Tag Archive


#FuckAlzheimers alzheimers alzheimers search engine collective cure data database dementia directory disease facebook feed find a cure Fuck Alzheimers g8 mission news research rss search search engine. team twitter website

Genes vs. lifestyle: Study 'undermines fatalistic view of dementia'">Genes vs. lifestyle: Study 'undermines fatalistic view of dementia'

New research suggests that making healthful lifestyle choices can offset the genetic risk of developing Alzheimer’s and other forms of dementia. Read & Research Alzheimer’s More

How having a close relative with Alzheimer's may affect cognition">How having a close relative with Alzheimer's may affect cognition

New research suggests that having a relative with Alzheimer’s disease may put people at risk of a premature decline in memory and learning. Read & Research Alzheimer’s More

Alzheimer's: Cell mechanism removes defective protein">Alzheimer's: Cell mechanism removes defective protein

Buildup of defective tau protein is a hallmark of Alzheimer’s disease. Now, scientists have identified a molecule that helps clear it from brain cells. Read & Research Alzheimer’s More

Biopsychosocial frailty and the risk of incident dementia: The Italian longitudinal study on aging">Biopsychosocial frailty and the risk of incident dementia: The Italian longitudinal study on aging

Frailty is a critical intermediate status of the aging process including physical, cognitive, and psychosocial domains/phenotypes. We operationalized a new biopsychosocial frailty (BF) construct, estimating its impact on the risk of incident dementia and its subtypes. Read & Research Alzheimer’s More

Alzheimer's blood test almost 'usable in routine clinical care'">Alzheimer's blood test almost 'usable in routine clinical care'

A new blood test for detecting Alzheimer’s disease approaches ‘a level of accuracy that is usable in routine clinical care around the world.’ Read & Research Alzheimer’s More

Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration">Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration

Some models of therapy for neurodegenerative diseases envision starting treatment before symptoms develop. Demonstrating that such treatments are effective requires accurate knowledge of when symptoms would have started without treatment. Familial frontotemporal lobar degeneration offers a unique opportunity to develop predictors of symptom onset. Read & Research Alzheimer’s More

Can social interaction predict cognitive decline?">Can social interaction predict cognitive decline?

A number of studies have assessed the relationship between social interaction and dementia; the latest adds to the increasingly complex picture. Read & Research Alzheimer’s More

Bioinformatics strategy to advance the interpretation of Alzheimer's disease GWAS discoveries: The roads from association to causation">Bioinformatics strategy to advance the interpretation of Alzheimer's disease GWAS discoveries: The roads from association to causation

Genome-wide association studies (GWAS) discovered multiple late-onset Alzheimer’s disease (LOAD)-associated SNPs and inferred the genes based on proximity; however, the actual causal genes are yet to be identified. Read & Research Alzheimer’s More

These common drugs may increase dementia risk">These common drugs may increase dementia risk

Drugs that doctors often use in the treatment of overactive bladder, gastrointestinal conditions, and depression may increase dementia risk by almost half. Read & Research Alzheimer’s More

Hypertension treatment may slow down Alzheimer's progression">Hypertension treatment may slow down Alzheimer's progression

New research finds that nilvadipine, a drug doctors commonly use to treat high blood pressure, increases the blood flow to the brain’s hippocampus. Read & Research Alzheimer’s More

A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies">A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies

Recent studies in neurodegenerative conditions have increasingly highlighted that the same neuropathology can trigger different clinical phenotypes or, vice-versa, that similar phenotypes can be triggered by different neuropathologies. This evidence has called for the adoption of a pathology spectrum-based approach to study neurodegenerative proteinopathies. These conditions share brain deposition of Read & Research Alzheimer’s More

Atrial fibrillation may raise dementia risk by 50%">Atrial fibrillation may raise dementia risk by 50%

According to the largest research of its kind yet, atrial fibrillation may raise the risk of dementia even in people who did not experience a stroke. Read & Research Alzheimer’s More

Paradoxical lucidity: A potential paradigm shift for the neurobiology and treatment of severe dementias">Paradoxical lucidity: A potential paradigm shift for the neurobiology and treatment of severe dementias

Unexpected cognitive lucidity and communication in patients with severe dementias, especially around the time of death, have been observed and reported anecdotally. Here, we review what is known about this phenomenon, related phenomena that provide insight into potential mechanisms, ethical implications, and methodologic considerations for systematic investigation. We conclude that Read & Research Alzheimer’s More

Coronary heart disease may speed up cognitive decline">Coronary heart disease may speed up cognitive decline

A study of adults aged 50 and over found that decline in memory and thinking was faster after a heart attack or angina, but not before. Read & Research Alzheimer’s More

Coronary heart disease may speed up cognitive decline">Coronary heart disease may speed up cognitive decline

A study of adults aged 50 and over found that decline in memory and thinking was faster after a heart attack or angina, but not before. Read & Research Alzheimer’s More

How frontotemporal dementia affects 'moral emotions'">How frontotemporal dementia affects 'moral emotions'

Scientists find a key difference between Alzheimer’s and frontotemporal dementia: the latter affects a person’s ‘moral emotions’ while the former does not. Read & Research Alzheimer’s More

How is education linked to Alzheimer's progress?">How is education linked to Alzheimer's progress?

New research asks to what extent, if any, a person’s level of education is linked to the presence of Alzheimer’s disease and the rate of cognitive decline. Read & Research Alzheimer’s More

A deep learning model for early prediction of Alzheimer's disease dementia based on hippocampal magnetic resonance imaging data">A deep learning model for early prediction of Alzheimer's disease dementia based on hippocampal magnetic resonance imaging data

It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer’s disease (AD) dementia. Read & Research Alzheimer’s More

Contributions of vascular and Alzheimer's disease pathology to dementia">Contributions of vascular and Alzheimer's disease pathology to dementia

Although Alzheimer’s disease (AD) is frequently cited as the most common type of dementia, the relative contributions of vascular and neurodegenerative pathology to clinical dementia have been actually obscure. The systematic review of studies reporting clinicopathologic data of dementia cases sheds important light on this issue [1]. Ten reports were Read & Research Alzheimer’s More

How ultrasound could help curb Parkinson's">How ultrasound could help curb Parkinson's

Mouse study shows that focused ultrasound and injected microbubbles can help curb early Parkinson’s disease by allowing drugs to access the brain. Read & Research Alzheimer’s More

Parkinson's: New gene therapy shows promise for prevention">Parkinson's: New gene therapy shows promise for prevention

Researchers from Japan have tested a new gene therapy against Parkinson’s disease using mouse models. Their results suggest that the approach is effective. Read & Research Alzheimer’s More

Can blood pressure drugs help reduce dementia risk?">Can blood pressure drugs help reduce dementia risk?

A large study analyzing the medical data of thousands of people suggests that dementia incidence is lower among those who take blood pressure medication. Read & Research Alzheimer’s More

Association of TLR4 with Alzheimer's disease risk and presymptomatic biomarkers of inflammation">Association of TLR4 with Alzheimer's disease risk and presymptomatic biomarkers of inflammation

A coding variant in the TLR4 receptor (rs4986790), previously associated with longevity and Alzheimer’s disease (AD) risk reduction, was examined in a population isolate (Québec Founder Population [QFP]) and in presymptomatic individuals with a parental history of AD (Pre-Symptomatic Evaluation of Novel or Experimental Treatment for Alzheimer’s Disease [PREVENT-AD]). Read & Research Alzheimer’s More

Neuroimaging correlates with neuropathologic schemes in neurodegenerative disease">Neuroimaging correlates with neuropathologic schemes in neurodegenerative disease

Neuroimaging biomarkers are important for early diagnosis of Alzheimer’s disease, and comparing multimodality neuroimaging to autopsy data is essential. Read & Research Alzheimer’s More

Is virtual reality the next frontier of Alzheimer's diagnosis?">Is virtual reality the next frontier of Alzheimer's diagnosis?

New research suggests that using a virtual reality simulator could be more effective at detecting Alzheimer’s disease than standard tests. Read & Research Alzheimer’s More

Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype">Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype

We estimated the age-specific duration of the preclinical, prodromal, and dementia stages of Alzheimer’s disease (AD) and the influence of sex, setting, apolipoprotein E (APOE) genotype, and cerebrospinal fluid tau on disease duration. Read & Research Alzheimer’s More

Motoric cognitive risk syndrome and predictors of transition to dementia: A multicenter study">Motoric cognitive risk syndrome and predictors of transition to dementia: A multicenter study

To report clinical predictors of transition to dementia in motoric cognitive risk syndrome (MCR), a predementia syndrome characterized by cognitive complaints and slow gait. Read & Research Alzheimer’s More