Archive for February, 2019

Associations between the Mediterranean-DASH diet Intervention for Neurological Delay (MIND) diet and incidence of cognitive impairment have not been evaluated outside the United States. Read & Research Alzheimer’s More

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Clumps of faulty TDP-43 protein inside nerve cells are common in ALS and other neurological diseases. Could this new technique offer a way to prevent them? Read & Research Alzheimer’s More

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The present work aims to evaluate the significance of sleep disturbance and electroencephalogram (EEG) alteration in the early stage of Alzheimer’s disease (AD). Read & Research Alzheimer’s More

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A laboratory screen found that a compound in the Yerba santa medicinal plant protects against several age-related triggers of death in mouse nerve cells. Read & Research Alzheimer’s More

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In this Spotlight, we look at the origins of spoken language, where language is present in the brain, and how the languages we speak shape our world. Read & Research Alzheimer’s More

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According to recent research, gum disease may increase the risk of a range of seemingly unrelated conditions, including cancer and dementia. Read & Research Alzheimer’s More

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There are 10 early signs and symptoms of dementia, including misplacing things, difficulty solving problems, and confusing times and places. Learn about the other signs in this article. Read & Research Alzheimer’s More

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Little is known about dementia incidence in diverse populations of oldest-old, the age group with highest dementia incidence. Read & Research Alzheimer’s More

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Our primary goal was to examine demographic and clinicopathologic differences across an ethnoracially diverse autopsy-confirmed cohort of Alzheimer’s disease cases. Read & Research Alzheimer’s More

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Although scientists have linked Alzheimer’s and diabetes, the exact connection has been difficult to unpick. A recent study now gives further insight. Read & Research Alzheimer’s More

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We evaluated whether hospitalization with or without surgery increases risk for dementia or Alzheimer’s disease. Read & Research Alzheimer’s More

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A new animal study has identified the cellular mechanism that leads to reduced blood flow to the brain, which, in turn, impacts cognitive function. Read & Research Alzheimer’s More

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Understanding the risk factors of cognitive decline are now more important than ever. A recent study examined the potential role of inflammation. Read & Research Alzheimer’s More

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Staging preclinical Alzheimer disease (AD) by the expected years to symptom onset (EYO) in autosomal dominant AD (ADAD) through biomarker correlations is important. Read & Research Alzheimer’s More

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Recruitment for Alzheimer’s disease (AD) prevention research studies is challenging because of lack of awareness among cognitively healthy adults coupled with the high screen fail rate due to participants not having a genetic risk factor or biomarker evidence of the disease. Participant recruitment registries offer one solution for efficiently and Read & Research Alzheimer’s More

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Researchers use a mathematical model and lab experiments to unravel the process through which tangles of the protein tau grow in length. Read & Research Alzheimer’s More

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Primary progressive aphasia (PPA) displays variable progression trajectories that require further elucidation. Read & Research Alzheimer’s More

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A small percentage of Alzheimer’s disease (AD) cases are caused by genetic mutations with autosomal dominant inheritance. We report a family with a novel variant in PSEN1. Read & Research Alzheimer’s More

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Though experts typically name beta-amyloid plaques as the main culprits in Alzheimer’s disease, new research finds another factor: a leaked blood protein. Read & Research Alzheimer’s More

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Does the length of time an individual spends in education reduce the risk of developing dementia? A new, large-scale study investigates. Read & Research Alzheimer’s More

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In the article “Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies,” published in the June 2018 issue of Alzheimer’s & Dementia, the lower bounds of the confidence intervals are noted twice in Table 4. The corrected table is below. Read & Research Alzheimer’s More

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The Alzheimer’s Disease Neuroimaging Initiative (ADNI) separates “early” and “late” mild cognitive impairment (MCI) based on a single memory test. We compared ADNI’s MCI classifications to our neuropsychological approach, which more broadly assesses cognitive abilities. Read & Research Alzheimer’s More

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A new study links changes in gut bacteria to dementia. The researchers hope that their findings might, one day, help develop more effective treatment. Read & Research Alzheimer’s More

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