Archive for November, 2016

Following the news that Alzheimer’s drug solanezumab has failed clinical trials, we look at whether researchers are on the right track for new treatments Read & Research Alzheimer’s More

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New research tests the effect of aerobic physical activity on older patients with mild cognitive impairment. Changes in brain size and cognition are noted. Read & Research Alzheimer’s More

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Researchers have uncovered evidence that marijuana reduces blood flow in the brain, particularly in the hippocampus – the region affected by Alzheimer’s. Read & Research Alzheimer’s More

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A multidisciplinary research, conceived by Dr. Francesco Bifari, Department of Medical Biotechnology and Translational Medicine, University of Milan, Italy and Dr. Read & Research Alzheimer’s More

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The use of benzodiazepines and related drugs increases the risk of hip fracture by 43% in persons with Alzheimer’s disease, according to a new study from the University of Eastern Finland. Read & Research Alzheimer’s More

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Eli Lilly and Company has announced that their drug solanezumab has failed to meet its primary endpoint of slowing cognitive decline in people with mild Alzheimer’s disease. Read & Research Alzheimer’s More

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A recent study from the University of Eastern Finland shows that among users of antidementia drugs, persons using memantine have the highest risk of pneumonia. Read & Research Alzheimer’s More

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Study reveals new insights into the molecular mechanisms of beta-amyloid buildup – a hallmark of Alzheimer’s disease – in the retina of people with AMD. Read & Research Alzheimer’s More

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New research questions the benefits of occupational therapy for patients with Alzheimer’s disease, particularly for slowing down functional decline. Read & Research Alzheimer’s More

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Research from the University of Southampton gives new insight into possible causes of Age-related Macular Degeneration (AMD), a leading cause of vision loss among people aged 50 and older. Read & Research Alzheimer’s More

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Circadian alterations are prevalent in Alzheimer’s disease (AD) and may contribute to cognitive impairment, behavioral symptoms, and neurodegeneration. Epigenetic mechanisms regulate the circadian clock, and changes in DNA methylation have been reported in AD brains, but the pathways that mediate circadian deregulation in AD are incompletely understood. We hypothesized that Read & Research Alzheimer’s More

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Despite worries that dementia will escalate in the coming years, new research suggests the prevalence of the disorder may be decreasing. Read & Research Alzheimer’s More

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What is the diagnosis and outcome of dementia? Learn about treatment option changes over time and what living with dementia in later stages may be like. Read & Research Alzheimer’s More

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Whether co-occurring neuropathologies interact or independently affect clinical disease progression is uncertain. We estimated rates of clinical progression and tested whether associations between clinical progression and Alzheimer’s disease neuropathology (ADNP) were modified by co-occurring Lewy body disease (LBD) or vascular brain injury (VBI). Read & Research Alzheimer’s More

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Accurate diagnosis of prion diseases and discrimination from alternative dementias gain importance in the clinical routine, but partial overlap in cerebrospinal fluid (CSF) biomarkers impedes absolute discrimination in the differential diagnostic context. Read & Research Alzheimer’s More

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New research from the Djavad Mowafaghian Centre for Brain Health at UBC has found a way to partially restore brain cell communication around areas damaged by plaques associated with Alzheimer’s… Read & Research Alzheimer’s More

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Hypertension is a leading risk factor for dementia and other disorders associated with cognitive decline. Read & Research Alzheimer’s More

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New research finds patients who use anticoagulants – especially those with irregular heartbeat – may be at greater risk of developing dementia. Read & Research Alzheimer’s More

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Using four tests to assess older adults’ sense of smell, researchers were able to predict which individuals were at increased risk of Alzheimer’s disease. Read & Research Alzheimer’s More

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To help people live well with dementia we need a better understanding of its psychological impact, according to a new British Psychological Society report (BPS). Read & Research Alzheimer’s More

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Researchers found people with Alzheimer’s who consumed probiotics every day for 12 weeks showed improvements in cognitive functioning. Read & Research Alzheimer’s More

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Synapses, the place where brain cells contact one another, play a pivotal role in the transmission of toxic proteins. Read & Research Alzheimer’s More

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Study of memory function in early midlife period pinpoints changes linked with menopause. Read & Research Alzheimer’s More

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Complex and time-consuming memory clinic referral criteria are contributing to delays in the diagnosis of dementia, according to a paper published by the Journal of the Royal Society of Medicine. Read & Research Alzheimer’s More

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Women have better memories than men throughout life, even though their ability to recall dips at menopause. This study links memory function with hormones. Read & Research Alzheimer’s More

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Researchers at Tohoku University have found a promising treatment for Alzheimer’s disease, by noticing a similarity in the way insulin signaling works in the brain and in the pancreas of diabetic… Read & Research Alzheimer’s More

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Alzheimer’s disease is a neurodegenerative disorder for which, despite years of research, there are no effective treatments or cures. Read & Research Alzheimer’s More

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Subjective cognitive decline (SCD) manifesting before clinical impairment could serve as a target population for early intervention trials in Alzheimer’s disease (AD). A working group, the Subjective Cognitive Decline Initiative (SCD-I), published SCD research criteria in the context of preclinical AD. To successfully apply them, a number of issues regarding Read & Research Alzheimer’s More

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New compound that better identifies amyloid clumps could be used in PET scans to detect early brain changes and track treatment in Alzheimer’s disease. Read & Research Alzheimer’s More

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It’s tempting to dip into the leftover Halloween treats, but new research out of York University has found eating plenty of fruits and vegetables, combined with regular exercise, leads to better… Read & Research Alzheimer’s More

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