Archive for May, 2018

Following an analysis of existing studies, researchers conclude that there is a link between depression and age-related cognitive decline. Read & Research Alzheimer’s More

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There is one question often asked during scientific meetings, business travel, or dinner parties that is just as easily and equally posed by members of the research community, the general public, or by friends and family: what’s new in Alzheimer’s research? Today, there is growing interest from readers into the Read & Research Alzheimer’s More

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Our objective was to investigate the effect of sex on cognitive decline within the context of amyloid β (Aβ) burden and apolipoprotein E genotype. Read & Research Alzheimer’s More

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Young people should take better care of their hearing, new research warns, or they may expose themselves to a heightened risk of cognitive impairments. Read & Research Alzheimer’s More

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Lifetime risks are the probabilities of progressing to Alzheimer’s disease (AD) dementia during one’s lifespan. Here, we report the first estimates of the lifetime and ten-year risks of AD dementia based on age, gender, and biomarker tests for preclinical disease. Read & Research Alzheimer’s More

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Genome-wide association studies consistently show that single nucleotide polymorphisms (SNPs) in the complement receptor 1 (CR1) gene modestly but significantly alter Alzheimer’s disease (AD) risk. Follow-up research has assumed that CR1 is expressed in the human brain despite a paucity of evidence for its function there. Alternatively, erythrocytes contain >80% Read & Research Alzheimer’s More

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Both polymorphisms and mutations in glucocerebrosidase (GBA) may influence the development of dementia in patients with Parkinson’s disease. Read & Research Alzheimer’s More

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Although the apolipoprotein E ε4-allele (APOE-ε4) is a susceptibility factor for Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB), its relationship with imaging and cognitive measures across the AD/DLB spectrum remains unexplored. Read & Research Alzheimer’s More

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In March, a $414 million increase for Alzheimer’s disease (AD) and dementia research funding at the National Institutes of Health and Kevin and Avonte’s Law, important legislation to protect those who wander, were signed into law. Read & Research Alzheimer’s More

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A landmark study sheds light on the underlying mechanisms that impact neural health in Parkinson’s disease and dementia. Can it lead to better treatments? Read & Research Alzheimer’s More

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The interplay between midlife vascular risk factors and midlife cognitive function with later life mild cognitive impairment (MCI) and dementia (DEM) is not well understood. Read & Research Alzheimer’s More

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According to the latest study, cholesterol plays a role in the formation of plaques in Alzheimer’s disease. The findings open new avenues for drug design. Read & Research Alzheimer’s More

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Recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies and clinical trials limit the development of new treatments. Widespread Internet use allows data capture from participants in an unsupervised setting. The Brain Health Registry, a website and online registry, collects data from participants and their study partners. Read & Research Alzheimer’s More

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Using machine learning techniques, researchers reveal new dementia risks. They conclude that marital status, BMI, and sleep may all play a role. Read & Research Alzheimer’s More

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As we grow older, we find it harder to stay focused, perhaps due to changes in the brain’s attention hub. Could this also drive the onset of Alzheimer’s? Read & Research Alzheimer’s More

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We conducted Japanese Alzheimer’s Disease Neuroimaging Initiative (J-ADNI) and compared the basic characteristics and progression profiles with those of ADNI in North America. Read & Research Alzheimer’s More

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A study that followed more than 350,000 veterans found a raised risk of dementia in those who had had TBI — even mild TBI without loss of consciousness. Read & Research Alzheimer’s More

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Researchers have found a small molecule that can block the spread of the toxic protein tau, a hallmark of Alzheimer’s progression. Read & Research Alzheimer’s More

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Posted May 4, 2018 By

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Healthy physiological systems exhibit fractal regulation (FR), generating similar fluctuation patterns in physiological outputs across different time scales. FR in motor activity is degraded in dementia, and the degradation correlates to cognitive decline. We tested whether degraded FR predicts Alzheimer’s disease dementia. Read & Research Alzheimer’s More

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Posted May 3, 2018 By

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New research suggests that moderate to severe anxiety in midlife may be an independent risk factor for developing dementia in old age. Read & Research Alzheimer’s More

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