Archive for March, 2016

Dementia will develop in about 80% of patients with Parkinson’s disease, and a new study has found significant variability in brain signaling that could serve as a predictive marker for identifying… Read & Research Alzheimer’s More

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Findings could lead to better cognitive training for those at risk of dementia. Read & Research Alzheimer’s More

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MedUni Vienna researchers have published the results of a clarifying research study on the potential transmissibility of Alzheimer’s disease. Read & Research Alzheimer’s More

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A large, multi-center study led by the UC Davis School of Medicine for the first time has shown that people as young as their 40s have stiffening of the arteries that is associated with subtle… Read & Research Alzheimer’s More

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Sorting-related receptor with A-type repeats (SORLA) is an intracellular sorting receptor in neurons and a major risk factor for Alzheimer disease. Read & Research Alzheimer’s More

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Given the complex neuropathology Alzheimer’s disease (AD), combination therapy may be necessary for effective treatment. However, scientific, pragmatic, regulatory, and business challenges need to be addressed before combination therapy for AD can become a reality. Leaders from academia and industry, along with a former member of the Food and Drug Read & Research Alzheimer’s More

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A transition is a physical move from one location to another with a stay of at least one night. For older adults, especially those with dementia, some transitions may be unavoidable and necessary. Read & Research Alzheimer’s More

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A new study sheds light on a powerful tool that may detect signs of Alzheimer’s disease before patients show any symptoms of cognitive decline: the home computer. Read & Research Alzheimer’s More

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As the discovery of the Alzheimer disease (AD) genes, APP, PSEN1, and PSEN2, in families with autosomal dominant early-onset AD (EOAD), gene discovery in familial EOAD came more or less to a standstill. Only 5% of EOAD patients are carrying a pathogenic mutation in one of the AD genes or Read & Research Alzheimer’s More

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We investigated the change in DNA methylation in peripheral blood CD4+ lymphocytes over time, examined the relation between CD4+ lymphocytes and brain methylation, and compared their associations with AD pathology. Read & Research Alzheimer’s More

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Tau immunotherapy has emerged as a promising approach to clear tau aggregates from the brain. Our previous findings suggest that tau antibodies may act outside and within neurons to promote such clearance. Read & Research Alzheimer’s More

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People with Parkinson’s disease are often prescribed antipsychotic drugs for dementia or psychosis, but these drugs may increase the risk of mortality. Read & Research Alzheimer’s More

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A new analysis based on two long-term aging studies–one of Roman Catholic nuns, the other of Japanese American men–provides what may be the most compelling evidence yet that dementia commonly… Read & Research Alzheimer’s More

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Researchers have created an implantable capsule that produces antibodies that target and destroy beta-amyloid – a protein believed to play a major role in Alzheimer’s development. Read & Research Alzheimer’s More

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Scientists have used optogenetics to retrieve the memories of mice with early Alzheimer’s symptoms, suggesting it may be possible to restore memories in humans with the condition. Read & Research Alzheimer’s More

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Light stimulation of brain cells can recover memories in mice with Alzheimer’s disease-like memory loss, according to new research from the RIKEN-MIT Center for Neural Circuit Genetics. Read & Research Alzheimer’s More

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Rutgers and Stanford scientists develop novel way to inject healthy human nerve cells into the brain. Read & Research Alzheimer’s More

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Gender-specific differences between the levels and structures of proteins present in the white matter and the mitochondria of the brains of men and women suffering from dementia have been revealed… Read & Research Alzheimer’s More

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Traumatic brain injury appears to be related to both increased risk and earlier onset of mild cognitive impairment, UT Southwestern Medical Center researchers report. Read & Research Alzheimer’s More

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The genetics underlying posterior cortical atrophy (PCA), typically a rare variant of Alzheimer’s disease (AD), remain uncertain. Read & Research Alzheimer’s More

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NIH consortium uses big data, team science to uncover complex interplay of factors. Read & Research Alzheimer’s More

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Preventing Alzheimer’s disease through supplementation with natural omega-3 fatty acids.Changes in cognitive function and memory decline form a normal part of aging. Read & Research Alzheimer’s More

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Pure maple syrup research shows promise in the fight against Alzheimer’s disease. Read & Research Alzheimer’s More

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Using a new optical ‘super-resolution’ method, researchers have identified the point at which a protein called alpha-synuclein becomes toxic to brain cells, triggering Parkinson’s. Read & Research Alzheimer’s More

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To meet the challenge of Alzheimer’s disease and other dementias, a concerted effort and long-term economic commitment is needed, according to a new expert report by internationally leading… Read & Research Alzheimer’s More

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The corticobasal syndrome (CBS) constitutes a neurodegenerative disease spectrum with substantial phenotypical or biological heterogeneity, requiring large or multimodal studies to identify its clinico-biological signature while disentangling Alzheimer’s disease (AD)-related from non-AD-related CBS. Read & Research Alzheimer’s More

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Alzheimer’s disease (AD) is among the most significant health care burdens. Disappointing results from clinical trials in late-stage AD persons combined with hopeful results from trials in persons with early-stage suggest that research in the preclinical stage of AD is necessary to define an optimal therapeutic success window. We review Read & Research Alzheimer’s More

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Two small-scale studies into the effects of freeze-dried blueberry powder suggest that the berries could help improve brain function and cognitive performance in some older adults. Read & Research Alzheimer’s More

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New practice guidelines for the diagnosis and treatment of dementia in Australia promise to help frontline health care professionals to improve the quality and consistency of the care they offer… Read & Research Alzheimer’s More

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Put on your dancing shoes. Any kind of exercise appears to boost brain volume and decrease the risk of getting Alzheimer’s disease, says a new study. Read & Research Alzheimer’s More

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