduct in the blood and Read & Research Alzheimer’s More

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Increased inflammation following an infection impairs the brain’s ability to form spatial memories – according to new research. The impairment results from a decrease in glucose metabolism in the brain’s memory centre, disrupting the neural circuits involved in learning and memory.Inflammation has long been linked to disorders of memory like Read & Research Alzheimer’s More

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EnVivo Pharmaceuticals, a company dedicated to developing a broad range of novel therapies for central nervous system (CNS) diseases, has announced it has initiated COGNITIV AD, a Phase 3 clinical program evaluating its novel alpha-7 (α7) potentiator, encenicline-hydrochloride (EVP-6124), in patients with Alzheimer’s disease (AD). Read & Research Alzheimer’s More

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Animate, inanimate, but also social"> Animate, inanimate, but also social

Posted January 28, 2014 By FuckAlzheimers

For our brain, animate and inanimate objects belong to different categories and any information about them is stored and processed by different networks. A study by Raffaella Rumiati from SISSA, Andrea Carnaghi from the University of Trieste, and others shows that there is also another category that is functionally distinct Read & Research Alzheimer’s More

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Scientists from the Florida campus of The Scripps Research Institute have identified a critical regulator of a molecule deeply involved in the progression of Alzheimer’s disease. Read & Research Alzheimer’s More

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New research findings indicate that an early onset of dietary treatment may slow down the progression of Alzheimer’s disease. The study was conducted on mice, and the results will be published in the Journal of Nutritional Biochemistry. Read & Research Alzheimer’s More

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Men are frequently accused of forgetting birthdays, wedding anniversaries, and even something as simple as taking the trash out. But they have developed this stigma for a reason, a new study suggest – it found that men are more forgetful than women, regardless of their age.The research team, led by Read & Research Alzheimer’s More

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We are all familiar with the saying “older but wiser.” And new research may prove this to be true. A new study published in the journal Topics in Cognitive Science suggests that as we age, our brain functions slow down as a result of greater experience, not because of cognitive Read & Research Alzheimer’s More

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A new study in the New England Journal of Medicine documents the high-profile failure of a promising drug, bapineuzumab, to slow cognitive decline in dementia patients. Dr. Stephen Salloway, the study’s lead author, says researchers have learned key lessons that they are eager to apply in new attempts to find Read & Research Alzheimer’s More

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Structural biologists at Cold Spring Harbor Laboratory (CSHL) and collaborators at Emory University have obtained important scientific results likely to advance efforts to develop new drugs targeting NMDA receptors in the brain. Read & Research Alzheimer’s More

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Anavex Life Sciences Corp. has announced that a publication in the current issue of scientific journal Neuropathology potentially extends the opportunity for ANAVEX PLUS to additional neurodegenerative diseases beyond Alzheimer’s. Read & Research Alzheimer’s More

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How aging affects communication between neurons is not well understood, a gap that makes it more difficult to treat a range of disorders, including Alzheimer’s and Parkinson’s disease. Read & Research Alzheimer’s More

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Scientists have discovered the use of a simple single-celled amoeba to understand the function of human proteins in causing Alzheimer’s disease. Read & Research Alzheimer’s More

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Alzheimer’s Society and Alzheimer’s Drug Discovery Foundation (ADDF) are offering up to $1.5 million for new research projects with potential to speed up the development of treatments for Alzheimer’s disease and other types of dementia. The international collaboration could help make the hope of finding effective dementia treatments within the Read & Research Alzheimer’s More

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Among the myriad changes that accompany aging, shrinking brain volume can be a worrying one. A normal part of growing older, it can also be a sign of Alzheimer’s disease. But the good news is that a recent study suggests people with higher levels of omega-3 fatty acids have larger Read & Research Alzheimer’s More

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A contest for the best technique of intracellular particle tracking (simultaneous tracking of the motions of hundreds and thousands of intracellular organelles, virions and even individual molecules), that is an important issue in cellular biology and has applications in search for appropriate medicines against certain diseases (including Parkinson’s and Alzheimer’s Read & Research Alzheimer’s More

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Alzheimer’s disease can reach epidemic range in the coming decades, by the increasing average age of society.There are two key issues for Alzheimer’s disease: there is currently no effective treatment and it has been described very few associated genetic changes (mutations) which reduces the number of targets for future therapies. Read & Research Alzheimer’s More

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New research from David Westaway, PhD, of the University of Alberta and Jiri Safar, PhD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that may help keep deadly neurological diseases in check for months or years. Read & Research Alzheimer’s More

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Autophagy - or how cells tidy up"> Autophagy - or how cells tidy up

Posted January 22, 2014 By FuckAlzheimers

“Bang – and the dirt is gone!” There are many commercials for products that claim to make the unpopular process of cleaning up easier. But it’s not only our surroundings that need to be kept clean. Even our cells need to tidy up. Read & Research Alzheimer’s More

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Vitamin D is known to benefit our health by regulating the amount of calcium and phosphate in the body – which helps keep our bones and teeth healthy. But new research suggests that for people with Parkinson’s disease, the vitamin may help prevent or delay the onset of cognitive impairment Read & Research Alzheimer’s More

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At the heart of brain diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer’s disease, and Parkinson’s disease is protein misfolding, in which distorted proteins are unable to perform their normal functions. At present, there is no known way to reverse protein misfolding.But James Shorter, Ph.D. Read & Research Alzheimer’s More

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The structure of the human brain is complex, reminiscent of a circuit diagram with countless connections. But what role does this architecture play in the functioning of the brain? Read & Research Alzheimer’s More

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Cleveland Clinic researchers have identified a protein in the brain that plays a critical role in the memory loss seen in Alzheimer’s patients, according to a study to be published in the journal Nature Neuroscience and posted online nowy.The protein – Neuroligin-1 (NLGN1) – is known to be involved in Read & Research Alzheimer’s More

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Delirium in older patients in an emergency room setting can foretell other health issues. But according to a new study published in the Annals of Emergency Medicine, the condition is frequently overlooked because of a lack of screening tools in emergency departments. Read & Research Alzheimer’s More

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The presence of a gene variant in people with mild cognitive impairment (MCI) is associated with accelerated rates of brain atrophy, according to a new study published online in the journal Radiology.The study focused on the gene apolipoprotein E (APOE), the most important genetic factor known in non-familial Alzheimer’s disease Read & Research Alzheimer’s More

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Caffeine enhances memory"> Caffeine enhances memory

Posted January 15, 2014 By FuckAlzheimers

For some, it’s the tradition of steeping tealeaves to brew the perfect cup of tea. For others, it’s the morning shuffle to a coffee maker for a hot jolt of java. Then there are those who like their wake up with the kind of snap and a fizz usually found Read & Research Alzheimer’s More

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Anavex Life Sciences Corp. has announced that they have established an agreement with The Roskamp Institute for the clinical development of ANAVEX PLUS, a new combination drug of ANAVEX 2-73 and donepezil (Aricept

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New research, led by Rensselaer Polytechnic Institute researcher Chunyu Wang, has solved one mystery in the development of Familial Alzheimer’s Disease (FAD), a genetic variant of the disease that affects a small fraction of the Alzheimer’s population. Read & Research Alzheimer’s More

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