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Amyloid pathology–produced unexpected modifications of calcium homeostasis in hippocampal subicular dendrites

Alzheimer’s disease (AD) is linked to neuronal calcium dyshomeostasis, which is associated with network hyperexcitability. Decreased expression of the calcium-binding protein calbindin-D28K (CB) might be a susceptibility factor for AD. The subiculum is affected early in AD, for unknown reasons. Read & Research Alzheimer’s More

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