Archive for May, 2016

New research suggests a leaky blood-brain barrier, which normally helps keep the brain healthy, may be a key mechanism in early Alzheimer’s disease. Read & Research Alzheimer’s More

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Chronic pain often goes unnoticed and therefore untreated in patients with cognitive impairments such as dementia. Read & Research Alzheimer’s More

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We estimated the prevalence of microinfarcts and their association with dementia in a cohort of oldest-old participants. Read & Research Alzheimer’s More

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Massive investment and technological advances in the collection of extensive and longitudinal information on thousands of Alzheimer patients results in large amounts of data. These “big-data” databases can potentially advance CNS research and drug development. However, although necessary, they are not sufficient, and we posit that they must be matched Read & Research Alzheimer’s More

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Prion diseases are fatal and incurable neurodegenerative conditions of humans and animals. Yet, how prions kill nerve cells (or neurons) remains unclear. Read & Research Alzheimer’s More

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A new study from Orebro University, published in Science Signaling, shows that heart medication reduces the build-up of plaque in the brain’s blood vessels in mice. Read & Research Alzheimer’s More

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Alzheimer disease (AD) and Parkinson disease (PD) involve tau pathology. Tau is detectable in blood, but its clearance from neuronal cells and the brain is poorly understood. Read & Research Alzheimer’s More

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Breaking research shows that men whose blood cells have lost their Y chromosomes have increased Alzheimer’s risk. Could this explain why men die younger? Read & Research Alzheimer’s More

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Men with blood cells that do not carry the Y chromosome are at greater risk of being diagnosed with Alzheimer’s disease (AD), and this is in addition to an increased risk of death from other… Read & Research Alzheimer’s More

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The Predictors study was designed to predict the length of time to major disease outcomes in Alzheimer’s disease (AD) patients. Here, we describe the development of a new, Predictors 3, cohort. Read & Research Alzheimer’s More

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A biosensor developed by researchers at the National Nanotechnology Laboratory (LNNano) in Campinas, São Paulo State, Brazil, has been proven capable of detecting molecules associated with… Read & Research Alzheimer’s More

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Coprophagia, eating one’s feces, is common in animals but rarely seen in humans. Read & Research Alzheimer’s More

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High blood pressure could significantly raise the risk of developing the second most common form of dementia, according to a new study from The George Institute for Global Health. Read & Research Alzheimer’s More

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A new study by the University of Liverpool’s Institute of Ageing and Chronic Disease has identified food stuffs that can help prevent chronic inflammation that contributes to many leading causes of… Read & Research Alzheimer’s More

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Mouse study shows activity of certain brain cells in rapid eye movement sleep – but not during other sleep phases or wakefulness – is required for normal memory consolidation. Read & Research Alzheimer’s More

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For decades, scientists have fiercely debated whether rapid eye movement (REM) sleep – the phase where dreams appear – is directly involved in memory formation. Read & Research Alzheimer’s More

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The results of preclinical studies by investigators at the Medical University of South Carolina (MUSC) reported in the May 2016 issue of Nature Communications demonstrate that CHOP/GADD153-dependent… Read & Research Alzheimer’s More

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An out of control immune system has been identified as a possible cause of neurodegenerative diseases such as Alzheimer’s. Read & Research Alzheimer’s More

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A new study by SDSU scientists finds that fruit flies could be a model organism for learning the genetic pathways that affect human brain injuries and recovery.Each year, an estimated 1. Read & Research Alzheimer’s More

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“Pentameric quaternary structure of the intracellular domain of serotonin type 3A receptors,” was published in the April issue of Scientific Reports. Along with her research team, Akash Pandhare, Ph. Read & Research Alzheimer’s More

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Successful 1,000-fold enhancement of reaction velocity constants for proteins’ change into toxic substances. Read & Research Alzheimer’s More

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Older adults who engaged in a 3-month course of yoga and meditation showed memory improvements in a new study, suggesting the practices may lower dementia risk. Read & Research Alzheimer’s More

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Rapid growth of the older adult population requires greater epidemiologic characterization of dementia. We developed national prevalence estimates of diagnosed dementia and subtypes in the highest risk U.S. population. Read & Research Alzheimer’s More

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Abnormal brain activity hinders memory replay in the apoE4 mouse model of Alzheimer’s disease. Read & Research Alzheimer’s More

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Two doctors from Danish international pharmaceutical company Lundbeck write about the challenges researchers face in uncovering a much-needed cure for Alzheimer’s. Read & Research Alzheimer’s More

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We estimate the burden of late-onset dementia in the United Kingdom through to 2025 and assess the impact of potential interventions. Read & Research Alzheimer’s More

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Despite studies that claim people with cancer are less likely to develop Alzheimer’s disease–raising the possibility that what triggers cancer also prevents the neurodegenerative disorder–a new… Read & Research Alzheimer’s More

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Studies may provide insight into novel therapeutic approaches targeting formation of tau pathology that drives degeneration. Read & Research Alzheimer’s More

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Researchers from Germany and the USA have identified an important mechanism with which memory switches from recall to memorization mode. Read & Research Alzheimer’s More

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Eating together, providing social support and interaction during meals could help people with dementia avoid dehydration and malnutrition – according to new NIHR-funded research from the University… Read & Research Alzheimer’s More

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