Archive for December, 2019

We investigated plasma proteomic markers of astrocytopathy, brain degeneration, plasticity, and inflammation in sporadic early-onset versus late-onset Alzheimer’s disease (EOAD and LOAD). Read & Research Alzheimer’s More

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This clinical trial evaluates the efficacy and safety of a 6-week course of daily neuroAD™ therapy. Read & Research Alzheimer’s More

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New research suggests that it may only be obesity, not a poor diet or lack of physical activity, that contributes to dementia risk. Read & Research Alzheimer’s More

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New research identifies an inflammatory biomarker in the blood, called sCD14, that may predict someone’s risk of developing clinical dementia. Read & Research Alzheimer’s More

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Preventing dementia, or modifying disease course, requires identification of presymptomatic or minimally symptomatic high-risk individuals. Read & Research Alzheimer’s More

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New research in mice reveals the molecular and genetic mechanisms through which two Alzheimer’s drug candidates can reverse aging in general. Read & Research Alzheimer’s More

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In a mouse study, researchers have tested the potential of a ketone ester-rich diet in slowing down Alzheimer’s, and have found this approach promising. Read & Research Alzheimer’s More

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New research in mice and flies suggests that failure to transport molecules that break down proteins in neurons may lead to neurodegenerative diseases. Read & Research Alzheimer’s More

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We previously characterized associations between brain imaging measurements of amyloid-β (Aβ) plaque burden and apolipoprotein E (APOE) ϵ4 gene dose in a small number of cognitively unimpaired late-middle-aged APOE ϵ4 homozygotes (HMs), heterozygotes (HTs), and noncarriers (NCs). We now characterize cross-sectional Aβ plaque, tau tangle, and cortical atrophy (neurodegeneration) measurements, Read & Research Alzheimer’s More

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New research in mice suggests that exposure to cadmium can lead to cognitive decline in those with the Alzheimer’s risk gene APOE4. Read & Research Alzheimer’s More

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New research in mice suggests that a leaky blood-brain barrier can accelerate brain aging, and that targeting inflammation can reverse some changes. Read & Research Alzheimer’s More

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CoQ10 is a natural chemical that carries out a many vital roles in the body. Some people may take supplements to correct a CoQ10 deficiency. Read & Research Alzheimer’s More

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