Archive for June, 2018

Infectious agents were recently implicated in Alzheimer’s disease (AD) and etiology of other dementias, notably Helicobacter pylori. Read & Research Alzheimer’s More

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Although Congress has allocated substantial funding to accelerate dementia research, nearly all attempts to find effective preventions and treatments for dementia have failed. Current dementia therapies offer little hope. They provide only modest clinical benefits and have limited impact on the unrelenting progression of disease. With few means to slow Read & Research Alzheimer’s More

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The body needs vitamin B-12 for many processes. People with a deficiency may have neurological symptoms and fatigue, while an excess may indicate liver disease or diabetes. Doctors can use a vitamin B-12 level test to determine how much B-12 is in the body. Find out more about the test Read & Research Alzheimer’s More

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Early-onset Alzheimer’s disease is a form of dementia that begins before the age of 65. Recognizing the initial symptoms can help a person seek treatment earlier and slow the progression of the disease. In this article, learn about ten signs of early-onset Alzheimer’s. We also cover how to help a Read & Research Alzheimer’s More

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Cerebrospinal fluid (CSF) biomarkers have the potential to improve the diagnostic accuracy of Alzheimer’s disease, yet there is a lack of harmonized preanalytical CSF handling protocols. Read & Research Alzheimer’s More

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Agitation is one of the most challenging neuropsychiatric symptoms to treat in Alzheimer’s disease and has significant implications for patient and caregiver. A major source of difficulty in identifying safe and effective treatments for agitation is the lack of validated biomarkers. As such, patients may not be appropriately targeted, and Read & Research Alzheimer’s More

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Cognitive function is an important end point of treatments in dementia clinical trials. Measuring cognitive function by standardized tests, however, is biased toward highly constrained environments (such as hospitals) in selected samples. Patient-powered real-world evidence using information and communication technology devices, including environmental and wearable sensors, may help to overcome Read & Research Alzheimer’s More

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Longitudinal studies are needed to understand the long-term associations between stroke and dementia. Read & Research Alzheimer’s More

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A study of large sets of postmortem data provides new evidence that viruses — herpes HHV-6 and HHV-7 in particular — may be involved in Alzheimer’s. Read & Research Alzheimer’s More

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Technology interventions are showing promise to assist persons with dementia and their carers. However, low adoption rates for these technologies and ethical considerations have impeded the realization of their full potential. Read & Research Alzheimer’s More

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Helicobacter pylori infection might increase risk of dementia, but available evidence is inconsistent, and longitudinal studies are sparse. We investigated the association between H. pylori serology and dementia risk in a population-based cohort. Read & Research Alzheimer’s More

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A study of brain CT scans of patients with memory problems found that diabetes and smoking were linked to hippocampal calcifications. Read & Research Alzheimer’s More

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Hypertension in middle age is known to increase the risk of dementia, but so far the specifics are unclear. A new study sheds fresh light on this matter. Read & Research Alzheimer’s More

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Precision medicine methodologies and approaches have advanced our understanding of the clinical presentation, development, progression, and management of Alzheimer’s disease (AD) dementia. However, sex and gender have not yet been adequately integrated into many of these approaches. Read & Research Alzheimer’s More

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Heavy drinking is a risk factor for the development of Alzheimer’s. New research now reveals how alcohol may endanger the brain by impairing its defenses. Read & Research Alzheimer’s More

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Memory naturally declines with age, but a new study shows that there may be an easy way to protect it — namely, by staying socially active. Read & Research Alzheimer’s More

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