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A drug used to reduce seizures has been found to normalize brain wave frequencies in patients with Alzheimer’s. Could this drug help to slow the disease? Read & Research Alzheimer’s More

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Going for a walk outside, reading, listening to music — these and other enjoyable activities can reduce blood pressure for elderly caregivers of spouses with Alzheimer’s disease, suggests a study in… Read & Research Alzheimer’s More

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NIH-funded tool may improve clinical trial design and aid in treatment development. Read & Research Alzheimer’s More

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A plant extract used for centuries in traditional medicine in Nigeria could form the basis of a new drug to treat Alzheimer’s disease, researchers at The University of Nottingham have found. Read & Research Alzheimer’s More

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Researchers at the University of Cambridge have designed antibodies that target the protein deposits in the brain associated with Alzheimer’s disease, and stop their production. Read & Research Alzheimer’s More

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A new study investigates the effect of extra-virgin olive oil on cognitive decline and brain inflammation in people with Alzheimer’s disease. Read & Research Alzheimer’s More

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The study investigated the role of neuropathologies in the relationship between TOMM40 ‘523 genotype and late-life cognitive decline. Read & Research Alzheimer’s More

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In one of the largest studies to date to use metabolomics, the study of compounds that are created through various chemical reactions in the body, researchers have been able to identify new… Read & Research Alzheimer’s More

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Obese mice with a particular version of a gene strongly associated with Alzheimer’s disease (AD) in humans show increased Alzheimer’s pathology, according to new research published in eNeuro. Read & Research Alzheimer’s More

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The mechanism triggering degeneration in Alzheimer’s disease (AD) remains uncertain. Therapeutic failure following β amyloid (Aβ) removal casts doubt on amyloid neurotoxicity per se as the primary cause of AD. Impaired microvascular function has been suggested as an alternative etiology. People with Down syndrome (DS) develop Alzheimer pathology, but whether Read & Research Alzheimer’s More

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Diabetes is prospectively associated with cognitive decline. Whether lower cognitive function and worse brain structure are prospectively associated with incident diabetes is unclear. Read & Research Alzheimer’s More

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Post-traumatic stress disorder (PTSD) is associated with an increased risk of dementia in male veterans, but little is known in females and civilians. Read & Research Alzheimer’s More

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With a rapidly aging population, general practitioners are confronting the challenge of how to determine those who are at greatest risk for dementia and potentially need more specialized follow-up to mitigate symptoms early in its course. We created a practical dementia risk score and provided individualized estimates of future dementia Read & Research Alzheimer’s More

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The identification of novel biomarkers associated with Alzheimer’s disease (AD) could provide key biological insights and permit targeted preclinical prevention. We investigated circulating metabolites associated with incident dementia and AD using metabolomics. Read & Research Alzheimer’s More

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Many previous studies have been limited by self- or proxy-reported injury or short follow-up. We investigated whether head or brain injuries are associated with Alzheimer’s disease (AD), possible modifying factors and dose-response relationship. Read & Research Alzheimer’s More

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Researchers at UC San Francisco have found that older people with persistent pain show quicker declines in memory as they age and are more likely to have dementia years later, an indication that… Read & Research Alzheimer’s More

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Functional and cognitive features of subjective cognitive decline (SCD) were identified in a longitudinal database from the National Alzheimer Coordinating Center. Read & Research Alzheimer’s More

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Long before symptoms of Alzheimer’s disease become apparent to patients and their families, biological changes are occurring within the brain. Read & Research Alzheimer’s More

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An international research team led by UvA researchers Jeroen Bos, Martin Vinck and Cyriel Pennartz has identified a new type of neuron which might play a vital role in humans’ ability to navigate… Read & Research Alzheimer’s More

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In North Africa and the Middle East, studies about dementia prevalence are scarce. The Arabic-validated 10/66 Dementia Research Group diagnostic assessment was used to assess the prevalence of dementia in Lebanon in a population-based study. The study also examined care arrangement and access to care. Read & Research Alzheimer’s More

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Research linking the metabolic gene TOMM40 with Alzheimer’s risk has produced mixed results for years. Now, a new study says family history is the reason. Read & Research Alzheimer’s More

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Neuroimaging shows increased blood flow in regions of the brain associated with memory and learning for people with higher omega-3 levels, according to a new report in the Journal of Alzheimer’s… Read & Research Alzheimer’s More

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Family history (FH) of Alzheimer’s disease (AD) affects mitochondrial function and may modulate effects of translocase of the outer mitochondrial membrane 40 kDa (TOMM40) rs10524523 (‘523) poly-T length on memory decline. Read & Research Alzheimer’s More

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Your spit may hold a clue to future brain health. Investigators at the Beaumont Research Institute, part of Beaumont Health in Michigan, are hopeful that their study involving small molecules in… Read & Research Alzheimer’s More

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Tau proteins are involved in more than twenty neurodegenerative diseases, including various forms of dementia. Read & Research Alzheimer’s More

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We examined the association between cognitive ability in young adulthood and dementia in Danish men, brothers, and male twins. Read & Research Alzheimer’s More

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The Mediterranean and Dietary Approaches to Stop Hypertension diets have been associated with lower dementia risk. We evaluated dietary inflammatory potential in relation to mild cognitive impairment (MCI)/dementia risk. Read & Research Alzheimer’s More

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Tau-mediated toxicity in Alzheimer’s disease is thought to operate through low-n oligomers, rather than filamentous aggregates. However, the nature of oligomers and pathways of toxicity are poorly understood. Therefore, we investigated structural and functional aspects of highly purified oligomers of a pro-aggregant tau species. Read & Research Alzheimer’s More

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New research led by the University of Hertfordshire, may significantly change the understanding of cognitive processes that are most impaired at very early stages of Alzheimer’s disease. Read & Research Alzheimer’s More

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Hypovitaminosis D has been associated with several chronic conditions; yet, its association with cognitive decline and the risk of dementia and Alzheimer’s disease (AD) has been inconsistent. Read & Research Alzheimer’s More

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