Study shows blood flow to parts of the brain important for cognitive health – such as the hippocampus – reduces when fit older adults stop exercising. Read & Research Alzheimer’s More
Archive for August, 2016
Brain blood flow reduces when fit older adults stop exercising"> Brain blood flow reduces when fit older adults stop exercising
Posted August 31, 2016 ByCritical protein shows promise for the treatment of Alzheimer's"> Critical protein shows promise for the treatment of Alzheimer's
Posted August 31, 2016 ByThe tidal wave approaches. In the coming decades, Alzheimer’s disease is projected to exact a devastating economic and emotional toll on society, with patient numbers in the US alone expected to… Read & Research Alzheimer’s More
Progression from normal cognition to mild cognitive impairment in a diverse clinic-based and community-based elderly cohort"> Progression from normal cognition to mild cognitive impairment in a diverse clinic-based and community-based elderly cohort
Posted August 30, 2016 ByInvestigation of the conversion rates from normal cognition (NC) to mild cognitive impairment (MCI) is important, as effective early intervention could potentially prevent or substantially delay the onset of dementia. However, reported conversion rates differ across studies and recruitment source. Read & Research Alzheimer’s More
Early Parkinson's diagnosis moves closer with new protein test"> Early Parkinson's diagnosis moves closer with new protein test
Posted August 30, 2016 ByA novel test that detects abnormal alpha-synuclein protein was found to identify Parkinson’s patients with 95 percent accuracy, researchers report. Read & Research Alzheimer’s More
PTSD and cognitive decline linked in 9/11 responders"> PTSD and cognitive decline linked in 9/11 responders
Posted August 30, 2016 ByLong-term study involving more than 800 World Trade Center Responders shows that post-traumatic stress disorder has strong links with cognitive decline. Read & Research Alzheimer’s More
Elevating brain protein allays symptoms of Alzheimer's and improves memory"> Elevating brain protein allays symptoms of Alzheimer's and improves memory
Posted August 30, 2016 ByBoosting levels of a specific protein in the brain alleviates hallmark features of Alzheimer’s disease in a mouse model of the disorder, according to new research published online in Scientific… Read & Research Alzheimer’s More
The worldwide costs of dementia 2015 and comparisons with 2010"> The worldwide costs of dementia 2015 and comparisons with 2010
Posted August 29, 2016 ByIn 2010, Alzheimer’s Disease International presented estimates of the global cost of illness (COI) of dementia. Since then, new studies have been conducted, and the number of people with dementia has increased. Here, we present an update of the global cost estimates. Read & Research Alzheimer’s More
The DIAN-TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model"> The DIAN-TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model
Posted August 29, 2016 ByThe Dominantly Inherited Alzheimer Network Trial Unit (DIAN-TU) is an adaptive platform trial testing multiple drugs to slow or prevent the progression of Alzheimer’s disease in autosomal dominant Alzheimer’s disease (ADAD) families. With completion of enrollment of the first two drug arms, the DIAN-TU now plans to add new drugs Read & Research Alzheimer’s More
Pioneering Alzheimer's prevention study starts enrolling high-risk older adults"> Pioneering Alzheimer's prevention study starts enrolling high-risk older adults
Posted August 26, 2016 ByResearchers study whether two new drugs can reduce or eliminate protein linked to Alzheimer’s. Read & Research Alzheimer’s More
How epigenetics shapes neuronal excitability"> How epigenetics shapes neuronal excitability
Posted August 25, 2016 ByA new study suggests that epigenetic changes can alter the abundance of specific channels to control neuronal excitability, which is known to be dysregulated in many brain disorders. Read & Research Alzheimer’s More
Multivariate analysis improves on cognitive testing in Alzheimer's disease"> Multivariate analysis improves on cognitive testing in Alzheimer's disease
Posted August 25, 2016 ByCurrently, cognitive impairment of patients diagnosed with Alzheimer’s disease (AD) is measured using the ‘Mini-Mental State Examination’ (MMSE) test, which involves monitoring answers to five… Read & Research Alzheimer’s More
Too much activity in one of the brain's key memory regions is bad for your memory and attention"> Too much activity in one of the brain's key memory regions is bad for your memory and attention
Posted August 24, 2016 ByNeurons in the brain interact by sending each other chemical messages, so-called neurotransmitters. Read & Research Alzheimer’s More
Associations of neighborhood environment with brain imaging outcomes in the AIBL cohort"> Associations of neighborhood environment with brain imaging outcomes in the AIBL cohort
Posted August 19, 2016 By“Walkable” neighborhoods offer older adults opportunities for activities that may benefit cognition-related biological mechanisms. These have not previously been examined in this context. Read & Research Alzheimer’s More
Dementia risk increased with calcium supplements in certain women"> Dementia risk increased with calcium supplements in certain women
Posted August 18, 2016 ByIn seniors who have experienced cerebrovascular disease, including stroke, calcium supplements may increase the risk of dementia, study finds. Read & Research Alzheimer’s More
Alzheimer's-causing proteins could be reduced with a healthy diet, exercise"> Alzheimer's-causing proteins could be reduced with a healthy diet, exercise
Posted August 17, 2016 ByA healthy diet, a healthy BMI, and regular physical activity could reduce the buildup of proteins associated with Alzheimer’s disease, a new study finds. Read & Research Alzheimer’s More
Could memory loss be reversed with a common painkiller?"> Could memory loss be reversed with a common painkiller?
Posted August 12, 2016 ByResearchers reveal a common NSAID called mefenamic acid reversed memory loss in mouse models of Alzheimer’s disease, paving the way for human trials. Read & Research Alzheimer’s More
Poor protein control key to Alzheimer's progression"> Poor protein control key to Alzheimer's progression
Posted August 11, 2016 ByThe way in which Alzheimer’s brain changes progress is linked to poor control of protein in specific areas of the brain. New research maps these changes. Read & Research Alzheimer’s More
Mixed brain lesions mediate the association between cardiovascular risk burden and cognitive decline in old age: A population-based study"> Mixed brain lesions mediate the association between cardiovascular risk burden and cognitive decline in old age: A population-based study
Posted August 10, 2016 ByThe underlying pathological mechanisms linking cardiovascular burden to cognitive decline remain unclear. Read & Research Alzheimer’s More
An investigation of cerebrovascular lesions in dementia with Lewy bodies compared to Alzheimer's disease"> An investigation of cerebrovascular lesions in dementia with Lewy bodies compared to Alzheimer's disease
Posted August 10, 2016 ByCerebrovascular lesions on MRI are common in Alzheimer’s disease (AD) dementia, but less is known about their frequency and impact on dementia with Lewy bodies (DLB). Read & Research Alzheimer’s More
Mediterranean diet may slow cognitive decline, prevent Alzheimer's"> Mediterranean diet may slow cognitive decline, prevent Alzheimer's
Posted August 10, 2016 ByA new review finds higher adherence to the Mediterranean diet may slow cognitive decline and lower the risk of Alzheimer’s disease. Read & Research Alzheimer’s More
Mild cognitive impairment and risk of depression and anxiety: a population-based study"> Mild cognitive impairment and risk of depression and anxiety: a population-based study
Posted August 9, 2016 ByMany people with mild cognitive impairment (MCI) suffer from concomitant depression or anxiety. Whether MCI increases the risk of future depression or anxiety is unknown. Read & Research Alzheimer’s More
Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation"> Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation
Posted August 9, 2016 ByTREM2 is a lipid-sensing activating receptor on microglia known to be important for Alzheimer’s disease (AD), but whether it plays a beneficial or detrimental role in disease pathogenesis is controversial. Read & Research Alzheimer’s More
Locus coeruleus volume and cell population changes during Alzheimer's disease progression: A stereological study in human postmortem brains with potential implication for early-stage biomarker discovery"> Locus coeruleus volume and cell population changes during Alzheimer's disease progression: A stereological study in human postmortem brains with potential implication for early-stage biomarker discovery
Posted August 8, 2016 ByAlzheimer’s disease (AD) progression follows a specific spreading pattern, emphasizing the need to characterize those brain areas that degenerate first. The brainstem’s locus coeruleus (LC) is the first area to develop neurofibrillary changes (neurofibrillary tangles [NFTs]). Read & Research Alzheimer’s More
Acupuncture may help to improve dementia precursor - impaired memory"> Acupuncture may help to improve dementia precursor - impaired memory
Posted August 8, 2016 ByAcupuncture may help to improve the subtle memory loss that precedes the development of dementia, otherwise known as mild cognitive impairment, or MCI for short, suggests a review of the available… Read & Research Alzheimer’s More
Alzheimer's Association Update"> Alzheimer's Association Update
Posted August 6, 2016 ByThe Alzheimer’s Association has announced a $4.3 million research grant to support a new phase of the Dominantly Inherited Alzheimer’s Network Trials Unit (DIAN-TU) known as DIAN-TU Next Generation (NexGen). The award will accelerate testing of potential Alzheimer’s disease (AD) therapies, as well as testing of new diagnostic approaches, in Read & Research Alzheimer’s More
Pre-dementia memory loss improved with acupuncture"> Pre-dementia memory loss improved with acupuncture
Posted August 5, 2016 ByAcupuncture alone or combined with drug treatment may improve dementia precursor and improve scores on tests used to assess mild cognitive impairment. Read & Research Alzheimer’s More
Next steps towards preventing cancer and Alzheimer's"> Next steps towards preventing cancer and Alzheimer's
Posted August 5, 2016 ByA new generation of drugs that prevent cancer and Alzheimer’s could be developed, thanks to research from the University of Warwick. Read & Research Alzheimer’s More
ISU study suggests 'use it or lose it' to defend against memory loss"> ISU study suggests 'use it or lose it' to defend against memory loss
Posted August 5, 2016 ByIowa State University researchers have identified a protein essential for building memories that appears to predict the progression of memory loss and brain atrophy in Alzheimer’s patients. Read & Research Alzheimer’s More
Lower BMI, weight loss in later life linked with Alzheimer's"> Lower BMI, weight loss in later life linked with Alzheimer's
Posted August 4, 2016 ByAn investigation into the relationship between seniors’ weight and risk of Alzheimer’s has revealed that lower weight is linked with elevated disease risk. Read & Research Alzheimer’s More
Specific brain-training technique shown to reduce dementia risk"> Specific brain-training technique shown to reduce dementia risk
Posted August 4, 2016 ByA meta-analysis of brain-training studies shows that not all techniques are equal, but speed of processing training reduces dementia risk. Read & Research Alzheimer’s More