Researchers at the Hebrew University of Jerusalem have created a molecule that could potentially lower diabetic patients’ higher risk of developing dementia or Alzheimer’s disease.Recent studies indicate that high levels of sugar in the blood in diabetics and non-diabetics are a risk factor for the development of dementia, impaired cognition, Read & Research Alzheimer’s More
Archive for January, 2014
Protecting the brain from detrimental effects linked to diabetes and high blood sugar"> Protecting the brain from detrimental effects linked to diabetes and high blood sugar
Posted January 31, 2014 By FuckAlzheimersDiabetes and high estrogen levels raise dementia risk for women"> Diabetes and high estrogen levels raise dementia risk for women
Posted January 30, 2014 By FuckAlzheimersNew research suggests that older women who have both high estrogen levels and diabetes have a significantly higher risk of dementia, compared with older women who do not have these combined conditions. This is according to a study published online in Neurology. Read & Research Alzheimer’s More
A byproduct of the pesticide DDT increases risk of Alzheimer's"> A byproduct of the pesticide DDT increases risk of Alzheimer's
Posted January 28, 2014 By FuckAlzheimersThe controversial pesticide DDT was banned in the US in 1972 but is still used in the agricultural industries of some countries. Now, a study published in the Journal of the American Medical Association Neurology has found a link between having levels of a DDT byproduct in the blood and Read & Research Alzheimer’s More
Our ability to form spatial memories is damaged by infections"> Our ability to form spatial memories is damaged by infections
Posted January 28, 2014 By FuckAlzheimersIncreased inflammation following an infection impairs the brain’s ability to form spatial memories – according to new research. The impairment results from a decrease in glucose metabolism in the brain’s memory centre, disrupting the neural circuits involved in learning and memory.Inflammation has long been linked to disorders of memory like Read & Research Alzheimer’s More
EnVivo Pharmaceuticals initiates COGNITIV AD, a Phase 3 clinical trial program of encenicline (EVP-6124) in Alzheimer's disease"> EnVivo Pharmaceuticals initiates COGNITIV AD, a Phase 3 clinical trial program of encenicline (EVP-6124) in Alzheimer's disease
Posted January 28, 2014 By FuckAlzheimersEnVivo Pharmaceuticals, a company dedicated to developing a broad range of novel therapies for central nervous system (CNS) diseases, has announced it has initiated COGNITIV AD, a Phase 3 clinical program evaluating its novel alpha-7 (α7) potentiator, encenicline-hydrochloride (EVP-6124), in patients with Alzheimer’s disease (AD). Read & Research Alzheimer’s More
Animate, inanimate, but also social"> Animate, inanimate, but also social
Posted January 28, 2014 By FuckAlzheimersFor our brain, animate and inanimate objects belong to different categories and any information about them is stored and processed by different networks. A study by Raffaella Rumiati from SISSA, Andrea Carnaghi from the University of Trieste, and others shows that there is also another category that is functionally distinct Read & Research Alzheimer’s More
Scripps Florida scientists find regulator of amyloid plaque buildup in Alzheimer's disease"> Scripps Florida scientists find regulator of amyloid plaque buildup in Alzheimer's disease
Posted January 27, 2014 By FuckAlzheimersScientists from the Florida campus of The Scripps Research Institute have identified a critical regulator of a molecule deeply involved in the progression of Alzheimer’s disease. Read & Research Alzheimer’s More
Dietary treatment shows potential in a mouse model of Alzheimer's disease"> Dietary treatment shows potential in a mouse model of Alzheimer's disease
Posted January 27, 2014 By FuckAlzheimersNew research findings indicate that an early onset of dietary treatment may slow down the progression of Alzheimer’s disease. The study was conducted on mice, and the results will be published in the Journal of Nutritional Biochemistry. Read & Research Alzheimer’s More
Men are more forgetful than women, study shows"> Men are more forgetful than women, study shows
Posted January 26, 2014 By FuckAlzheimersMen are frequently accused of forgetting birthdays, wedding anniversaries, and even something as simple as taking the trash out. But they have developed this stigma for a reason, a new study suggest – it found that men are more forgetful than women, regardless of their age.The research team, led by Read & Research Alzheimer’s More
Greater experience causes older brains to slow down, study shows"> Greater experience causes older brains to slow down, study shows
Posted January 26, 2014 By FuckAlzheimersWe are all familiar with the saying “older but wiser.” And new research may prove this to be true. A new study published in the journal Topics in Cognitive Science suggests that as we age, our brain functions slow down as a result of greater experience, not because of cognitive Read & Research Alzheimer’s More
Alzheimer's trial disappointing but yields new ideas"> Alzheimer's trial disappointing but yields new ideas
Posted January 24, 2014 By FuckAlzheimersA new study in the New England Journal of Medicine documents the high-profile failure of a promising drug, bapineuzumab, to slow cognitive decline in dementia patients. Dr. Stephen Salloway, the study’s lead author, says researchers have learned key lessons that they are eager to apply in new attempts to find Read & Research Alzheimer’s More
Blocking NMDA receptors to limit neurotoxicity"> Blocking NMDA receptors to limit neurotoxicity
Posted January 24, 2014 By FuckAlzheimersStructural biologists at Cold Spring Harbor Laboratory (CSHL) and collaborators at Emory University have obtained important scientific results likely to advance efforts to develop new drugs targeting NMDA receptors in the brain. Read & Research Alzheimer’s More
Sigma-1 receptor implicated in cell survival of rare neurodegenerative diseases"> Sigma-1 receptor implicated in cell survival of rare neurodegenerative diseases
Posted January 24, 2014 By FuckAlzheimersAnavex Life Sciences Corp. has announced that a publication in the current issue of scientific journal Neuropathology potentially extends the opportunity for ANAVEX PLUS to additional neurodegenerative diseases beyond Alzheimer’s. Read & Research Alzheimer’s More
Scripps Florida scientists offer new insight into neuron changes brought about by aging"> Scripps Florida scientists offer new insight into neuron changes brought about by aging
Posted January 24, 2014 By FuckAlzheimersHow aging affects communication between neurons is not well understood, a gap that makes it more difficult to treat a range of disorders, including Alzheimer’s and Parkinson’s disease. Read & Research Alzheimer’s More
Researchers discover a simple amoeba holds the key to better treatment for Alzheimer's disease"> Researchers discover a simple amoeba holds the key to better treatment for Alzheimer's disease
Posted January 24, 2014 By FuckAlzheimersScientists have discovered the use of a simple single-celled amoeba to understand the function of human proteins in causing Alzheimer’s disease. Read & Research Alzheimer’s More
New global partnership aims to accelerate dementia drug discovery"> New global partnership aims to accelerate dementia drug discovery
Posted January 24, 2014 By FuckAlzheimersAlzheimer’s Society and Alzheimer’s Drug Discovery Foundation (ADDF) are offering up to $1.5 million for new research projects with potential to speed up the development of treatments for Alzheimer’s disease and other types of dementia. The international collaboration could help make the hope of finding effective dementia treatments within the Read & Research Alzheimer’s More
Alzheimer's defense: omega-3s linked to larger brain volume"> Alzheimer's defense: omega-3s linked to larger brain volume
Posted January 23, 2014 By FuckAlzheimersAmong the myriad changes that accompany aging, shrinking brain volume can be a worrying one. A normal part of growing older, it can also be a sign of Alzheimer’s disease. But the good news is that a recent study suggests people with higher levels of omega-3 fatty acids have larger Read & Research Alzheimer’s More
A contest of scientific techniques for methods of particle tracking"> A contest of scientific techniques for methods of particle tracking
Posted January 23, 2014 By FuckAlzheimersA contest for the best technique of intracellular particle tracking (simultaneous tracking of the motions of hundreds and thousands of intracellular organelles, virions and even individual molecules), that is an important issue in cellular biology and has applications in search for appropriate medicines against certain diseases (including Parkinson’s and Alzheimer’s Read & Research Alzheimer’s More
Epigenetic lesion discovered in the hippocampus of Alzheimer's patients"> Epigenetic lesion discovered in the hippocampus of Alzheimer's patients
Posted January 22, 2014 By FuckAlzheimersAlzheimer’s disease can reach epidemic range in the coming decades, by the increasing average age of society.There are two key issues for Alzheimer’s disease: there is currently no effective treatment and it has been described very few associated genetic changes (mutations) which reduces the number of targets for future therapies. Read & Research Alzheimer’s More
Researchers hope to keep deadly brain diseases in check following prion discovery"> Researchers hope to keep deadly brain diseases in check following prion discovery
Posted January 22, 2014 By FuckAlzheimersNew research from David Westaway, PhD, of the University of Alberta and Jiri Safar, PhD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that may help keep deadly neurological diseases in check for months or years. Read & Research Alzheimer’s More
Autophagy - or how cells tidy up"> Autophagy - or how cells tidy up
Posted January 22, 2014 By FuckAlzheimers“Bang – and the dirt is gone!” There are many commercials for products that claim to make the unpopular process of cleaning up easier. But it’s not only our surroundings that need to be kept clean. Even our cells need to tidy up. Read & Research Alzheimer’s More
Vitamin D may prevent cognitive impairment in Parkinson's patients"> Vitamin D may prevent cognitive impairment in Parkinson's patients
Posted January 20, 2014 By FuckAlzheimersVitamin D is known to benefit our health by regulating the amount of calcium and phosphate in the body – which helps keep our bones and teeth healthy. But new research suggests that for people with Parkinson’s disease, the vitamin may help prevent or delay the onset of cognitive impairment Read & Research Alzheimer’s More
Misfolded molecules unravelled using 'reprogrammed' yeast protein; implications for new brain disease therapies"> Misfolded molecules unravelled using 'reprogrammed' yeast protein; implications for new brain disease therapies
Posted January 20, 2014 By FuckAlzheimersAt the heart of brain diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer’s disease, and Parkinson’s disease is protein misfolding, in which distorted proteins are unable to perform their normal functions. At present, there is no known way to reverse protein misfolding.But James Shorter, Ph.D. Read & Research Alzheimer’s More
How the architecture of the brain shapes its functioning has implications for Alzheimer's, schizophrenia"> How the architecture of the brain shapes its functioning has implications for Alzheimer's, schizophrenia
Posted January 20, 2014 By FuckAlzheimersThe structure of the human brain is complex, reminiscent of a circuit diagram with countless connections. But what role does this architecture play in the functioning of the brain? Read & Research Alzheimer’s More
Study uncovers role of Neuroligin-1 protein in Alzheimer's-related memory loss"> Study uncovers role of Neuroligin-1 protein in Alzheimer's-related memory loss
Posted January 20, 2014 By FuckAlzheimersCleveland Clinic researchers have identified a protein in the brain that plays a critical role in the memory loss seen in Alzheimer’s patients, according to a study to be published in the journal Nature Neuroscience and posted online nowy.The protein – Neuroligin-1 (NLGN1) – is known to be involved in Read & Research Alzheimer’s More
Delirium screening lacking in the emergency department"> Delirium screening lacking in the emergency department
Posted January 17, 2014 By FuckAlzheimersDelirium in older patients in an emergency room setting can foretell other health issues. But according to a new study published in the Annals of Emergency Medicine, the condition is frequently overlooked because of a lack of screening tools in emergency departments. Read & Research Alzheimer’s More
Association between gene variation and brain atrophy in mild cognitive impairment"> Association between gene variation and brain atrophy in mild cognitive impairment
Posted January 16, 2014 By FuckAlzheimersThe presence of a gene variant in people with mild cognitive impairment (MCI) is associated with accelerated rates of brain atrophy, according to a new study published online in the journal Radiology.The study focused on the gene apolipoprotein E (APOE), the most important genetic factor known in non-familial Alzheimer’s disease Read & Research Alzheimer’s More
Caffeine enhances memory"> Caffeine enhances memory
Posted January 15, 2014 By FuckAlzheimersFor some, it’s the tradition of steeping tealeaves to brew the perfect cup of tea. For others, it’s the morning shuffle to a coffee maker for a hot jolt of java. Then there are those who like their wake up with the kind of snap and a fizz usually found Read & Research Alzheimer’s More
Anavex agreement with The Roskamp Institute to advance the clinical development of ANAVEX PLUS"> Anavex agreement with The Roskamp Institute to advance the clinical development of ANAVEX PLUS
Posted January 15, 2014 By FuckAlzheimersAnavex Life Sciences Corp. has announced that they have established an agreement with The Roskamp Institute for the clinical development of ANAVEX PLUS, a new combination drug of ANAVEX 2-73 and donepezil (Aricept
Research reveals the mechanism of genetic mutations known to cause familial Alzheimer's disease"> Research reveals the mechanism of genetic mutations known to cause familial Alzheimer's disease
Posted January 14, 2014 By FuckAlzheimersNew research, led by Rensselaer Polytechnic Institute researcher Chunyu Wang, has solved one mystery in the development of Familial Alzheimer’s Disease (FAD), a genetic variant of the disease that affects a small fraction of the Alzheimer’s population. Read & Research Alzheimer’s More