Archive for April, 2018

Alzheimer’s disease can cause people living with it to experience severe anxiety as they try to navigate an unfamiliar world. Can music help them to cope? Read & Research Alzheimer’s More

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A new study links long-term anticholinergic use for depression, Parkinson’s, and loss of bladder control to raised risk of dementia up to 20 years later. Read & Research Alzheimer’s More

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Recognizing dementia in general hospitals allows for tailored care. We aimed to assess hospital dementia diagnosis accuracy, changes over time, and predictors of correct identification. Read & Research Alzheimer’s More

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The aim of this study was to investigate the association between acetylcholinesterase inhibitor (AChEI) use and risk of ischemic stroke and death in people with dementia. Read & Research Alzheimer’s More

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The first population study of sense of smell and cognitive performance by age suggests that testing sense of smell could be a marker for cognitive decline. Read & Research Alzheimer’s More

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Recognizing dementia in general hospitals allows for tailored care. We aimed to assess hospital dementia diagnosis accuracy, changes over time, and predictors of correct identification. Read & Research Alzheimer’s More

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We know that eating fish protects brain health. A new study identifies the protein responsible for this and explains how it fights ‘Parkinson’s protein.’ Read & Research Alzheimer’s More

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Posted April 21, 2018 By

Described by poet Carl Sandburg as the “City of Big Shoulders,” Chicago will host a big conference July 22-26: the Alzheimer’s Association International Conference® 2018 (AAIC®). AAIC is the world’s largest gathering of Alzheimer’s and dementia researchers, drawing more than 5,000 attendees from over 70 countries in 2017. Register now Read & Research Alzheimer’s More

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We investigated brain demyelination in aging, mild cognitive impairment (MCI), and dementia using magnetic resonance imaging of myelin. Read & Research Alzheimer’s More

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In June 2017, a diverse group of experts in Alzheimer’s disease convened to discuss how to accelerate getting new drugs to patients to both prevent and treat the disease. Participants concluded that we need a more robust, diversified drug development pipeline. Strategic policy measures can help keep new Alzheimer’s disease Read & Research Alzheimer’s More

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Changes in glucose levels may represent a powerful metabolic indicator of dementia in African-Americans with diabetes. It is unclear whether these changes also occur in Caucasians. Read & Research Alzheimer’s More

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Researchers have found that large, fibrous aggregates thought to drive Lou Gehrig’s disease might actually help to protect motor neurons. Read & Research Alzheimer’s More

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A new study shows that the brain’s immune cells retain a memory of previous inflammation, which causes them to react differently to toxic brain proteins. Read & Research Alzheimer’s More

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Posted April 13, 2018 By

In the March 2018 issue of Alzheimer’s & Dementia, the article “2018 Alzheimer’s Disease Facts and Figures” incorrectly reported the estimated total lifetime cost of care (including Medicare, Medicaid, out-of-pocket expenditures, and the value of informal care) per person with dementia. The correct cost is estimated at $341,840 in 2017 Read & Research Alzheimer’s More

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A study reveals that levels of a protein called beta-amyloid — which is associated with Alzheimer’s — increase after a single night of sleep deprivation. Read & Research Alzheimer’s More

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In a first-of-its kind study, scientists use human neurons to study and correct the damaging effects of the APOE4 gene, a well-known genetic risk factor. Read & Research Alzheimer’s More

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A new study in mice shows that manipulating a biological clock circuit alters patterns of aggressiveness that mimic those of humans with Alzheimer’s. Read & Research Alzheimer’s More

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Combining antibody technology and an infrared sensor, a groundbreaking test could make the early detection of Alzheimer’s disease a possibility. Read & Research Alzheimer’s More

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One characteristic of Alzheimer’s disease is the formation of amyloid-β plaques, which are typically linked to neuroinflammation and surrounded by inflammatory cells such as microglia and infiltrating immune cells. Here, we describe nonneurogenic doublecortin (DCX) positive cells, DCX being generally used as a marker for young immature neurons, at sites Read & Research Alzheimer’s More

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Coffee is often hailed for its health benefits, but new research finds that long-term consumption could be more of a hindrance for people with Alzheimer’s. Read & Research Alzheimer’s More

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We examined and compared plasma phospho-tau181 (pTau181) and total tau: (1) across the Alzheimer’s disease (AD) clinical spectrum; (2) in relation to brain amyloid β (Aβ) positron emission tomography (PET), tau PET, and cortical thickness; and (3) as a screening tool for elevated brain Aβ. Read & Research Alzheimer’s More

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Scientists find that a lack of dopamine in the brain may cause some of the earliest symptoms of Alzheimer’s disease, a condition with growing prevalence. Read & Research Alzheimer’s More

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Prospective, population-based studies can be rich resources for dementia research. Follow-up in many such studies is through linkage to routinely collected, coded health-care data sets. We evaluated the accuracy of these data sets for dementia case identification. Read & Research Alzheimer’s More

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