Neuropathologic assessment is the current “gold standard” for evaluating the Alzheimer’s disease (AD), but there is no consensus on the methods used. Read & Research Alzheimer’s More
Archive for August, 2015
Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease"> Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease
Posted August 29, 2015 ByBlast traumatic brain injury–induced cognitive deficits are attenuated by preinjury or postinjury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4"> Blast traumatic brain injury–induced cognitive deficits are attenuated by preinjury or postinjury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4
Posted August 29, 2015 ByBlast traumatic brain injury (B-TBI) affects military and civilian personnel. Presently, there are no approved drugs for blast brain injury. Read & Research Alzheimer’s More
Future Science OA explores current research into protein misfolding diseases"> Future Science OA explores current research into protein misfolding diseases
Posted August 28, 2015 BySpecial issue of Future Science OA examines amyloid aggregation, the causes of protein misfolding diseases, and the future of therapyFuture Science Group (FSG) today announced the publication of… Read & Research Alzheimer’s More
Fat deposits in brain may hasten Alzheimer's disease"> Fat deposits in brain may hasten Alzheimer's disease
Posted August 28, 2015 ByNew research suggests that abnormal fat deposits found in the brains of people who died from Alzheimer’s disease could trigger or accelerate the condition. Read & Research Alzheimer’s More
Surprised? Cholinergic neurons send broadcasts enabling us to learn from the unexpected"> Surprised? Cholinergic neurons send broadcasts enabling us to learn from the unexpected
Posted August 28, 2015 ByWhen a large combat unit, widely dispersed in dense jungle, goes to battle, no single soldier knows precisely how his actions are affecting the unit’s success or failure. Read & Research Alzheimer’s More
Mystery of polar bear Knut's disease finally solved"> Mystery of polar bear Knut's disease finally solved
Posted August 27, 2015 ByThe animal suffered from an autoimmune disease previously known only in humansKnut, the famous polar bear of the Berlin Zoological Garden (Germany) died of encephalitis, as diagnosed soon after… Read & Research Alzheimer’s More
Jammed up cellular highways may initiate dementia and ALS"> Jammed up cellular highways may initiate dementia and ALS
Posted August 27, 2015 ByMolecular therapy partially relieves havoc wreaked by gene mutation in human and fly cellsNeurons, red, created from ALS patients bearing the C9orf72 mutation, show clumps of the RanGAP… Read & Research Alzheimer’s More
Neurodegenerative disease clogs nuclear pores"> Neurodegenerative disease clogs nuclear pores
Posted August 27, 2015 ByHoward Hughes Medical Institute (HHMI) scientists have discovered how the most common genetic defect in amyotrophic lateral sclerosis kills nerve cells. Read & Research Alzheimer’s More
Batting practice in the genome"> Batting practice in the genome
Posted August 26, 2015 ByIn the biochemical game of genetics, it was thought that the proteins controlling gene regulation in animals were either spectators or players. Read & Research Alzheimer’s More
Omega-3 supplements, physical activity fail to show effect against cognitive decline"> Omega-3 supplements, physical activity fail to show effect against cognitive decline
Posted August 26, 2015 ByNew research fails to show a benefit from exercise or dietary supplementation on levels of cognitive brain health, but experts say lifestyle factors should not be written off. Read & Research Alzheimer’s More
Glitter from silver lights up Alzheimer's dark secrets"> Glitter from silver lights up Alzheimer's dark secrets
Posted August 26, 2015 ByScientists have caught a glimpse of the elusive toxic form of the Alzheimer’s molecule, during its attempt to bore into the outer covering of a cell decoy, using a new method involving laser light… Read & Research Alzheimer’s More
The Global Alzheimer's Association Interactive Network"> The Global Alzheimer's Association Interactive Network
Posted August 25, 2015 ByThe Global Alzheimer’s Association Interactive Network (GAAIN) is consolidating the efforts of independent Alzheimer’s disease data repositories around the world with the goals of revealing more insights into the causes of Alzheimer’s disease, improving treatments, and designing preventative measures that delay the onset of physical symptoms. Read & Research Alzheimer’s More
Waterford research on Alzheimer's disease suggests that measuring macular pigment offers potential as a biomarker of cognitive health"> Waterford research on Alzheimer's disease suggests that measuring macular pigment offers potential as a biomarker of cognitive health
Posted August 25, 2015 ByResults to be showcased internationally in the Journal of Alzheimer’s DiseaseOngoing European Research Council-funded research at Waterford Institute of Technology’s (WIT) Macular Pigment… Read & Research Alzheimer’s More
Scientists show how exposure to brief trauma and sudden sounds form lasting memories"> Scientists show how exposure to brief trauma and sudden sounds form lasting memories
Posted August 25, 2015 ByStudy may speed improved treatments for hearing loss and symptoms of PTSDResearchers at NYU Langone Medical Center have found how even brief exposure to sudden sounds or mild trauma can form… Read & Research Alzheimer’s More
Nine risk factors may contribute to two thirds of Alzheimer's cases worldwide"> Nine risk factors may contribute to two thirds of Alzheimer's cases worldwide
Posted August 21, 2015 ByNine potentially modifiable risk factors may contribute to up to two thirds of Alzheimer’s disease cases worldwide, suggests an analysis of the available evidence, published online in the Journal… Read & Research Alzheimer’s More
Levels of dementia may be stabilizing, says report"> Levels of dementia may be stabilizing, says report
Posted August 21, 2015 ByThe rise of dementia that was previously predicted may be false after researchers discover the number of people with the condition is stabilizing in some countries. Read & Research Alzheimer’s More
'Stress hormone' levels in saliva could pinpoint seniors with cognitive decline"> 'Stress hormone' levels in saliva could pinpoint seniors with cognitive decline
Posted August 20, 2015 ByResearchers found older adults with high levels of the ‘stress hormone’ cortisol in their saliva had smaller brain volume and poorer memory and thinking skills. Read & Research Alzheimer’s More
New insights in pathological mechanism that causes dysfunctional synapses"> New insights in pathological mechanism that causes dysfunctional synapses
Posted August 20, 2015 ByGenetic analysis of human patients has shown that mutations in genes involved in synaptic communication can drive neuropsychiatric and neurological diseases such as autism spectrum disorder and… Read & Research Alzheimer’s More
Massachusetts Alzheimer's Disease Research Center: Progress and challenges"> Massachusetts Alzheimer's Disease Research Center: Progress and challenges
Posted August 19, 2015 ByOn September 19, 2014, the Massachusetts Alzheimer’s Disease Research Center (ADRC) held a daylong scientific symposium to celebrate 30 years of research productivity. It was a time to reflect on past accomplishments and to anticipate future directions in research and treatment. The presentations summarized in this article point to advances in the Read & Research Alzheimer’s More
Scientist: Most complete human brain model to date is a 'brain changer'"> Scientist: Most complete human brain model to date is a 'brain changer'
Posted August 19, 2015 ByOnce licensed, model likely to accelerate study of Alzheimer’s, autism, moreScientists at The Ohio State University have developed a nearly complete human brain in a dish that equals the brain… Read & Research Alzheimer’s More
A newly discovered molecular feedback process may protect the brain against Alzheimer's"> A newly discovered molecular feedback process may protect the brain against Alzheimer's
Posted August 19, 2015 ByIt is a hallmark of Alzheimer’s disease: Toxic protein fragments known as amyloid-β clumped together between neurons in a person’s brain. Read & Research Alzheimer’s More
How others see our identity depends on moral traits, not memory"> How others see our identity depends on moral traits, not memory
Posted August 18, 2015 ByWe may view our memory as being essential to who we are, but new findings suggest that others consider our moral traits to be the core component of our identity. Read & Research Alzheimer’s More
Scientists uncover nuclear process in the brain that may affect disease"> Scientists uncover nuclear process in the brain that may affect disease
Posted August 18, 2015 ByNIH-funded study highlights the possible role of glial brain cells in neurological disordersEvery brain cell has a nucleus, or a central command station. Read & Research Alzheimer’s More
Researchers pinpoint where the human brain stores time and place of memories"> Researchers pinpoint where the human brain stores time and place of memories
Posted August 18, 2015 ByUsing a smartphone app and fMRI, researchers from Ohio State University have discovered where the human brain records the time and place of memories. Read & Research Alzheimer’s More
Can your brain control how it loses control?"> Can your brain control how it loses control?
Posted August 17, 2015 ByA new study may have unlocked understanding of a mysterious part of the brain — with implications for neurodegenerative conditions such as Alzheimer’s. Read & Research Alzheimer’s More
'Brainy' mice raise hope of better treatments for cognitive disorders"> 'Brainy' mice raise hope of better treatments for cognitive disorders
Posted August 14, 2015 ByIt sheds light on the molecular underpinnings of learning and memory and could form the basis for research into new treatments for age-related cognitive decline, cognitive disorders such as… Read & Research Alzheimer’s More
FAU neuroscientist develops new, rapid dementia screening tool that rivals 'gold standard' clinical evaluations"> FAU neuroscientist develops new, rapid dementia screening tool that rivals 'gold standard' clinical evaluations
Posted August 14, 2015 ByDetermining whether or not an individual has dementia and to what degree is a long and laborious process that can take an experienced professional such as a clinician about four to five hours to… Read & Research Alzheimer’s More
Sequestered prion protein takes the good mood away, suggests new hypothesis on depression"> Sequestered prion protein takes the good mood away, suggests new hypothesis on depression
Posted August 14, 2015 ByThe discovery of antidepressant drugs in the 1950s led to the first biochemical hypothesis of depression, known as the monoamine hypothesis. Read & Research Alzheimer’s More
Breakthrough in 'marriage-broker' protein"> Breakthrough in 'marriage-broker' protein
Posted August 13, 2015 ByDiscovery provides new tool for understanding and treating neurodegenerative diseasesScientists at the Montreal Neurological Institute and Hospital -The Neuro, at McGill University and the McGill… Read & Research Alzheimer’s More
Newly discovered brain network recognizes what's new, what's familiar"> Newly discovered brain network recognizes what's new, what's familiar
Posted August 13, 2015 ByNetwork has broad role in memory, learning processes, study suggestsOne of the more heartbreaking realities of Alzheimer’s is the moment when a loved one struggling with the disease no longer… Read & Research Alzheimer’s More