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Helicobacter pylori and the risk of dementia: A population-based study">Helicobacter pylori and the risk of dementia: A population-based study

Helicobacter pylori infection might increase risk of dementia, but available evidence is inconsistent, and longitudinal studies are sparse. We investigated the association between H. pylori serology and dementia risk in a population-based cohort. Read & Research Alzheimer’s More

Smoking and diabetes 'risk factors' for calcium buildup in brain">Smoking and diabetes 'risk factors' for calcium buildup in brain

A study of brain CT scans of patients with memory problems found that diabetes and smoking were linked to hippocampal calcifications. Read & Research Alzheimer’s More

Even slightly elevated blood pressure increases dementia risk">Even slightly elevated blood pressure increases dementia risk

Hypertension in middle age is known to increase the risk of dementia, but so far the specifics are unclear. A new study sheds fresh light on this matter. Read & Research Alzheimer’s More

Understanding the impact of sex and gender in Alzheimer's disease: A call to action">Understanding the impact of sex and gender in Alzheimer's disease: A call to action

Precision medicine methodologies and approaches have advanced our understanding of the clinical presentation, development, progression, and management of Alzheimer’s disease (AD) dementia. However, sex and gender have not yet been adequately integrated into many of these approaches. Read & Research Alzheimer’s More

Alcohol may prime the brain for Alzheimer's, but how?">Alcohol may prime the brain for Alzheimer's, but how?

Heavy drinking is a risk factor for the development of Alzheimer’s. New research now reveals how alcohol may endanger the brain by impairing its defenses. Read & Research Alzheimer’s More

Research confirms that social interaction protects memory">Research confirms that social interaction protects memory

Memory naturally declines with age, but a new study shows that there may be an easy way to protect it — namely, by staying socially active. Read & Research Alzheimer’s More

Link between depression and cognitive decline explored">Link between depression and cognitive decline explored

Following an analysis of existing studies, researchers conclude that there is a link between depression and age-related cognitive decline. Read & Research Alzheimer’s More

New thinking about thinking, part two. Theoretical articles for Alzheimer's & Dementia">New thinking about thinking, part two. Theoretical articles for Alzheimer's & Dementia

There is one question often asked during scientific meetings, business travel, or dinner parties that is just as easily and equally posed by members of the research community, the general public, or by friends and family: what’s new in Alzheimer’s research? Today, there is growing interest from readers into the Read & Research Alzheimer’s More

'Early hearing loss could pave the way for dementia,' study says">'Early hearing loss could pave the way for dementia,' study says

Young people should take better care of their hearing, new research warns, or they may expose themselves to a heightened risk of cognitive impairments. Read & Research Alzheimer’s More

Estimation of lifetime risks of Alzheimer's disease dementia using biomarkers for preclinical disease">Estimation of lifetime risks of Alzheimer's disease dementia using biomarkers for preclinical disease

Lifetime risks are the probabilities of progressing to Alzheimer’s disease (AD) dementia during one’s lifespan. Here, we report the first estimates of the lifetime and ten-year risks of AD dementia based on age, gender, and biomarker tests for preclinical disease. Read & Research Alzheimer’s More

Peripheral complement interactions with amyloid β peptide in Alzheimer's disease: Polymorphisms, structure, and function of complement receptor 1">Peripheral complement interactions with amyloid β peptide in Alzheimer's disease: Polymorphisms, structure, and function of complement receptor 1

Genome-wide association studies consistently show that single nucleotide polymorphisms (SNPs) in the complement receptor 1 (CR1) gene modestly but significantly alter Alzheimer’s disease (AD) risk. Follow-up research has assumed that CR1 is expressed in the human brain despite a paucity of evidence for its function there. Alternatively, erythrocytes contain >80% Read & Research Alzheimer’s More

APOE-ε4 associates with hippocampal volume, learning, and memory across the spectrum of Alzheimer's disease and dementia with Lewy bodies">APOE-ε4 associates with hippocampal volume, learning, and memory across the spectrum of Alzheimer's disease and dementia with Lewy bodies

Although the apolipoprotein E ε4-allele (APOE-ε4) is a susceptibility factor for Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB), its relationship with imaging and cognitive measures across the AD/DLB spectrum remains unexplored. Read & Research Alzheimer’s More

$414 million Alzheimer's and dementia research funding increase signed into law">$414 million Alzheimer's and dementia research funding increase signed into law

In March, a $414 million increase for Alzheimer’s disease (AD) and dementia research funding at the National Institutes of Health and Kevin and Avonte’s Law, important legislation to protect those who wander, were signed into law. Read & Research Alzheimer’s More

Parkinson's, dementia: Is this the key to preventive therapy?">Parkinson's, dementia: Is this the key to preventive therapy?

A landmark study sheds light on the underlying mechanisms that impact neural health in Parkinson’s disease and dementia. Can it lead to better treatments? Read & Research Alzheimer’s More

Cholesterol found to play a role in Alzheimer's">Cholesterol found to play a role in Alzheimer's

According to the latest study, cholesterol plays a role in the formation of plaques in Alzheimer’s disease. The findings open new avenues for drug design. Read & Research Alzheimer’s More

The Brain Health Registry: An internet-based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies">The Brain Health Registry: An internet-based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies

Recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies and clinical trials limit the development of new treatments. Widespread Internet use allows data capture from participants in an unsupervised setting. The Brain Health Registry, a website and online registry, collects data from participants and their study partners. Read & Research Alzheimer’s More

New dementia risk factors uncovered">New dementia risk factors uncovered

Using machine learning techniques, researchers reveal new dementia risks. They conclude that marital status, BMI, and sleep may all play a role. Read & Research Alzheimer’s More

Alzheimer's: Are changes in the brain's attention hub at fault?">Alzheimer's: Are changes in the brain's attention hub at fault?

As we grow older, we find it harder to stay focused, perhaps due to changes in the brain’s attention hub. Could this also drive the onset of Alzheimer’s? Read & Research Alzheimer’s More

Japanese and North American Alzheimer's Disease Neuroimaging Initiative studies: Harmonization for international trials">Japanese and North American Alzheimer's Disease Neuroimaging Initiative studies: Harmonization for international trials

We conducted Japanese Alzheimer’s Disease Neuroimaging Initiative (J-ADNI) and compared the basic characteristics and progression profiles with those of ADNI in North America. Read & Research Alzheimer’s More

Even mild TBI might raise dementia risk">Even mild TBI might raise dementia risk

A study that followed more than 350,000 veterans found a raised risk of dementia in those who had had TBI — even mild TBI without loss of consciousness. Read & Research Alzheimer’s More

New molecule may stop Alzheimer's from spreading">New molecule may stop Alzheimer's from spreading

Researchers have found a small molecule that can block the spread of the toxic protein tau, a hallmark of Alzheimer’s progression. Read & Research Alzheimer’s More

Fractal regulation and incident Alzheimer's disease in elderly individuals">Fractal regulation and incident Alzheimer's disease in elderly individuals

Healthy physiological systems exhibit fractal regulation (FR), generating similar fluctuation patterns in physiological outputs across different time scales. FR in motor activity is degraded in dementia, and the degradation correlates to cognitive decline. We tested whether degraded FR predicts Alzheimer’s disease dementia. Read & Research Alzheimer’s More