Archive for October, 2017

We sought to assess the individual and combined contribution of limbic and neocortical α-synuclein, tau, and β-amyloid to duration of illness in dementia with Lewy bodies (DLB). Read & Research Alzheimer’s More

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A new study in mice finds that amyloid beta from outside the brain can cause brain plaques, neuron damage, and other hallmarks of Alzheimer’s disease. Read & Research Alzheimer’s More

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Researchers are well aware that significant delays can occur after submitting their protocols to their institutional review boards (IRBs), whether hospital or university based, and whether their project is already funded or not. If the project is multisite and involving multiple IRBs, the delays can be exponential. Read & Research Alzheimer’s More

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Comparative transcriptome analyses in Alzheimer’s disease (AD) and other neurodegenerative proteinopathies can uncover both shared and distinct disease pathways. Read & Research Alzheimer’s More

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High-level improvement of diagnostic certainty and management is provided by selective and hierarchical implementation of florbetaben PET into current standard practices for the most complex dementia cases. Read & Research Alzheimer’s More

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Some people have Alzheimer’s-related brain pathologies but never go on to develop the disease. New research may have found the reason why. Read & Research Alzheimer’s More

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Cortical mean diffusivity (MD) and free water (FW) changes are proposed biomarkers for Alzheimer’s disease (AD). Read & Research Alzheimer’s More

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A new study suggests that anticoagulants – old and new – may have a protective effect against dementia in patients with atrial fibrillation. Read & Research Alzheimer’s More

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Researchers are hopeful that one day, Alzheimer’s disease could be prevented with a vaccine that has recently shown positive results in mice. Read & Research Alzheimer’s More

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Delayed word processing may predict the onset of Alzheimer’s disease, scientists find. The research may lead to new testing practices. Read & Research Alzheimer’s More

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The 2-year Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) multidomain lifestyle intervention trial (NCT01041989) demonstrated beneficial effects on cognition. We investigated whether sociodemographics, socioeconomic status, baseline cognition, or cardiovascular factors influenced intervention effects on cognition. Read & Research Alzheimer’s More

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It is unclear whether abnormalities in brain glucose homeostasis are associated with Alzheimer’s disease (AD) pathogenesis. Read & Research Alzheimer’s More

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Researchers reveal how a compound in green tea called EGCG prevents the formation of toxic beta-amyloid plaques, which are a hallmark of Alzheimer’s. Read & Research Alzheimer’s More

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A new study looked at the metabolic changes in the brains of menopausal and perimenopausal women and found potential triggers for Alzheimer’s disease. Read & Research Alzheimer’s More

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A new study looked at the metabolic changes in the brains of menopausal and perimenopausal women and found potential triggers for Alzheimer’s disease. Read & Research Alzheimer’s More

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Scientific evidence collected over the past four decades suggests that a loss of cholinergic innervation in the cerebral cortex of patients with Alzheimer’s disease (AD) is an early pathogenic event correlated with cognitive impairment. This evidence led to the formulation of the “cholinergic hypothesis of AD” and the development of Read & Research Alzheimer’s More

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Cognitive and/or memory impairment are the main clinical markers currently used to identify subjects at risk of developing dementia. This study aimed to explore the relationship between the presence of neuropsychiatric symptoms and dementia incidence. Read & Research Alzheimer’s More

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Researchers suggest that the loss of a gene called LSD1 plays a role in the brain cell death that occurs with Alzheimer’s and frontotemporal dementia. Read & Research Alzheimer’s More

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Women who develop high blood pressure in their 40s may be at greater risk of dementia, a new study finds, but this association may not ring true for men. Read & Research Alzheimer’s More

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With the number of bilingual individuals increasing steadily, find out how bilingualism affects the brain and cognitive function. Read & Research Alzheimer’s More

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