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Alzheimer's could be diagnosed early with sniff tests">Alzheimer's could be diagnosed early with sniff tests

A damaged sense of smell correlates with other biomarkers of Alzheimer’s disease, providing hope that smell tests might help diagnose the disease earlier. Read & Research Alzheimer’s More

New Machine Learning program shows promise for early Alzheimer's diagnosis">New Machine Learning program shows promise for early Alzheimer's diagnosis

A new machine learning program developed by researchers at Case Western Reserve University appears to outperform other methods for diagnosing Alzheimer’s disease before symptoms begin to interfere… Read & Research Alzheimer’s More

Alzheimer's: Low serotonin levels may drive development">Alzheimer's: Low serotonin levels may drive development

A new study examines serotonin transporters and suggests that rather than being an effect of Alzheimer’s disease, low serotonin may cause the illness. Read & Research Alzheimer’s More

Early life physical activity may prevent cognitive decline">Early life physical activity may prevent cognitive decline

A new study in rodents shows how physical exercise in early life creates a cognitive reserve that improves cognition and neuronal activity in later years. Read & Research Alzheimer’s More

Reaction time variation may be a marker that predicts mortality in old age">Reaction time variation may be a marker that predicts mortality in old age

A common indicator of neurobiological disturbance among the elderly may also be associated with mortality, according to a study published in the open access journal PLOS ONE by Nicole A. Read & Research Alzheimer’s More

A personalized approach to Alzheimer's disease prevention">A personalized approach to Alzheimer's disease prevention

Alzheimer’s disease (AD) is a type of dementia that causes problems with memory, thinking, and behavior. It affects more than 5 million Americans. Read & Research Alzheimer’s More

Making an older brain younger by manipulating a single gene">Making an older brain younger by manipulating a single gene

Researchers have restored brain plasticity in the visual cortex of middle-aged mice to that of a younger state by manipulating a gene called Arc. Read & Research Alzheimer’s More

Antidepressant use increases risk of head injuries among persons with Alzheimer's disease">Antidepressant use increases risk of head injuries among persons with Alzheimer's disease

Antidepressant use is associated with an increased risk of head injuries and traumatic brain injuries among persons with Alzheimer’s disease, according to a new study from the University of Eastern… Read & Research Alzheimer’s More

Alzheimer's disease: Targeting enzyme may reverse memory loss">Alzheimer's disease: Targeting enzyme may reverse memory loss

Researchers discover how to block the enzyme HDAC2 to reverse memory loss in mouse models of Alzheimer’s without disrupting other functions of the enzyme. Read & Research Alzheimer’s More

Scientists prevent neurodegeneration-associated protein clumping in lab study">Scientists prevent neurodegeneration-associated protein clumping in lab study

Scientists report in a new study that by imitating a natural process of cells, they prevented the formation of protein clumps associated with amyotrophic lateral sclerosis (ALS) and frontotemporal… Read & Research Alzheimer’s More

Scientists reveal role for lysosome transport in Alzheimer's disease progression">Scientists reveal role for lysosome transport in Alzheimer's disease progression

Researchers from Yale University School of Medicine have discovered that defects in the transport of lysosomes within neurons promote the buildup of protein aggregates in the brains of mice with… Read & Research Alzheimer’s More

Brain activity higher in women than men, study finds">Brain activity higher in women than men, study finds

A new study finds that women have higher activity in more regions of the brain than men, a discovery that may explain sex differences in brain disorders. Read & Research Alzheimer’s More

Life-extending protein could treat Alzheimer's and Parkinson's">Life-extending protein could treat Alzheimer's and Parkinson's

A new study successfully used the protein hormone klotho to improve cognition in mice with Parkinson’s and Alzheimer’s-like brain toxicity. Read & Research Alzheimer’s More

Action video games decrease gray matter, study finds">Action video games decrease gray matter, study finds

Action video games lead to a reduced volume of gray matter in the hippocampus, which can seriously impact brain health, a new study suggests. Read & Research Alzheimer’s More

Fluctuations in home-monitored blood pressure may raise dementia risk">Fluctuations in home-monitored blood pressure may raise dementia risk

Whether or not you have high blood pressure, your risk of dementia may be higher if your pressure varies a lot from day to day, according to new research in the American Heart Association’s journal… Read & Research Alzheimer’s More

Heart-healthy middle age tied to lower risk of dementia">Heart-healthy middle age tied to lower risk of dementia

Study finds that modifiable vascular risk factors such as diabetes, high blood pressure, and smoking in mid-life are tied to higher risk of dementia later. Read & Research Alzheimer’s More

Alzheimer's gene plays role in childhood IQ">Alzheimer's gene plays role in childhood IQ

Gene variation linked to Alzheimer’s is also associated with fluid intelligence in children, prompting questions about its role in cognitive functioning. Read & Research Alzheimer’s More

How can PTSD trigger Alzheimer's disease? Study sheds light">How can PTSD trigger Alzheimer's disease? Study sheds light

A new study finds a molecular link between early life post-traumatic stress disorder and the risk of Alzheimer’s disease in old age. Read & Research Alzheimer’s More

Your brain on autopilot: Alzheimer's disease patients have a larger caudate nucleus">Your brain on autopilot: Alzheimer's disease patients have a larger caudate nucleus

Patients with Alzheimer’s disease (AD) have a larger caudate nucleus, a brain area involved in habits and used to navigate in the environment on an autopilot mode, shows for the first time a… Read & Research Alzheimer’s More

Hospital patients with dementia and other causes of confusion have worse outcomes">Hospital patients with dementia and other causes of confusion have worse outcomes

Hospital patients with dementia and other causes of confusion have longer stays and worse treatment outcomes than people without the condition, research led by the University of Stirling has found. Read & Research Alzheimer’s More

Dementia: New substance improves brain function">Dementia: New substance improves brain function

The protein amyloid beta is believed to be the major cause of Alzheimer’s disease. Read & Research Alzheimer’s More

Plasma apolipoprotein E levels and risk of dementia—A Mendelian randomization study of 106,562 individuals">Plasma apolipoprotein E levels and risk of dementia—A Mendelian randomization study of 106,562 individuals

In recent prospective studies, low plasma levels of apolipoprotein E (apoE) are associated with high risk of dementia. Whether this reflects a causal association remains to be established. Read & Research Alzheimer’s More

Is it Alzheimer's disease or another dementia?">Is it Alzheimer's disease or another dementia?

New, noninvasive method may help with diagnosis.A new method may help determine whether a person has Alzheimer’s disease or frontotemporal dementia, two different types of dementia that often… Read & Research Alzheimer’s More

Peripheral complement interactions with amyloid β peptide in Alzheimer's disease: 2. Relationship to Aβ immunotherapy">Peripheral complement interactions with amyloid β peptide in Alzheimer's disease: 2. Relationship to Aβ immunotherapy

Our previous studies have shown that amyloid β peptide (Aβ) is subject to complement-mediated clearance from the peripheral circulation, and that this mechanism is deficient in Alzheimer’s disease. The mechanism should be enhanced by Aβ antibodies that form immune complexes (ICs) with Aβ, and therefore may be relevant to current Read & Research Alzheimer’s More

How physical exercise prevents dementia">How physical exercise prevents dementia

Numerous studies have shown that physical exercise seems beneficial in the prevention of cognitive impairment and dementia in old age. Read & Research Alzheimer’s More

Alzheimer's: New brain cell loss mechanism uncovered">Alzheimer's: New brain cell loss mechanism uncovered

The discovery could ‘spur a new area of Alzheimer’s disease research,’ say the scientists, who found a new pathway of neuronal loss in the condition. Read & Research Alzheimer’s More

Sleep characteristics and risk of dementia and Alzheimer's disease: The Atherosclerosis Risk in Communities Study">Sleep characteristics and risk of dementia and Alzheimer's disease: The Atherosclerosis Risk in Communities Study

This study tested the hypotheses that late-midlife obstructive sleep apnea (OSA) and short and long sleep duration are associated with dementia for more than 15 years of follow-up. Read & Research Alzheimer’s More

Steering an enzyme's 'scissors' shows potential for stopping Alzheimer's disease">Steering an enzyme's 'scissors' shows potential for stopping Alzheimer's disease

The old real estate adage about “location, location, location” might also apply to the biochemical genesis of Alzheimer’s disease, according to new research from the University of British Columbia. Read & Research Alzheimer’s More