Alzheimer's disease: Brain immune cells may offer new treatment target

Recent Research

• Could some antibiotics help treat early onset dementia? January 14, 2020
• What to know about brain atrophy January 8, 2020
• Could hydration levels influence cognitive function? January 5, 2020
• Scientists draw closer to a dementia vaccine January 4, 2020
• What causes Alzheimer’s? Not toxic amyloid, new study suggests January 4, 2020
• Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer’s disease December 23, 2019
• Effects of a combined transcranial magnetic stimulation (TMS) and cognitive training intervention in patients with Alzheimer’s disease December 23, 2019
• Dementia: Obesity, but not diet or inactivity, raises risk December 22, 2019
• Inflammatory marker could be early warning for dementia December 21, 2019
• Stratifying risk for dementia onset using large-scale electronic health record data: a retrospective cohort study December 17, 2019
• How two experimental Alzheimer’s drugs reverse aging December 13, 2019
• Mouse study tests a novel approach against Alzheimer’s December 12, 2019
• Transport breakdown in brain cells may lead to Alzheimer’s, Parkinson’s December 11, 2019
• Brain imaging measurements of fibrillar amyloid-β burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE ε4 allele December 9, 2019
• Alzheimer’s risk gene and heavy metal exposure may impair cognition December 6, 2019
• Repairing leaky blood-brain barrier may rejuvenate brain function December 6, 2019
• What to know about CoQ10 and its dosage December 5, 2019
• Real-world evidence in Alzheimer’s disease: The ROADMAP Data Cube November 28, 2019
• Neuropsychological decline up to 20 years before incident mild cognitive impairment November 28, 2019
• Incidence of dementia in the oldest-old and its relationship with age: The Monzino 80-plus population-based study November 27, 2019
• Association between alcohol consumption and Alzheimer’s disease: A Mendelian randomization study November 27, 2019
• Extra virgin olive oil may protect against various dementias November 27, 2019
• Tau-positron emission tomography correlates with neuropathology findings November 26, 2019
• Incidence of frontotemporal disorders in Olmsted County: A population-based study November 26, 2019
• Alzheimer’s: Poor air quality may contribute to cognitive decline November 22, 2019
• Inflammation drives tau damage in Alzheimer’s November 22, 2019
• Apolipoprotein E genotype and the association between C-reactive protein and postoperative delirium: Importance of gene-protein interactions November 21, 2019
• Clinical meaningfulness of subtle cognitive decline on longitudinal testing in preclinical AD November 20, 2019
• A research framework for cognitive aging and Alzheimer’s disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos—Investigation of Neurocognitive Aging (SOL-INCA) November 20, 2019
• Study finds no link between statin use and memory harm in older adults November 19, 2019
• Prevalence and correlates of mild cognitive impairment among diverse Hispanics/Latinos: Study of Latinos-Investigation of Neurocognitive Aging results November 18, 2019
• Illiteracy may triple dementia risk November 14, 2019
• Retinal imaging shows promise in early detection of Alzheimer’s November 13, 2019
• Why is my leg shaking? November 13, 2019
• Scientists propose new theory of Parkinson’s disease November 12, 2019
• Does childhood cognition predict dementia risk later in life? November 10, 2019
• Leisure activity and social integration mitigate the risk of dementia related to cardiometabolic diseases: A population-based longitudinal study November 9, 2019
• The path forward in Alzheimer’s disease therapeutics: Reevaluating the amyloid cascade hypothesis November 6, 2019
• Does waist size predict dementia risk? November 5, 2019
• How waste gets ‘washed out’ of our brains during sleep November 2, 2019
• Individualized clinical management of patients at risk for Alzheimer’s dementia October 30, 2019
• C99 selectively accumulates in vulnerable neurons in Alzheimer’s disease October 30, 2019
• Intact global cognitive and olfactory ability predicts lack of transition to dementia October 29, 2019
• Secular trends in cognitive trajectories of diverse older adults October 28, 2019
• Distinct tau PET patterns in atrophy-defined subtypes of Alzheimer’s disease October 28, 2019
• Dementia risk higher in those who eat more trans fats October 28, 2019
• How a high salt diet may lead to cognitive decline October 25, 2019
• Synaptic, axonal damage and inflammatory cerebrospinal fluid biomarkers in neurodegenerative dementias October 24, 2019
• Amyloid pathology–produced unexpected modifications of calcium homeostasis in hippocampal subicular dendrites October 24, 2019
• What is apraxia? October 24, 2019
• Failed dementia drug gets a second chance October 24, 2019
• New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures October 23, 2019
• Automated sensor-based detection of challenging behaviors in advanced stages of dementia in nursing homes October 23, 2019
• Targeting the ensemble of heterogeneous tau oligomers in cells: A novel small molecule screening platform for tauopathies October 22, 2019
• Heart and brain health are connected, but what influences both? October 22, 2019
• The longitudinal evaluation of familial frontotemporal dementia subjects protocol: Framework and methodology October 18, 2019
• Multicenter Alzheimer’s and Parkinson’s disease immune biomarker verification study October 17, 2019
• Dementia: Brain mapping method may predict progression October 16, 2019
• MCI: Should memory tests score males and females differently? October 16, 2019
• Longitudinal study of self-reported hearing loss and subjective cognitive function decline in women October 15, 2019
• Predicting incident dementia 3-8 years after brief cognitive tests in the UK Biobank prospective study of 500,000 people October 13, 2019
• Alzheimer’s disease: Brain immune cells may offer new treatment target October 11, 2019
• What to know about acetylcholine October 11, 2019
• Sleep and neurocognitive decline in the Hispanic Community Health Study/Study of Latinos October 9, 2019
• Local ancestry at APOE modifies Alzheimer’s disease risk in Caribbean Hispanics October 9, 2019
• Existing blood thinner delays Alzheimer’s disease in mice October 8, 2019
• Association between enrollment factors and incident cognitive impairment in Blacks and Whites: Data from the Alzheimer’s Disease Center October 7, 2019
• Escitalopram for agitation in Alzheimer’s disease (S-CitAD): Methods and design of an investigator-initiated, randomized, controlled, multicenter clinical trial October 6, 2019
• Assessment of the appropriate use criteria for amyloid PET in an unselected memory clinic cohort: The ABIDE project October 6, 2019
• Declining incidence of dementia: A national registry-based study over 20 years October 3, 2019
• Current and past leisure time physical activity in relation to risk of Alzheimer’s disease in older adults October 3, 2019
• 95% of people think they could develop dementia with age September 30, 2019
• Alcohol and dementia risk: A complex relationship September 28, 2019
• Perspective: Clinical relevance of the dichotomous classification of Alzheimer’s disease biomarkers: Should there be a “gray zone”? September 26, 2019
• New approach may save brain cells in neurodegenerative diseases September 26, 2019