Read Research Alzheimer's More http://fuckalzheimers.com/2018/07/04/n-methyl-d-aspartate-receptormediated-calcium-influx-connects-amyloid-oligomers-to-ectopic-neuronal-cell-cycle-reentry-in-alzheimers-disease/' title='Share this by email.' class='social email'>           

N-methyl-D-aspartate receptor–mediated calcium influx connects amyloid-β oligomers to ectopic neuronal cell cycle reentry in Alzheimer's disease

Alzheimer’s disease (AD) symptoms reflect synaptic dysfunction and neuron death. Amyloid-β oligomers (AβOs) induce excess calcium entry into neurons via N-methyl-D-aspartate receptors (NMDARs), contributing to synaptic dysfunction. The study described here tested the hypothesis that AβO-stimulated calcium entry also drives neuronal cell cycle reentry (CCR), a prelude to neuron death Read & Research Alzheimer’s More

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