Archive for March, 2017

Hippocampal volume is a core biomarker of Alzheimer’s disease (AD). However, its contribution over the standard diagnostic workup is unclear. Read & Research Alzheimer’s More

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Excess sugar consumption has been linked with Alzheimer’s disease (AD) pathology in animal models. Read & Research Alzheimer’s More

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Spatial navigation deficits are reported in dementia, but their temporal relationship to cognitive decline is not established. Read & Research Alzheimer’s More

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We investigated the clinical differences between familial and sporadic frontotemporal dementia (FTD), screening for mutations in known FTD genes. Read & Research Alzheimer’s More

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We assessed the diagnostic accuracy of cerebrospinal fluid (CSF) YKL-40 in discriminating (1) clinical Alzheimer’s disease (AD) from cognitively healthy controls (HCs) and frontotemporal dementia (FTD) (level I) and (2) patients stratified by different pathophysiological profiles from HCs and FTD following a novel unbiased/descriptive categorization based on CSF biomarkers, independent Read & Research Alzheimer’s More

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Disclosing amyloid status to cognitively normal individuals remains controversial given our lack of understanding the test’s clinical significance and unknown psychological risk. Read & Research Alzheimer’s More

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A recent study investigating the interaction between two proteins may offer novel drug targets for neurodegenerative diseases such as Alzheimer’s. Read & Research Alzheimer’s More

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A new large-scale study in the United Kingdom finds a small but significant increased risk of dementia for individuals with an autoimmune disease. Read & Research Alzheimer’s More

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A classification framework for posterior cortical atrophy (PCA) is proposed to improve the uniformity of definition of the syndrome in a variety of research settings. Read & Research Alzheimer’s More

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