Associations between the Mediterranean-DASH diet Intervention for Neurological Delay (MIND) diet and incidence of cognitive impairment have not been evaluated outside the United States. Read & Research Alzheimer’s More
Archive for February, 2019
MIND not Mediterranean diet related to 12-year incidence of cognitive impairment in an Australian longitudinal cohort study"> MIND not Mediterranean diet related to 12-year incidence of cognitive impairment in an Australian longitudinal cohort study
Posted February 27, 2019 ByALS: New technique prevents toxic protein deposits in cells"> ALS: New technique prevents toxic protein deposits in cells
Posted February 27, 2019 ByClumps of faulty TDP-43 protein inside nerve cells are common in ALS and other neurological diseases. Could this new technique offer a way to prevent them? Read & Research Alzheimer’s More
Alteration in sleep architecture and electroencephalogram as an early sign of Alzheimer's disease preceding the disease pathology and cognitive decline"> Alteration in sleep architecture and electroencephalogram as an early sign of Alzheimer's disease preceding the disease pathology and cognitive decline
Posted February 25, 2019 ByThe present work aims to evaluate the significance of sleep disturbance and electroencephalogram (EEG) alteration in the early stage of Alzheimer’s disease (AD). Read & Research Alzheimer’s More
Alzheimer's: 'Holy herb' extract shows promise as future treatment"> Alzheimer's: 'Holy herb' extract shows promise as future treatment
Posted February 22, 2019 ByA laboratory screen found that a compound in the Yerba santa medicinal plant protects against several age-related triggers of death in mouse nerve cells. Read & Research Alzheimer’s More
How language shapes our brains...and our lives"> How language shapes our brains...and our lives
Posted February 22, 2019 ByIn this Spotlight, we look at the origins of spoken language, where language is present in the brain, and how the languages we speak shape our world. Read & Research Alzheimer’s More
The unexpected dangers of gum disease"> The unexpected dangers of gum disease
Posted February 22, 2019 ByAccording to recent research, gum disease may increase the risk of a range of seemingly unrelated conditions, including cancer and dementia. Read & Research Alzheimer’s More
What are the early signs of dementia?"> What are the early signs of dementia?
Posted February 21, 2019 ByThere are 10 early signs and symptoms of dementia, including misplacing things, difficulty solving problems, and confusing times and places. Learn about the other signs in this article. Read & Research Alzheimer’s More
Incidence of dementia after age 90 in a multiracial cohort"> Incidence of dementia after age 90 in a multiracial cohort
Posted February 20, 2019 ByLittle is known about dementia incidence in diverse populations of oldest-old, the age group with highest dementia incidence. Read & Research Alzheimer’s More
Ethnoracial differences in Alzheimer's disease from the FLorida Autopsied Multi-Ethnic (FLAME) cohort"> Ethnoracial differences in Alzheimer's disease from the FLorida Autopsied Multi-Ethnic (FLAME) cohort
Posted February 18, 2019 ByOur primary goal was to examine demographic and clinicopathologic differences across an ethnoracially diverse autopsy-confirmed cohort of Alzheimer’s disease cases. Read & Research Alzheimer’s More
Diabetes and Alzheimer's: What's the link?"> Diabetes and Alzheimer's: What's the link?
Posted February 17, 2019 ByAlthough scientists have linked Alzheimer’s and diabetes, the exact connection has been difficult to unpick. A recent study now gives further insight. Read & Research Alzheimer’s More
Hospitalization, surgery, and incident dementia"> Hospitalization, surgery, and incident dementia
Posted February 15, 2019 ByWe evaluated whether hospitalization with or without surgery increases risk for dementia or Alzheimer’s disease. Read & Research Alzheimer’s More
Study finds new cognitive decline mechanism in Alzheimer's"> Study finds new cognitive decline mechanism in Alzheimer's
Posted February 15, 2019 ByA new animal study has identified the cellular mechanism that leads to reduced blood flow to the brain, which, in turn, impacts cognitive function. Read & Research Alzheimer’s More
Inflammation in midlife hastens cognitive decline"> Inflammation in midlife hastens cognitive decline
Posted February 15, 2019 ByUnderstanding the risk factors of cognitive decline are now more important than ever. A recent study examined the potential role of inflammation. Read & Research Alzheimer’s More
Staging biomarkers in preclinical autosomal dominant Alzheimer's disease by estimated years to symptom onset"> Staging biomarkers in preclinical autosomal dominant Alzheimer's disease by estimated years to symptom onset
Posted February 14, 2019 ByStaging preclinical Alzheimer disease (AD) by the expected years to symptom onset (EYO) in autosomal dominant AD (ADAD) through biomarker correlations is important. Read & Research Alzheimer’s More
GeneMatch: A novel recruitment registry using at-home APOE genotyping to enhance referrals to Alzheimer's prevention studies"> GeneMatch: A novel recruitment registry using at-home APOE genotyping to enhance referrals to Alzheimer's prevention studies
Posted February 13, 2019 ByRecruitment for Alzheimer’s disease (AD) prevention research studies is challenging because of lack of awareness among cognitively healthy adults coupled with the high screen fail rate due to participants not having a genetic risk factor or biomarker evidence of the disease. Participant recruitment registries offer one solution for efficiently and Read & Research Alzheimer’s More
Alzheimer's: How do tau tangles grow?"> Alzheimer's: How do tau tangles grow?
Posted February 12, 2019 ByResearchers use a mathematical model and lab experiments to unravel the process through which tangles of the protein tau grow in length. Read & Research Alzheimer’s More
Clinical and cortical decline in the aphasic variant of Alzheimer's disease"> Clinical and cortical decline in the aphasic variant of Alzheimer's disease
Posted February 11, 2019 ByPrimary progressive aphasia (PPA) displays variable progression trajectories that require further elucidation. Read & Research Alzheimer’s More
Genetic origin of a large family with a novel PSEN1 mutation (Ile416Thr)"> Genetic origin of a large family with a novel PSEN1 mutation (Ile416Thr)
Posted February 8, 2019 ByA small percentage of Alzheimer’s disease (AD) cases are caused by genetic mutations with autosomal dominant inheritance. We report a family with a novel variant in PSEN1. Read & Research Alzheimer’s More
Blood-clotting protein contributes to Alzheimer's"> Blood-clotting protein contributes to Alzheimer's
Posted February 7, 2019 ByThough experts typically name beta-amyloid plaques as the main culprits in Alzheimer’s disease, new research finds another factor: a leaked blood protein. Read & Research Alzheimer’s More
Does education really protect against dementia?"> Does education really protect against dementia?
Posted February 7, 2019 ByDoes the length of time an individual spends in education reduce the risk of developing dementia? A new, large-scale study investigates. Read & Research Alzheimer’s More
Erratum to “Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies” [Alzheimer’s & Dementia 2018;14:707-22.]"> Erratum to “Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies” [Alzheimer’s & Dementia 2018;14:707-22.]
Posted February 5, 2019 ByIn the article “Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies,” published in the June 2018 issue of Alzheimer’s & Dementia, the lower bounds of the confidence intervals are noted twice in Table 4. The corrected table is below. Read & Research Alzheimer’s More
Early versus late MCI: Improved MCI staging using a neuropsychological approach"> Early versus late MCI: Improved MCI staging using a neuropsychological approach
Posted February 5, 2019 ByThe Alzheimer’s Disease Neuroimaging Initiative (ADNI) separates “early” and “late” mild cognitive impairment (MCI) based on a single memory test. We compared ADNI’s MCI classifications to our neuropsychological approach, which more broadly assesses cognitive abilities. Read & Research Alzheimer’s More
Dementia: Could gut bacteria play a role?"> Dementia: Could gut bacteria play a role?
Posted February 1, 2019 ByA new study links changes in gut bacteria to dementia. The researchers hope that their findings might, one day, help develop more effective treatment. Read & Research Alzheimer’s More