Archive for December, 2015

Three 18F-labeled radiopharmaceuticals have been Food and Drug Administration-approved for the identification of cortical amyloidosis in clinical settings. Although there has been strong debate among professionals as to the ethical and social consequences of disclosing such information, increasing numbers of participants are being recruited into secondary prevention trials for which Read & Research Alzheimer’s More

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Hebrew University Team uses algorithms, apps to understand Alzheimer’s, brain maps. Read & Research Alzheimer’s More

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Two genetic variants previously linked to Alzheimer’s disease have been more specifically tied to brain atrophy that is characteristic of the disease. Read & Research Alzheimer’s More

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What were the top medical developments in 2015? This is MNT’s year-end rundown of the most important and eye-catching news from another year of medicine and medical research. Read & Research Alzheimer’s More

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A drug that boosts activity in the brain’s “garbage disposal” system can decrease levels of toxic proteins associated with Alzheimer’s disease and other neurodegenerative disorders and improve… Read & Research Alzheimer’s More

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Diabetes, smoking, coronary heart disease, and congestive heart failure may increase the risk of premature death for hospitalized individuals and nursing home residents with dementia. Read & Research Alzheimer’s More

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A study of thousands of genes in 146 human brains shows that older people lose some circadian rhythms but develop some new ones, providing insights that could help treat dementia. Read & Research Alzheimer’s More

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Researchers at Western University have published the first study in the world showing a decline in the incidence of dementia at a whole population level, which they believe is connected to the… Read & Research Alzheimer’s More

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Extracellular accumulation of amyloid-β protein and intracellular accumulation of tau in brain tissues have been described in animal models of Alzheimer’s disease (AD) and mechanical stress-based diseases of different mechanisms, such as traumatic brain injury (TBI), arterial hypertension (HTN), and normal pressure hydrocephalus (NPH). Read & Research Alzheimer’s More

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The analysis of cerebrospinal fluid biomarkers gains importance in clinical routine and is effective in substantiating dementia diagnosis in the differential diagnostic context. Read & Research Alzheimer’s More

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Investigators have wondered why the brains of some cognitively-intact elderly individuals have abundant pathology on autopsy or significant amyloid deposition on neuroimaging that are… Read & Research Alzheimer’s More

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Down Read & Research Alzheimer’s More

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A new mouse study shows the activity of specific genes changes when new memories form, supporting the idea that chemical tagging of DNA is the molecular basis of long-term memory. Read & Research Alzheimer’s More

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Interdisciplinary team puts together clues to better sense surface hydrophobicity.Proteins are like a body’s in-house Lego set. Read & Research Alzheimer’s More

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Centenarians show successful aging as they remain active and alert at very old ages. Read & Research Alzheimer’s More

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In a large population-based study of randomly selected participants in Germany, researchers found that participants with anemia, defined as haemoglobin… Read & Research Alzheimer’s More

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For the first time, chronic traumatic encephalopathy (CTE) has been confirmed as a unique disease that can be definitively diagnosed by neuropathological examination of brain tissue. Read & Research Alzheimer’s More

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Alzheimer’s disease (AD) is a complex, multifactorial disease that has reached global epidemic proportions. The challenge remains to fully identify its underlying molecular mechanisms that will enable development of accurate diagnostic tools and therapeutics. Conventional experimental approaches that target individual or small sets of genes or proteins may overlook important Read & Research Alzheimer’s More

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Researchers from Princeton University have identified genes important for age-related cognitive declines in memory in adult worm neurons, which had not been studied previously. Read & Research Alzheimer’s More

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Amyloid diseases such as Parkinson’s, Alzheimer’s and type-2 diabetes pose a particular problem for drug designers because they do not present a clear target structure to aim at. Read & Research Alzheimer’s More

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Researchers have discovered how to diagnose Alzheimer’s disease with more than 82 per cent accuracy by evaluating the interplay between four linguistic factors; and developing automated technology to… Read & Research Alzheimer’s More

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Few recent studies have suggested declining trends in dementia frequency. French cohorts with long follow-up allowed us to explore incidence evolution trends. Read & Research Alzheimer’s More

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Stress appears to contribute to the development of amnestic mild cognitive impairment in older people, increasing the risk for Alzheimer’s disease. Read & Research Alzheimer’s More

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Differences in men’s and women’s brains reflect different approaches to navigation. Men appear to have more effective navigational strategies, with implications for Alzheimer’s. Read & Research Alzheimer’s More

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Playing 3D video games was found to boost memory performance by around 12% in a new study, suggesting such games could help maintain cognitive functioning during aging. Read & Research Alzheimer’s More

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Too many tests at the doctor’s office could cost you more than just dollars. Read & Research Alzheimer’s More

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Researchers found the flavonoid apigenin – found in thyme, parsley and other plants and herbs – boosts formation of human cells and strengthens their connections. Read & Research Alzheimer’s More

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A new epidemiologic study showed that patients with early stage dementia, who had been referred to a specialist, have twice the risk of institutionalization compared to those who are not, according… Read & Research Alzheimer’s More

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A discovery into the mechanisms which lead to degeneration and loss of communication among neuron cells – the cells controlling function in the brain and nervous system – could potentially lead to… Read & Research Alzheimer’s More

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