We sought to assess the individual and combined contribution of limbic and neocortical α-synuclein, tau, and β-amyloid to duration of illness in dementia with Lewy bodies (DLB). Read & Research Alzheimer’s More
Archive for October, 2017
The limbic and neocortical contribution of α-synuclein, tau, and β-amyloid to disease duration in dementia with Lewy bodies"> The limbic and neocortical contribution of α-synuclein, tau, and β-amyloid to disease duration in dementia with Lewy bodies
Posted October 31, 2017 ByAlzheimer's: Protein from outside the brain may be involved"> Alzheimer's: Protein from outside the brain may be involved
Posted October 31, 2017 ByA new study in mice finds that amyloid beta from outside the brain can cause brain plaques, neuron damage, and other hallmarks of Alzheimer’s disease. Read & Research Alzheimer’s More
Progress in transnational scientific and ethics review: Commentary on the proposal for a single North American review board for research on dementia"> Progress in transnational scientific and ethics review: Commentary on the proposal for a single North American review board for research on dementia
Posted October 28, 2017 ByResearchers are well aware that significant delays can occur after submitting their protocols to their institutional review boards (IRBs), whether hospital or university based, and whether their project is already funded or not. If the project is multisite and involving multiple IRBs, the delays can be exponential. Read & Research Alzheimer’s More
Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases"> Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases
Posted October 26, 2017 ByComparative transcriptome analyses in Alzheimer’s disease (AD) and other neurodegenerative proteinopathies can uncover both shared and distinct disease pathways. Read & Research Alzheimer’s More
Added value of 18F-florbetaben amyloid PET in the diagnostic workup of most complex patients with dementia in France: A naturalistic study"> Added value of 18F-florbetaben amyloid PET in the diagnostic workup of most complex patients with dementia in France: A naturalistic study
Posted October 26, 2017 ByHigh-level improvement of diagnostic certainty and management is provided by selective and hierarchical implementation of florbetaben PET into current standard practices for the most complex dementia cases. Read & Research Alzheimer’s More
Alzheimer's: Brain's protective mechanism revealed"> Alzheimer's: Brain's protective mechanism revealed
Posted October 26, 2017 BySome people have Alzheimer’s-related brain pathologies but never go on to develop the disease. New research may have found the reason why. Read & Research Alzheimer’s More
Cortical microstructural changes along the Alzheimer's disease continuum"> Cortical microstructural changes along the Alzheimer's disease continuum
Posted October 25, 2017 ByCortical mean diffusivity (MD) and free water (FW) changes are proposed biomarkers for Alzheimer’s disease (AD). Read & Research Alzheimer’s More
Blood thinners slash dementia risk in A-fib patients"> Blood thinners slash dementia risk in A-fib patients
Posted October 25, 2017 ByA new study suggests that anticoagulants – old and new – may have a protective effect against dementia in patients with atrial fibrillation. Read & Research Alzheimer’s More
Could Alzheimer's be prevented with a vaccine?"> Could Alzheimer's be prevented with a vaccine?
Posted October 24, 2017 ByResearchers are hopeful that one day, Alzheimer’s disease could be prevented with a vaccine that has recently shown positive results in mice. Read & Research Alzheimer’s More
Alzheimer's: Word processing duration may predict onset"> Alzheimer's: Word processing duration may predict onset
Posted October 20, 2017 ByDelayed word processing may predict the onset of Alzheimer’s disease, scientists find. The research may lead to new testing practices. Read & Research Alzheimer’s More
Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics: The FINGER trial"> Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics: The FINGER trial
Posted October 19, 2017 ByThe 2-year Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) multidomain lifestyle intervention trial (NCT01041989) demonstrated beneficial effects on cognition. We investigated whether sociodemographics, socioeconomic status, baseline cognition, or cardiovascular factors influenced intervention effects on cognition. Read & Research Alzheimer’s More
Evidence for brain glucose dysregulation in Alzheimer's disease"> Evidence for brain glucose dysregulation in Alzheimer's disease
Posted October 19, 2017 ByIt is unclear whether abnormalities in brain glucose homeostasis are associated with Alzheimer’s disease (AD) pathogenesis. Read & Research Alzheimer’s More
How a green tea compound could prevent Alzheimer's"> How a green tea compound could prevent Alzheimer's
Posted October 13, 2017 ByResearchers reveal how a compound in green tea called EGCG prevents the formation of toxic beta-amyloid plaques, which are a hallmark of Alzheimer’s. Read & Research Alzheimer’s More
Menopause may trigger Alzheimer's disease"> Menopause may trigger Alzheimer's disease
Posted October 11, 2017 ByA new study looked at the metabolic changes in the brains of menopausal and perimenopausal women and found potential triggers for Alzheimer’s disease. Read & Research Alzheimer’s More
Menopause may trigger Alzheimer's disease"> Menopause may trigger Alzheimer's disease
Posted October 11, 2017 ByA new study looked at the metabolic changes in the brains of menopausal and perimenopausal women and found potential triggers for Alzheimer’s disease. Read & Research Alzheimer’s More
Revisiting the cholinergic hypothesis in Alzheimer's disease: Emerging evidence from translational and clinical research"> Revisiting the cholinergic hypothesis in Alzheimer's disease: Emerging evidence from translational and clinical research
Posted October 10, 2017 ByScientific evidence collected over the past four decades suggests that a loss of cholinergic innervation in the cerebral cortex of patients with Alzheimer’s disease (AD) is an early pathogenic event correlated with cognitive impairment. This evidence led to the formulation of the “cholinergic hypothesis of AD” and the development of Read & Research Alzheimer’s More
Neuropsychiatric symptoms as risk factors of dementia in a Mexican population: A 10/66 Dementia Research Group study"> Neuropsychiatric symptoms as risk factors of dementia in a Mexican population: A 10/66 Dementia Research Group study
Posted October 10, 2017 ByCognitive and/or memory impairment are the main clinical markers currently used to identify subjects at risk of developing dementia. This study aimed to explore the relationship between the presence of neuropsychiatric symptoms and dementia incidence. Read & Research Alzheimer’s More
Dementia: Study helps to unravel the cause of brain cell death"> Dementia: Study helps to unravel the cause of brain cell death
Posted October 9, 2017 ByResearchers suggest that the loss of a gene called LSD1 plays a role in the brain cell death that occurs with Alzheimer’s and frontotemporal dementia. Read & Research Alzheimer’s More
Women's dementia risk increased by midlife hypertension"> Women's dementia risk increased by midlife hypertension
Posted October 5, 2017 ByWomen who develop high blood pressure in their 40s may be at greater risk of dementia, a new study finds, but this association may not ring true for men. Read & Research Alzheimer’s More
Bilingualism: What happens in the brain?"> Bilingualism: What happens in the brain?
Posted October 4, 2017 ByWith the number of bilingual individuals increasing steadily, find out how bilingualism affects the brain and cognitive function. Read & Research Alzheimer’s More