Biomarkers that identify individuals at risk of Alzheimer’s disease (AD) development would be highly valuable. Plasma concentration of amyloid β (Aβ)—central in the pathogenesis of AD—is a logical candidate, but studies to date have produced conflicting results on its utility. Read & Research Alzheimer’s More
DNA methylation is a key epigenetic mechanism in brain aging and Alzheimer’s disease (AD). The newly discovered 5-hydroxymethylcytosine mediates DNA demethylation, is highly abundant in the brain, and is dynamically regulated by life experiences. However, little is known about its genome-wide patterns and potential role in AD. Read & Research Alzheimer’s More
Variations in the structure of amyloid-beta peptide deposits that develop in the brain tissue of patients with Alzheimer’s disease are associated with different clinical subtypes of the disease, a… Read & Research Alzheimer’s More
There has been a strong link between human exposure to aluminium and the incidence of Alzheimer’s disease for half a century or more. Read & Research Alzheimer’s More
A large-scale study carried out by researchers in Canada suggests that living near major, busy roads may increase the risk of developing dementia. Read & Research Alzheimer’s More
Available data and models for the health-economic evaluation of treatment in Alzheimer’s disease (AD) have limitations causing uncertainty to decision makers. Forthcoming treatment strategies in preclinical or early AD warrant an update on the challenges associated with their economic evaluation. Read & Research Alzheimer’s More
A French observational study in real life showed that dementia patients benefiting from occupational therapy sessions report relevant clinical benefits over the intervention period, according to a… Read & Research Alzheimer’s More
A study of more than 2,000 Finnish men has uncovered a link between frequent sauna use and reduced risk of Alzheimer’s and other forms of dementia. Read & Research Alzheimer’s More
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