Archive for December, 2017

Editorial Board"> Editorial Board

Posted December 29, 2017 By

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Investigators from 26 countries met in Varna, Bulgaria, October 19–20, 2017, at the second in a series of Alzheimer’s Association International Conference® satellite symposia. Researchers discussed new pathways in Alzheimer’s disease (AD) and dementia research, with a particular focus on new therapeutic opportunities. The goals of the meeting were three-fold: Read & Research Alzheimer’s More

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AF710B (aka ANAVEX 3-71) is a novel selective allosteric M1 muscarinic and sigma-1 receptor agonist. In 3×Tg-AD mice, AF710B attenuates cognitive deficits and decreases Alzheimer-like hallmarks. We now report on the long-lasting disease-modifying properties of AF710B in McGill-R-Thy1-APP transgenic (Tg) rats. Read & Research Alzheimer’s More

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Cognitive decline is a distressing experience, but there may be an easy way of keeping your brain healthy. Just take a moderately long walk every day. Read & Research Alzheimer’s More

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Genetic associations for endophenotypes of Alzheimer’s disease (AD) in cognitive stages preceding AD have not been thoroughly evaluated. Read & Research Alzheimer’s More

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Blueberry vinegar could benefit people with dementia, say researchers, after finding that the fermented product improved memory in mice with amnesia. Read & Research Alzheimer’s More

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A new study has suggested that uncoupling between slow waves and spindles in non-REM sleep may be the cause of overnight forgetting in older brains. Read & Research Alzheimer’s More

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The aim was to examine associations between midlife cardiovascular health (CVH) and 20-year cognitive decline among blacks and whites. Read & Research Alzheimer’s More

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Cross-sectional findings using the tau tracer [18F]THK5317 (THK5317) have shown that [18F]fluorodeoxyglucose (FDG) positron emission tomography data can be approximated using perfusion measures (early-frame standardized uptake value ratio; ratio of tracer delivery in target to reference regions). In this way, a single positron emission tomography study can provide both functional Read & Research Alzheimer’s More

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Ten benefits of shilajit"> Ten benefits of shilajit

Posted December 16, 2017 By

Shilajit, also called mineral pitch, is the result of a long process of breaking down plant matter and minerals. Learn about the potential health benefits. Read & Research Alzheimer’s More

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Exposure to traumatic brain injury is a core risk factor that predisposes an individual to sporadic neurodegenerative diseases. We provide evidence that mechanical stress increases brain levels of hallmark proteins associated with neurodegeneration. Read & Research Alzheimer’s More

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Neurodegenerative disorders have been a graveyard for hundreds of well-intentioned efforts at drug discovery and development. Concussion and other traumatic brain injuries (TBIs) and Alzheimer’s disease (AD) share many overlapping pathologies and possible clinical links. Read & Research Alzheimer’s More

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An animal model of late-onset Alzheimer’s disease is needed to research what causes degeneration in the absence of dominant genetic insults and why the association cortex is particularly vulnerable to degeneration. Read & Research Alzheimer’s More

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A diet supplemented with canola oil worsened memory and led to weight gain in mouse models of Alzheimer’s disease, researchers report. Read & Research Alzheimer’s More

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Researchers have shown that hyperbaric oxygen therapy alleviates some physical and behavioral symptoms of Alzheimer’s in a mouse model of the disease. Read & Research Alzheimer’s More

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We forecast the prevalence of preclinical and clinical Alzheimer’s disease (AD) and evaluated potential impacts of primary and secondary preventions in the United States. Read & Research Alzheimer’s More

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Scientists have designed a molecule that can interfere with the production of the APOE protein. Mouse tests reveal that the compound prevents brain damage. Read & Research Alzheimer’s More

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A global study of more than 1 million people reveals how obesity in midlife and being underweight near onset are both linked to raised risk of dementia. Read & Research Alzheimer’s More

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