Alzheimer's disease: Brain immune cells may offer new treatment target

Recent Research

• Brain imaging measurements of fibrillar amyloid-β burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE ε4 allele December 9, 2019
• Alzheimer’s risk gene and heavy metal exposure may impair cognition December 6, 2019
• Repairing leaky blood-brain barrier may rejuvenate brain function December 6, 2019
• What to know about CoQ10 and its dosage December 5, 2019
• Real-world evidence in Alzheimer’s disease: The ROADMAP Data Cube November 28, 2019
• Neuropsychological decline up to 20 years before incident mild cognitive impairment November 28, 2019
• Incidence of dementia in the oldest-old and its relationship with age: The Monzino 80-plus population-based study November 27, 2019
• Association between alcohol consumption and Alzheimer’s disease: A Mendelian randomization study November 27, 2019
• Extra virgin olive oil may protect against various dementias November 27, 2019
• Tau-positron emission tomography correlates with neuropathology findings November 26, 2019
• Incidence of frontotemporal disorders in Olmsted County: A population-based study November 26, 2019
• Alzheimer’s: Poor air quality may contribute to cognitive decline November 22, 2019
• Inflammation drives tau damage in Alzheimer’s November 22, 2019
• Apolipoprotein E genotype and the association between C-reactive protein and postoperative delirium: Importance of gene-protein interactions November 21, 2019
• Clinical meaningfulness of subtle cognitive decline on longitudinal testing in preclinical AD November 20, 2019
• A research framework for cognitive aging and Alzheimer’s disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos—Investigation of Neurocognitive Aging (SOL-INCA) November 20, 2019
• Study finds no link between statin use and memory harm in older adults November 19, 2019
• Prevalence and correlates of mild cognitive impairment among diverse Hispanics/Latinos: Study of Latinos-Investigation of Neurocognitive Aging results November 18, 2019
• Illiteracy may triple dementia risk November 14, 2019
• Retinal imaging shows promise in early detection of Alzheimer’s November 13, 2019
• Why is my leg shaking? November 13, 2019
• Scientists propose new theory of Parkinson’s disease November 12, 2019
• Does childhood cognition predict dementia risk later in life? November 10, 2019
• Leisure activity and social integration mitigate the risk of dementia related to cardiometabolic diseases: A population-based longitudinal study November 9, 2019
• The path forward in Alzheimer’s disease therapeutics: Reevaluating the amyloid cascade hypothesis November 6, 2019
• Does waist size predict dementia risk? November 5, 2019
• How waste gets ‘washed out’ of our brains during sleep November 2, 2019
• Individualized clinical management of patients at risk for Alzheimer’s dementia October 30, 2019
• C99 selectively accumulates in vulnerable neurons in Alzheimer’s disease October 30, 2019
• Intact global cognitive and olfactory ability predicts lack of transition to dementia October 29, 2019
• Secular trends in cognitive trajectories of diverse older adults October 28, 2019
• Distinct tau PET patterns in atrophy-defined subtypes of Alzheimer’s disease October 28, 2019
• Dementia risk higher in those who eat more trans fats October 28, 2019
• How a high salt diet may lead to cognitive decline October 25, 2019
• Synaptic, axonal damage and inflammatory cerebrospinal fluid biomarkers in neurodegenerative dementias October 24, 2019
• Amyloid pathology–produced unexpected modifications of calcium homeostasis in hippocampal subicular dendrites October 24, 2019
• What is apraxia? October 24, 2019
• Failed dementia drug gets a second chance October 24, 2019
• New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures October 23, 2019
• Automated sensor-based detection of challenging behaviors in advanced stages of dementia in nursing homes October 23, 2019
• Targeting the ensemble of heterogeneous tau oligomers in cells: A novel small molecule screening platform for tauopathies October 22, 2019
• Heart and brain health are connected, but what influences both? October 22, 2019
• The longitudinal evaluation of familial frontotemporal dementia subjects protocol: Framework and methodology October 18, 2019
• Multicenter Alzheimer’s and Parkinson’s disease immune biomarker verification study October 17, 2019
• Dementia: Brain mapping method may predict progression October 16, 2019
• MCI: Should memory tests score males and females differently? October 16, 2019
• Longitudinal study of self-reported hearing loss and subjective cognitive function decline in women October 15, 2019
• Predicting incident dementia 3-8 years after brief cognitive tests in the UK Biobank prospective study of 500,000 people October 13, 2019
• Alzheimer’s disease: Brain immune cells may offer new treatment target October 11, 2019
• What to know about acetylcholine October 11, 2019
• Sleep and neurocognitive decline in the Hispanic Community Health Study/Study of Latinos October 9, 2019
• Local ancestry at APOE modifies Alzheimer’s disease risk in Caribbean Hispanics October 9, 2019
• Existing blood thinner delays Alzheimer’s disease in mice October 8, 2019
• Association between enrollment factors and incident cognitive impairment in Blacks and Whites: Data from the Alzheimer’s Disease Center October 7, 2019
• Escitalopram for agitation in Alzheimer’s disease (S-CitAD): Methods and design of an investigator-initiated, randomized, controlled, multicenter clinical trial October 6, 2019
• Assessment of the appropriate use criteria for amyloid PET in an unselected memory clinic cohort: The ABIDE project October 6, 2019
• Declining incidence of dementia: A national registry-based study over 20 years October 3, 2019
• Current and past leisure time physical activity in relation to risk of Alzheimer’s disease in older adults October 3, 2019
• 95% of people think they could develop dementia with age September 30, 2019
• Alcohol and dementia risk: A complex relationship September 28, 2019
• Perspective: Clinical relevance of the dichotomous classification of Alzheimer’s disease biomarkers: Should there be a “gray zone”? September 26, 2019
• New approach may save brain cells in neurodegenerative diseases September 26, 2019
• Fluctuating blood pressure may speed up cognitive decline in Alzheimer’s September 25, 2019
• Differences in service utilization at an urban tribal health organization before and after Alzheimer’s disease or related dementia diagnosis: A cohort study September 25, 2019
• Walking patterns may help differentiate types of dementia September 24, 2019
• Apolipoprotein E ε4 allele effects on longitudinal cognitive trajectories are sex and age dependent September 24, 2019
• Multidomain intervention and/or omega-3 in nondemented elderly subjects according to amyloid status September 23, 2019
• Alzheimer’s: Head device reduces memory loss in 7 out of 8 people September 20, 2019
• Do Alzheimer’s and Lewy body disease have discrete pathological signatures of gait? September 20, 2019
• Can exercise slow down Alzheimer’s? September 19, 2019
• How to care for someone with Alzheimer’s disease September 18, 2019
• Hearing aids lower the chance of dementia, depression, and falling September 15, 2019
• Migraine may raise dementia, Alzheimer’s risk September 10, 2019
• The Alzheimer’s Disease Exposome September 10, 2019
• Quantitative gait, cognitive decline, and incident dementia: The Rotterdam Study September 9, 2019