Archive for February, 2016

Increased longevity also increases risk for age-related dementia.People who reach their 80s without cardiovascular disease are more likely to suffer from the effects of dementia than a heart… Read & Research Alzheimer’s More

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New research demonstrates novel drug discovery paradigm to target the aggregation of the Tau protein linked to the onset of Alzheimer’s and other related neurodegenerative diseasesDementia… Read & Research Alzheimer’s More

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Neurosurgeons at Barrow Neurological Institute in Phoenix are involved with testing the viability of deep brain stimulation (DBS) to treat Alzheimer’s disease, a disorder that currently has few… Read & Research Alzheimer’s More

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For the first time, an international team headed by scientists from the University of Zurich has found a way to specifically inhibit an enzyme that is partly responsible for Alzheimer’s disease. Read & Research Alzheimer’s More

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Epidemiologic studies have demonstrated an association between diabetes and dementia. Insulin signaling within the brain, in particular within the hypothalamus regulates carbohydrate, lipid, and branched chain amino acid (BCAA) metabolism in peripheral organs such as the liver and adipose tissue. We hypothesized that cerebral amyloidosis impairs central nervous system control Read & Research Alzheimer’s More

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Enzymes rarely have one job. So, attempts to shut down the enzyme that causes the hallmarks of Alzheimer’s disease often mean side effects, because these therapies prevent the enzyme from carrying… Read & Research Alzheimer’s More

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Cerebral small vessel disease (CSVD) is a highly prevalent condition associated with diffuse ischemic damage and cognitive dysfunction particularly in executive function and attention. Functional brain imaging studies can reveal mechanisms of cognitive impairment in CSVD, although findings are mixed. Read & Research Alzheimer’s More

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Scientists have now described the engineering of a bright red fluorescent protein-based voltage indicator, providing pathways to understanding complex neurological disorders. Read & Research Alzheimer’s More

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Enzymes rarely have one job. So, attempts to shut down the enzyme that causes the hallmarks of Alzheimer’s disease often mean side effects, because these therapies prevent the enzyme from carrying… Read & Research Alzheimer’s More

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The benefits of mental and physical activity on the aging brain are now well documented. However, the progression of Alzheimer’s disease appears to follow its own rules. Read & Research Alzheimer’s More

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We evaluated the effect of Alzheimer’s disease (AD) susceptibility loci on endophenotypes closely related with AD pathology in patients with mild cognitive impairment (MCI). Read & Research Alzheimer’s More

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UCI mouse study finds dramatic increase in brain plaques when key cells are lacking. Read & Research Alzheimer’s More

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Animal studies suggest greater emphasis for better results and highlight key role of brain system in rebuilding structure and function. Read & Research Alzheimer’s More

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Therapeutic gene transfer to specific brain regions in animal models of Alzheimer’s disease has uncovered multiple potential treatment approaches that deserve to be considered as candidates for… Read & Research Alzheimer’s More

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Accurate estimates of cognitive and clinical decline rates are essential to the design of clinical trials in Alzheimer’s disease (AD) dementia. Read & Research Alzheimer’s More

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Fresh approach identifies genetic risk factors that influence complex human diseases. Read & Research Alzheimer’s More

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Researchers found a drug called MW151 was effective for reducing detrimental brain inflammation in a mouse model of traumatic brain injury by blocking a pro-inflammatory cytokine. Read & Research Alzheimer’s More

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Despite several safe drug therapies available to help smokers quit, three-quarters report relapsing within six months of a quit attempt. Read & Research Alzheimer’s More

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For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. Read & Research Alzheimer’s More

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Eating at least one portion of fish per week helps to reduce a person’s risk of developing Alzheimer’s disease and dementia-related illnesses. Read & Research Alzheimer’s More

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Essential for maintaining cognitive function as a person ages, the tiny locus coeruleus region of the brain is vulnerable to toxins and infection. Read & Research Alzheimer’s More

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Bleeding within the brain, or intracerebral hemorrhage, was associated with a high risk of developing dementia post stroke, according to research presented at the American Stroke Association’s… Read & Research Alzheimer’s More

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The number of persons aged >90 years will grow significantly in coming decades. This group has the highest rates of dementia, most commonly Alzheimer’s disease (AD). Read & Research Alzheimer’s More

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In a study of patients entering the hospital for acute stroke, researchers have increased their understanding of an association between certain types of stroke and the presence of the oral bacteria… Read & Research Alzheimer’s More

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Alzheimer’s disease is the most common cause of senile dementia, and the prevalence is increasing with population aging. Read & Research Alzheimer’s More

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The use of proton pump inhibitors, the popular medications used to treat gastroesophageal reflux and peptic ulcers, may be associated with an increased risk of dementia in a study using data from a… Read & Research Alzheimer’s More

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Being a caregiver for an older adult isn’t easy. A new study suggests that family and unpaid caregivers who provide substantial help with health care were more likely to miss out on valued… Read & Research Alzheimer’s More

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The advantages of speaking a second language – for health and mental ability – came under the spotlight at an event at the AAAS annual meeting in Washington, DC. Read & Research Alzheimer’s More

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A new study suggests the anti-cancer compound bexarotene may not reverse Alzheimer’s disease, but, if given early enough, it could delay its onset. Read & Research Alzheimer’s More

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Researchers have identified a drug that targets the first step in the toxic chain reaction leading to the death of brain cells, suggesting that treatments could be developed to protect against… Read & Research Alzheimer’s More

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