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Alzheimer's: Head device reduces memory loss in 7 out of 8 people">Alzheimer's: Head device reduces memory loss in 7 out of 8 people

A clinical trial has found that an innovative electromagnetic therapy device significantly reduced memory loss in seven out of the eight participants. Read & Research Alzheimer’s More

Do Alzheimer's and Lewy body disease have discrete pathological signatures of gait?">Do Alzheimer's and Lewy body disease have discrete pathological signatures of gait?

We aimed to refine the hypothesis that dementia has a unique signature of gait impairment reflective of underlying pathology by considering two dementia subtypes, Alzheimer’s disease (AD) and Lewy body disease (LBD), and exploring the role of cognition in disease-specific gait impairments. Read & Research Alzheimer’s More

Can exercise slow down Alzheimer's?">Can exercise slow down Alzheimer's?

A new proof-of-concept study finds that people with Alzheimer’s biomarkers in the brain who exercise frequently experience slower deterioration. Read & Research Alzheimer’s More

How to care for someone with Alzheimer's disease">How to care for someone with Alzheimer's disease

Caring for someone with Alzheimer’s disease can be both challenging and rewarding. Learn about tips to make it easier, as well as when to seek professional help. Read & Research Alzheimer’s More

Hearing aids lower the chance of dementia, depression, and falling">Hearing aids lower the chance of dementia, depression, and falling

A recent study concludes that wearing hearing aids is associated with later onset of dementia and a reduced risk of anxiety, depression, and falls. Read & Research Alzheimer’s More

Migraine may raise dementia, Alzheimer's risk">Migraine may raise dementia, Alzheimer's risk

New research finds a ‘significant’ association between a history of migraine and various forms of dementia, and Alzheimer’s disease in particular. Read & Research Alzheimer’s More

The Alzheimer's Disease Exposome">The Alzheimer's Disease Exposome

Environmental factors are poorly understood in the etiology of Alzheimer’s disease (AD) and related dementias. The importance of environmental factors in gene environment interactions (GxE) is suggested by wide individual differences in cognitive loss, even for carriers of AD-risk genetic variants. Read & Research Alzheimer’s More

Quantitative gait, cognitive decline, and incident dementia: The Rotterdam Study">Quantitative gait, cognitive decline, and incident dementia: The Rotterdam Study

Poor gait has recently emerged as a potential prodromal feature of cognitive decline and dementia. We assessed to what extent various aspects of poor gait are independently associated with cognitive decline and incident dementia. Read & Research Alzheimer’s More

Genetic resilience to Alzheimer's disease in APOE ε4 homozygotes: A systematic review">Genetic resilience to Alzheimer's disease in APOE ε4 homozygotes: A systematic review

Individuals with homozygosity for the apolipoprotein E (APOE) ε4 allele are in the highest risk category for late-onset Alzheimer’s disease (LOAD). However, some individuals in this category do not develop LOAD beyond the age of 75 years, despite being at elevated genetic risk. These “resilient” individuals may carry protective genetic factors. Read & Research Alzheimer’s More

What to know about raspberry ketones">What to know about raspberry ketones

Raspberry ketones are the compounds that give raspberries their smell. Some people believe that they provide health benefits. Learn about the possible uses and side effects of raspberry ketones here. Read & Research Alzheimer’s More

In vivo measures of tau burden are associated with atrophy in early Braak stage medial temporal lobe regions in amyloid-negative individuals">In vivo measures of tau burden are associated with atrophy in early Braak stage medial temporal lobe regions in amyloid-negative individuals

It is unclear the degree to which tau pathology in the medial temporal lobe (MTL) measured by 18F-flortaucipir positron emission tomography relates to MTL subregional atrophy and whether this relationship differs between amyloid-β–positive and amyloid-β–negative individuals. Read & Research Alzheimer’s More

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay">Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

Plasma proteins have been widely studied as candidate biomarkers to predict brain amyloid deposition to increase recruitment efficiency in secondary prevention clinical trials for Alzheimer’s disease. Most such biomarker studies are targeted to specific proteins or are biased toward high abundant proteins. Read & Research Alzheimer’s More

MCI-to-normal reversion using neuropsychological criteria in the Alzheimer's Disease Neuroimaging Initiative">MCI-to-normal reversion using neuropsychological criteria in the Alzheimer's Disease Neuroimaging Initiative

The low mild cognitive impairment (MCI) to cognitively normal (CN) reversion rate in the Alzheimer’s Disease Neuroimaging Initiative (2-3%) suggests the need to examine reversion by other means. We applied comprehensive neuropsychological criteria (NP criteria) to determine the resulting MCI to CN reversion rate. Read & Research Alzheimer’s More

What side effects can fish oil cause?">What side effects can fish oil cause?

Fish oil supplements contain healthful omega-3 fatty acids. These dietary fats are available in fresh fish, as well, but too many may lead to unwanted or even dangerous side effects. Read & Research Alzheimer’s More

Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium">Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium

Behavior/Comportment/Personality (BEHAV) and Language (LANG) domains were added to the Clinical Dementia Rating (CDR®) for improving evaluation of patients with frontotemporal lobar degeneration (FTLD) (CDR® plus NACC FTLD). Read & Research Alzheimer’s More

Eye tracking tests may predict Alzheimer's risk">Eye tracking tests may predict Alzheimer's risk

Eye tracking tests help to distinguish between two subtypes of mild cognitive impairment and their respective risks of becoming Alzheimer’s. Read & Research Alzheimer’s More

Mild cognitive impairment: Meditation can boost brain health">Mild cognitive impairment: Meditation can boost brain health

New research suggests that mindfulness meditation can help boost brain health and improve cognitive reserve in older adults with mild cognitive impairment. Read & Research Alzheimer’s More

Reply to “Down Syndrome Cognitive Marker's Significance in Alzheimer's Disease and Dementia Management”">Reply to “Down Syndrome Cognitive Marker's Significance in Alzheimer's Disease and Dementia Management”

We thank Dr. Mahla for his interest in our work and for highlighting some of the important details of our analysis. While the high risk of developing Alzheimer’s disease (AD) in those with Down syndrome (DS) is well known [1], resulting in DS being the most common genetic cause of Read & Research Alzheimer’s More

Could targeting variants of this gene help fight Alzheimer's disease?">Could targeting variants of this gene help fight Alzheimer's disease?

Researchers have found variants of a gene that influence Alzheimer’s disease risk through their effect on a cerebrospinal fluid protein. Read & Research Alzheimer’s More

'Spontaneous chemistry' may drive Alzheimer's">'Spontaneous chemistry' may drive Alzheimer's

A new study asks whether subtle changes to the chemistry of proteins might explain why they build up in the brains of people with Alzheimer’s. Read & Research Alzheimer’s More

Dementia risk: The role of 'blood pressure patterns'">Dementia risk: The role of 'blood pressure patterns'

A new study investigates the importance of fluctuations in blood pressure from mid-age to later life. It asks how these changes relate to dementia risk. Read & Research Alzheimer’s More

Alzheimer's in women: Could midlife stress play a role?">Alzheimer's in women: Could midlife stress play a role?

New research suggests that experiencing a stressful life event may detrimentally impact older women’s memories and put them at risk of Alzheimer’s disease. Read & Research Alzheimer’s More

Alzheimer's: Death of key brain cells causes daytime sleepiness">Alzheimer's: Death of key brain cells causes daytime sleepiness

According to a new study, the buildup of toxic tau protein in key areas of the brain leads to major brain cell loss and daytime sleepiness in Alzheimer’s. Read & Research Alzheimer’s More

Mild cognitive impairment has similar alterations as Alzheimer's disease in gut microbiota">Mild cognitive impairment has similar alterations as Alzheimer's disease in gut microbiota

Gut microbiota changes before the onset of Alzheimer’s disease (AD) and the alterations could be detected in the stage of mild cognitive impairment (MCI). The findings might offer diagnostic biomarkers before the onset of dementia. Read & Research Alzheimer’s More

How to improve your memory: 8 techniques to try">How to improve your memory: 8 techniques to try

Brain function and memory naturally decline slightly as a person ages, but there are many techniques people can use to improve memory and prevent its loss. Learn about them here. Read & Research Alzheimer’s More

Social activity in your 60s may lower dementia risk by 12%">Social activity in your 60s may lower dementia risk by 12%

One of the most reliable studies of its kind has tracked participants over a 28-year period and found that greater social activity can lower dementia risk. Read & Research Alzheimer’s More

Neuropsychological latent classes at enrollment and postmortem neuropathology">Neuropsychological latent classes at enrollment and postmortem neuropathology

We classified individuals based on their baseline performance on cognitive measures and investigated the association between cognitive classifications and neuropathological findings ∼7 years later, as an external validator. Read & Research Alzheimer’s More