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Ethnoracial differences in Alzheimer's disease from the FLorida Autopsied Multi-Ethnic (FLAME) cohort">Ethnoracial differences in Alzheimer's disease from the FLorida Autopsied Multi-Ethnic (FLAME) cohort

Our primary goal was to examine demographic and clinicopathologic differences across an ethnoracially diverse autopsy-confirmed cohort of Alzheimer’s disease cases. Read & Research Alzheimer’s More

Diabetes and Alzheimer's: What's the link?">Diabetes and Alzheimer's: What's the link?

Although scientists have linked Alzheimer’s and diabetes, the exact connection has been difficult to unpick. A recent study now gives further insight. Read & Research Alzheimer’s More

Hospitalization, surgery, and incident dementia">Hospitalization, surgery, and incident dementia

We evaluated whether hospitalization with or without surgery increases risk for dementia or Alzheimer’s disease. Read & Research Alzheimer’s More

Study finds new cognitive decline mechanism in Alzheimer's">Study finds new cognitive decline mechanism in Alzheimer's

A new animal study has identified the cellular mechanism that leads to reduced blood flow to the brain, which, in turn, impacts cognitive function. Read & Research Alzheimer’s More

Inflammation in midlife hastens cognitive decline">Inflammation in midlife hastens cognitive decline

Understanding the risk factors of cognitive decline are now more important than ever. A recent study examined the potential role of inflammation. Read & Research Alzheimer’s More

Staging biomarkers in preclinical autosomal dominant Alzheimer's disease by estimated years to symptom onset">Staging biomarkers in preclinical autosomal dominant Alzheimer's disease by estimated years to symptom onset

Staging preclinical Alzheimer disease (AD) by the expected years to symptom onset (EYO) in autosomal dominant AD (ADAD) through biomarker correlations is important. Read & Research Alzheimer’s More

GeneMatch: A novel recruitment registry using at-home APOE genotyping to enhance referrals to Alzheimer's prevention studies">GeneMatch: A novel recruitment registry using at-home APOE genotyping to enhance referrals to Alzheimer's prevention studies

Recruitment for Alzheimer’s disease (AD) prevention research studies is challenging because of lack of awareness among cognitively healthy adults coupled with the high screen fail rate due to participants not having a genetic risk factor or biomarker evidence of the disease. Participant recruitment registries offer one solution for efficiently and Read & Research Alzheimer’s More

Alzheimer's: How do tau tangles grow?">Alzheimer's: How do tau tangles grow?

Researchers use a mathematical model and lab experiments to unravel the process through which tangles of the protein tau grow in length. Read & Research Alzheimer’s More

Genetic origin of a large family with a novel PSEN1 mutation (Ile416Thr)">Genetic origin of a large family with a novel PSEN1 mutation (Ile416Thr)

A small percentage of Alzheimer’s disease (AD) cases are caused by genetic mutations with autosomal dominant inheritance. We report a family with a novel variant in PSEN1. Read & Research Alzheimer’s More

Blood-clotting protein contributes to Alzheimer's">Blood-clotting protein contributes to Alzheimer's

Though experts typically name beta-amyloid plaques as the main culprits in Alzheimer’s disease, new research finds another factor: a leaked blood protein. Read & Research Alzheimer’s More

Does education really protect against dementia?">Does education really protect against dementia?

Does the length of time an individual spends in education reduce the risk of developing dementia? A new, large-scale study investigates. Read & Research Alzheimer’s More

Erratum to “Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies” [Alzheimer’s & Dementia 2018;14:707-22.]">Erratum to “Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies” [Alzheimer’s & Dementia 2018;14:707-22.]

In the article “Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies,” published in the June 2018 issue of Alzheimer’s & Dementia, the lower bounds of the confidence intervals are noted twice in Table 4. The corrected table is below. Read & Research Alzheimer’s More

Early versus late MCI: Improved MCI staging using a neuropsychological approach">Early versus late MCI: Improved MCI staging using a neuropsychological approach

The Alzheimer’s Disease Neuroimaging Initiative (ADNI) separates “early” and “late” mild cognitive impairment (MCI) based on a single memory test. We compared ADNI’s MCI classifications to our neuropsychological approach, which more broadly assesses cognitive abilities. Read & Research Alzheimer’s More

Dementia: Could gut bacteria play a role?">Dementia: Could gut bacteria play a role?

A new study links changes in gut bacteria to dementia. The researchers hope that their findings might, one day, help develop more effective treatment. Read & Research Alzheimer’s More

Alzheimer's disease and glaucoma: Look-alike neurodegenerative diseases">Alzheimer's disease and glaucoma: Look-alike neurodegenerative diseases

We read with great interest the article by Lee et al. [1] entitled “Associations between recent and established ophthalmic conditions and risk of Alzheimer’s disease” published recently in Alzheimer’s & Dementia. We are grateful to the authors for sharing their valuable data with the scientific community, and we appreciate their efforts Read & Research Alzheimer’s More

Dementia: The worrying 'rise of pseudomedicine'">Dementia: The worrying 'rise of pseudomedicine'

In a recent article, a team of neurologists attacks an ongoing increase in pseudomedicine that claims to protect brain health and treat dementia. Read & Research Alzheimer’s More

Hearing loss and cognitive decline: Study probes link">Hearing loss and cognitive decline: Study probes link

Data from an 8-year study of 10,000 men aged 62 or older reveals a link between hearing loss and a markedly greater risk of subjective cognitive decline. Read & Research Alzheimer’s More

Longitudinal study of hearing loss and subjective cognitive function decline in men">Longitudinal study of hearing loss and subjective cognitive function decline in men

We examined the relation between self-reported hearing loss, hearing aid use, and risk of subjective cognitive function (SCF) decline. Read & Research Alzheimer’s More

Mild cognitive impairment: Reducing blood pressure can lower risk">Mild cognitive impairment: Reducing blood pressure can lower risk

Controlling systolic blood pressure to below 120 mm Hg significantly lowered the risk of mild cognitive impairment in older adults. Read & Research Alzheimer’s More

How gum disease could lead to Alzheimer's">How gum disease could lead to Alzheimer's

Researchers find that an oral bacterium usually linked to gum disease also plays a role in Alzheimer’s. This finding has led to a new therapeutic approach. Read & Research Alzheimer’s More

Even low-level activity may help reduce dementia risk">Even low-level activity may help reduce dementia risk

According to a recent study, older adults who move around more are likely to have significantly better memory and thinking skills. Read & Research Alzheimer’s More

Alzheimer's: Could targeting this mechanism reverse memory decline?">Alzheimer's: Could targeting this mechanism reverse memory decline?

New study identifies gene expression changes behind memory loss and shows how targeting them reverses the loss temporarily in a mouse model of Alzheimer’s. Read & Research Alzheimer’s More

Alzheimer's blood test detects brain damage years before symptoms">Alzheimer's blood test detects brain damage years before symptoms

Testing blood levels of a protein that brain cells leak when faulty or dying detected people with Alzheimer’s disease years before their symptoms emerged. Read & Research Alzheimer’s More

Stool transplants from 'super donors' could be a cure-all">Stool transplants from 'super donors' could be a cure-all

New research suggests that fecal transplants from “super donors” could cure a host of conditions, ranging from irritable bowel syndrome to Alzheimer’s. Read & Research Alzheimer’s More

Alzheimer's: What leads to brain cell damage?">Alzheimer's: What leads to brain cell damage?

The toxic beta-amyloid protein inactivates a protein that is key to the functioning of the parts of brain cells that receive signals from other cells. Read & Research Alzheimer’s More

Leaky blood vessels may trigger Alzheimer's">Leaky blood vessels may trigger Alzheimer's

According to a recent study, leaky capillaries could be more important to the development of Alzheimer’s disease than protein buildup in the brain. Read & Research Alzheimer’s More

Stress may raise the risk of Alzheimer's disease">Stress may raise the risk of Alzheimer's disease

A Danish population-based study finds a strong link between psychological distress and the risk of developing Alzheimer’s disease. Read & Research Alzheimer’s More

Experimental drug may prevent Alzheimer's disease">Experimental drug may prevent Alzheimer's disease

A drug that researchers are testing against a range of conditions might also prevent Alzheimer’s. The drug blocks toxic protein buildup in the brain. Read & Research Alzheimer’s More

A lack of deep sleep could indicate Alzheimer's development">A lack of deep sleep could indicate Alzheimer's development

Sleep is vital to many aspects of well-being. A new study finds that older adults who are not getting enough quality sleep may be developing Alzheimer’s. Read & Research Alzheimer’s More