Archive for August, 2016

Study shows blood flow to parts of the brain important for cognitive health – such as the hippocampus – reduces when fit older adults stop exercising. Read & Research Alzheimer’s More

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The tidal wave approaches. In the coming decades, Alzheimer’s disease is projected to exact a devastating economic and emotional toll on society, with patient numbers in the US alone expected to… Read & Research Alzheimer’s More

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Investigation of the conversion rates from normal cognition (NC) to mild cognitive impairment (MCI) is important, as effective early intervention could potentially prevent or substantially delay the onset of dementia. However, reported conversion rates differ across studies and recruitment source. Read & Research Alzheimer’s More

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A novel test that detects abnormal alpha-synuclein protein was found to identify Parkinson’s patients with 95 percent accuracy, researchers report. Read & Research Alzheimer’s More

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Long-term study involving more than 800 World Trade Center Responders shows that post-traumatic stress disorder has strong links with cognitive decline. Read & Research Alzheimer’s More

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Boosting levels of a specific protein in the brain alleviates hallmark features of Alzheimer’s disease in a mouse model of the disorder, according to new research published online in Scientific… Read & Research Alzheimer’s More

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In 2010, Alzheimer’s Disease International presented estimates of the global cost of illness (COI) of dementia. Since then, new studies have been conducted, and the number of people with dementia has increased. Here, we present an update of the global cost estimates. Read & Research Alzheimer’s More

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The Dominantly Inherited Alzheimer Network Trial Unit (DIAN-TU) is an adaptive platform trial testing multiple drugs to slow or prevent the progression of Alzheimer’s disease in autosomal dominant Alzheimer’s disease (ADAD) families. With completion of enrollment of the first two drug arms, the DIAN-TU now plans to add new drugs Read & Research Alzheimer’s More

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Researchers study whether two new drugs can reduce or eliminate protein linked to Alzheimer’s. Read & Research Alzheimer’s More

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A new study suggests that epigenetic changes can alter the abundance of specific channels to control neuronal excitability, which is known to be dysregulated in many brain disorders. Read & Research Alzheimer’s More

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Currently, cognitive impairment of patients diagnosed with Alzheimer’s disease (AD) is measured using the ‘Mini-Mental State Examination’ (MMSE) test, which involves monitoring answers to five… Read & Research Alzheimer’s More

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Neurons in the brain interact by sending each other chemical messages, so-called neurotransmitters. Read & Research Alzheimer’s More

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“Walkable” neighborhoods offer older adults opportunities for activities that may benefit cognition-related biological mechanisms. These have not previously been examined in this context. Read & Research Alzheimer’s More

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In seniors who have experienced cerebrovascular disease, including stroke, calcium supplements may increase the risk of dementia, study finds. Read & Research Alzheimer’s More

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A healthy diet, a healthy BMI, and regular physical activity could reduce the buildup of proteins associated with Alzheimer’s disease, a new study finds. Read & Research Alzheimer’s More

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Researchers reveal a common NSAID called mefenamic acid reversed memory loss in mouse models of Alzheimer’s disease, paving the way for human trials. Read & Research Alzheimer’s More

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The way in which Alzheimer’s brain changes progress is linked to poor control of protein in specific areas of the brain. New research maps these changes. Read & Research Alzheimer’s More

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The underlying pathological mechanisms linking cardiovascular burden to cognitive decline remain unclear. Read & Research Alzheimer’s More

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Cerebrovascular lesions on MRI are common in Alzheimer’s disease (AD) dementia, but less is known about their frequency and impact on dementia with Lewy bodies (DLB). Read & Research Alzheimer’s More

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A new review finds higher adherence to the Mediterranean diet may slow cognitive decline and lower the risk of Alzheimer’s disease. Read & Research Alzheimer’s More

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Many people with mild cognitive impairment (MCI) suffer from concomitant depression or anxiety. Whether MCI increases the risk of future depression or anxiety is unknown. Read & Research Alzheimer’s More

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TREM2 is a lipid-sensing activating receptor on microglia known to be important for Alzheimer’s disease (AD), but whether it plays a beneficial or detrimental role in disease pathogenesis is controversial. Read & Research Alzheimer’s More

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Alzheimer’s disease (AD) progression follows a specific spreading pattern, emphasizing the need to characterize those brain areas that degenerate first. The brainstem’s locus coeruleus (LC) is the first area to develop neurofibrillary changes (neurofibrillary tangles [NFTs]). Read & Research Alzheimer’s More

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Acupuncture may help to improve the subtle memory loss that precedes the development of dementia, otherwise known as mild cognitive impairment, or MCI for short, suggests a review of the available… Read & Research Alzheimer’s More

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The Alzheimer’s Association has announced a $4.3 million research grant to support a new phase of the Dominantly Inherited Alzheimer’s Network Trials Unit (DIAN-TU) known as DIAN-TU Next Generation (NexGen). The award will accelerate testing of potential Alzheimer’s disease (AD) therapies, as well as testing of new diagnostic approaches, in Read & Research Alzheimer’s More

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Acupuncture alone or combined with drug treatment may improve dementia precursor and improve scores on tests used to assess mild cognitive impairment. Read & Research Alzheimer’s More

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A new generation of drugs that prevent cancer and Alzheimer’s could be developed, thanks to research from the University of Warwick. Read & Research Alzheimer’s More

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Iowa State University researchers have identified a protein essential for building memories that appears to predict the progression of memory loss and brain atrophy in Alzheimer’s patients. Read & Research Alzheimer’s More

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An investigation into the relationship between seniors’ weight and risk of Alzheimer’s has revealed that lower weight is linked with elevated disease risk. Read & Research Alzheimer’s More

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A meta-analysis of brain-training studies shows that not all techniques are equal, but speed of processing training reduces dementia risk. Read & Research Alzheimer’s More

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