Archive for February, 2019

Our primary goal was to examine demographic and clinicopathologic differences across an ethnoracially diverse autopsy-confirmed cohort of Alzheimer’s disease cases. Read & Research Alzheimer’s More

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Although scientists have linked Alzheimer’s and diabetes, the exact connection has been difficult to unpick. A recent study now gives further insight. Read & Research Alzheimer’s More

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We evaluated whether hospitalization with or without surgery increases risk for dementia or Alzheimer’s disease. Read & Research Alzheimer’s More

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A new animal study has identified the cellular mechanism that leads to reduced blood flow to the brain, which, in turn, impacts cognitive function. Read & Research Alzheimer’s More

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Understanding the risk factors of cognitive decline are now more important than ever. A recent study examined the potential role of inflammation. Read & Research Alzheimer’s More

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Staging preclinical Alzheimer disease (AD) by the expected years to symptom onset (EYO) in autosomal dominant AD (ADAD) through biomarker correlations is important. Read & Research Alzheimer’s More

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Recruitment for Alzheimer’s disease (AD) prevention research studies is challenging because of lack of awareness among cognitively healthy adults coupled with the high screen fail rate due to participants not having a genetic risk factor or biomarker evidence of the disease. Participant recruitment registries offer one solution for efficiently and Read & Research Alzheimer’s More

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Researchers use a mathematical model and lab experiments to unravel the process through which tangles of the protein tau grow in length. Read & Research Alzheimer’s More

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Primary progressive aphasia (PPA) displays variable progression trajectories that require further elucidation. Read & Research Alzheimer’s More

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A small percentage of Alzheimer’s disease (AD) cases are caused by genetic mutations with autosomal dominant inheritance. We report a family with a novel variant in PSEN1. Read & Research Alzheimer’s More

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Though experts typically name beta-amyloid plaques as the main culprits in Alzheimer’s disease, new research finds another factor: a leaked blood protein. Read & Research Alzheimer’s More

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Does the length of time an individual spends in education reduce the risk of developing dementia? A new, large-scale study investigates. Read & Research Alzheimer’s More

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In the article “Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies,” published in the June 2018 issue of Alzheimer’s & Dementia, the lower bounds of the confidence intervals are noted twice in Table 4. The corrected table is below. Read & Research Alzheimer’s More

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The Alzheimer’s Disease Neuroimaging Initiative (ADNI) separates “early” and “late” mild cognitive impairment (MCI) based on a single memory test. We compared ADNI’s MCI classifications to our neuropsychological approach, which more broadly assesses cognitive abilities. Read & Research Alzheimer’s More

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A new study links changes in gut bacteria to dementia. The researchers hope that their findings might, one day, help develop more effective treatment. Read & Research Alzheimer’s More

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