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Cerebral small vessel disease in middle age and genetic predisposition to late-onset Alzheimer's disease

Cerebral small vessel disease (CSVD) is associated with late-onset Alzheimer’s disease (LOAD) and might contribute to the relationship between apolipoprotein E ε4 (APOEε4) and LOAD, in older people. However, it is unclear whether CSVD begins in middle age in individuals genetically predisposed to LOAD. Read & Research Alzheimer’s More

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